ArticleJournal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology2015
Assessing the first wave of epidemiological studies of nanomaterial workers.
Article in Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Current state of knowledge on the health effects of engineered nanomaterials in workers: a systematic review of human studies and epidemiological investigations.Scandinavian journal of work, environment & health · 2019Pooled it
- Systematic Review of Screening and Surveillance Programs to Protect Workers from Nanomaterials.PloS one · 2016Pooled it
- Transcriptomics insight into occupational exposure to engineered nanoparticles.Nanomedicine (London, England) · 2025Article
- Preventive effect of precautionary lowered exposure or adaptation of nanomaterial workers?Central European journal of public health · 2025Article
- Quantile regression for longitudinal data with values below the limit of detection and time-dependent covariates-application to modeling carbon nanotube and nanofiber exposures.Annals of work exposures and health · 2024Article
- Evaluation of biological markers for the risk assessment of carbon black in epidemiological studies.Frontiers in public health · 2024Review
- Ag- but Not ZnO-Nanoparticles Disturb the Airway Epithelial Barrier at Subtoxic Concentrations.Pharmaceutics · 2023Article
- U. S. federal perspective on critical research issues in nanoEHS.Environmental science. Nano · 2023Article
- Three-Year Study of Markers of Oxidative Stress in Exhaled Breath Condensate in Workers Producing Nanocomposites, Extended by Plasma and Urine Analysis in Last Two Years.Nanomaterials (Basel, Switzerland) · 2020Article
- Hydroxyl functionalized multi-walled carbon nanotubes modulate immune responses without increasing 2009 pandemic influenza A/H1N1 virus titers in infected mice.Toxicology and applied pharmacology · 2020Article
- Resolution of Pulmonary Inflammation Induced by Carbon Nanotubes and Fullerenes in Mice: Role of Macrophage Polarization.Frontiers in immunology · 2020Article
- Integration of inflammation, fibrosis, and cancer induced by carbon nanotubes.Nanotoxicology · 2019Review
- Nanotechnology in Transportation Vehicles: An Overview of Its Applications, Environmental, Health and Safety Concerns.Materials (Basel, Switzerland) · 2019Review
- NanoTiONanomaterials (Basel, Switzerland) · 2019Article
- Predicting Occupational Exposures to Carbon Nanotubes and Nanofibers Based on Workplace Determinants Modeling.Annals of work exposures and health · 2019Article
- Article
- The asbestos-carbon nanotube analogy: An update.Toxicology and applied pharmacology · 2018Review
- Biological monitoring of workers exposed to engineered nanomaterials.Toxicology letters · 2018Review
- Deep Airway Inflammation and Respiratory Disorders in Nanocomposite Workers.Nanomaterials (Basel, Switzerland) · 2018Article
- Markers of Oxidative Stress in the Exhaled Breath Condensate of Workers Handling Nanocomposites.Nanomaterials (Basel, Switzerland) · 2018Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The results of early animal studies of engineered nanomaterials (ENMs) and air pollution epidemiology suggest that it is important to assess the health of ENM workers. Initial epidemiological studies of workers' exposure to ENMs (<100 nm) are reviewed and characterized for their study designs, findings, and limitations. Of the 15 studies, 11 were cross-sectional, 4 were longitudinal (1 was both cross-sectional and longitudinal in design), and 1 was a descriptive pilot study. Generally, the studies used biologic markers as the dependent variables. All 11 cross-sectional studies showed a positive relationship between various biomarkers and ENM exposures. Three of the four longitudinal studies showed a negative relationship; the fourth showed positive findings after a 1-year follow-up. Each study considered exposure to ENMs as the independent variable. Exposure was assessed by mass concentration in 10 studies and by particle count in six studies. Six of them assessed both mass and particle concentrations. Some of the studies had limited exposure data because of inadequate exposure assessment. Generally, exposure levels were not very high in comparison to those in human inhalation chamber studies, but there were some exceptions. Most studies involved a small sample size, from 2 to 258 exposed workers. These studies represent the first wave of epidemiological studies of ENM workers. They are limited by small numbers of participants, inconsistent (and in some cases inadequate) exposure assessments, generally low exposures, and short intervals between exposure and effect. Still, these studies are a foundation for future work; they provide insight into where ENM workers are experiencing potentially adverse effects that might be related to ENM exposures.
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