Evidence map›Paper›PMID 26635717›Full record

ArticleFrontiers in neurology2015

Feasibility and Diagnostic Accuracy of Ischemic Stroke Territory Recognition Based on Two-Dimensional Projections of Three-Dimensional Diffusion MRI Data.

Jana Katharina Wrosch, Bastian Volbers, Philipp Gölitz, Daniel Frederic Gilbert, Stefan Schwab, Arnd Dörfler, Johannes Kornhuber, Teja Wolfgang Groemer

Erratum issuedAbstract read
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Article in Frontiers in neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Jana Katharina WroschDepartment of Psychiatry and Psychotherapy, Friedrich-Alexander University of Erlangen-Nuremberg , Erlangen , Germany.
Bastian VolbersDepartment of Psychiatry and Psychotherapy, Friedrich-Alexander University of Erlangen-Nuremberg , Erlangen , Germany ; Department of Neurology, Friedrich-Alexander University of Erlangen-Nuremberg , Erlangen , Germany.
Philipp GölitzDepartment of Neuroradiology, Friedrich-Alexander University of Erlangen-Nuremberg , Erlangen , Germany.
Daniel Frederic GilbertInstitute of Medical Biotechnology, Friedrich-Alexander University of Erlangen-Nuremberg , Erlangen , Germany.
Stefan SchwabDepartment of Neurology, Friedrich-Alexander University of Erlangen-Nuremberg , Erlangen , Germany.
Arnd DörflerDepartment of Neuroradiology, Friedrich-Alexander University of Erlangen-Nuremberg , Erlangen , Germany.
Johannes KornhuberDepartment of Psychiatry and Psychotherapy, Friedrich-Alexander University of Erlangen-Nuremberg , Erlangen , Germany.
Teja Wolfgang GroemerDepartment of Psychiatry and Psychotherapy, Friedrich-Alexander University of Erlangen-Nuremberg , Erlangen , Germany ; Psychiatric and Neurological Ambulatory Care Office , Bamberg , Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was conducted to assess the feasibility and diagnostic accuracy of brain artery territory recognition based on geoprojected two-dimensional maps of diffusion MRI data in stroke patients. In this retrospective study, multiplanar diffusion MRI data of ischemic stroke patients was used to create a two-dimensional map of the entire brain. To guarantee correct representation of the stroke, a computer-aided brain artery territory diagnosis was developed and tested for its diagnostic accuracy. The test recognized the stroke-affected brain artery territory based on the position of the stroke in the map. The performance of the test was evaluated by comparing it to the reference standard of each patient's diagnosed stroke territory on record. This study was designed and conducted according to Standards for Reporting of Diagnostic Accuracy (STARD). The statistical analysis included diagnostic accuracy parameters, cross-validation, and Youden Index optimization. After cross-validation on a cohort of 91 patients, the sensitivity of this territory diagnosis was 81% with a specificity of 87%. With this, the projection of strokes onto a two-dimensional map is accurate for representing the affected stroke territory and can be used to provide a static and printable overview of the diffusion MRI data. The projected map is compatible with other two-dimensional data such as EEG and will serve as a useful visualization tool.

Indexed as

computer-aided detection and diagnosisdiffusion-weighted imagingdimensionality reductionmagnetic resonance imagingstroke territoriesvalidationvisualization

Identifiers

PMID26635717
PMCPMC4652171

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