Evidence map›Paper›PMID 26636282›Full record

ArticleJournal of musculoskeletal & neuronal interactions2015

Arm bone loading index predicts DXA musculoskeletal outcomes in two samples of post-menarcheal girls.

J N Dowthwaite, K A Dunsmore, N M Gero, A O Burzynski, C A Sames, P F Rosenbaum, T A Scerpella

Abstract read
In one paragraph

Article in Journal of musculoskeletal & neuronal interactions, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Peak bone mass development in U.S. females with varied physical activity patterns: a longitudinal view using three maturational clocks.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  2. Article
  3. Biological Benchmarks for Adult Bone Mass Proportions in Young Females: A Prospective Longitudinal Analysis.American journal of human biology : the official journal of the Human Biology Council · 2025
    Article
  4. Article
  5. A 2-yr, School-Based Resistance Exercise Pilot Program Increases Bone Accrual in Adolescent Girls.Translational journal of the American College of Sports Medicine · 2019
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

J N DowthwaiteDepartment of Orthopedic Surgery, SUNY Upstate Medical University, Syracuse, NY.
K A Dunsmore
N M Gero
A O Burzynski
C A Sames
P F Rosenbaum
T A Scerpella

Funding

Sustained Skeletal Benefits of Adolescent ExerciseR01AR054145 · NIAMS · UPSTATE MEDICAL UNIVERSITY · PI SCERPELLA, TAMARA A · 2008 to 2012
$1.7M
Role of impact activity in peripubertal bone accrualR03AR047613 · NIAMS · UPSTATE MEDICAL UNIVERSITY · PI SCERPELLA, TAMARA A · 2001 to 2003
$228k
NIAMS NIH HHS R01 AR054145NIAMS NIH HHS R01 AR54145NIAMS NIH HHS R03 AR047613
6 · The paper itself

Abstract

objectiveA site-specific bone loading index was developed to predict post-menarcheal arm bone mass, geometry, areal density and non-bone lean mass using organized activity records.

methodsTwo cohorts of post-menarcheal girls (A= 55, B= 48) met analysis inclusion criteria: (1) Whole body and non-dominant radius DXA scans +1.0 to +2.6 years post-menarche; (2) detailed, organized activity records available for 36 months prior to the focal DXA scan; (3) accompanying anthropometric data. DXA non-dominant arm and radius regions of interest (1/3, Ultradistal (UD)) were evaluated. An arm bone loading index (arm totBLI) was developed and refined to describe >50 activities. Separate regression analyses for Cohorts A&B tested explanatory value of arm totBLI for DXA outcomes, accounting for gynecological age, height and whole body non-bone lean mass.

resultsIn both cohorts, arm totBLI reflecting 3 years of peri-menarcheal activity exposure exhibited strong explanatory value for post-menarcheal radius and arm outcomes (squared semi-partial r =0.07-0.34, p<0.05), except Arm Area. For both cohorts and most outcomes, arm totBLI explained significant variance, even after adjusting for local muscle mass.

conclusionsIn two independent cohorts, arm totBLI may consistently indicate osteogenic and sarcogenic properties of represented activities; additional research is necessary for further refinement and validation.

Indexed as

Absorptiometry, PhotonAdolescentAnthropometryArm BonesBody CompositionBone DevelopmentChildFemaleHumansMenarcheMotor ActivityMuscle, Skeletal

Identifiers

PMID26636282
PMCPMC5628596

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.