Evidence map›Paper›PMID 26635132›Full record

ArticleArthritis research & therapy2015

Determinants of patient preferences for total knee replacement: African-Americans and whites.

C Kent Kwoh, Ernest R Vina, Yona K Cloonan, Michael J Hannon, Robert M Boudreau, Said A Ibrahim

Open access · goldAbstract read
In one paragraph

Article in Arthritis research & therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 3 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 76 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Variability in Affect and Willingness to Take Medication.Medical decision making : an international journal of the Society for Medical Decision Making · 2018
    Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Awareness about total knee replacement among Saudi population.Journal of family medicine and primary care · 2022
    Article
  16. Review
  17. Article
  18. Racial Disparities in Total Joint Arthroplasty.Current reviews in musculoskeletal medicine · 2021
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

C Kent KwohUniversity of Arizona School of Medicine and University of Arizona Arthritis Center, 1501 N. Campbell Ave., PO Box 245093, Tucson, Arizona, 85724, USA. CKwoh@arthritis.arizona.edu.
Ernest R VinaUniversity of Arizona School of Medicine and University of Arizona Arthritis Center, 1501 N. Campbell Ave., PO Box 245093, Tucson, Arizona, 85724, USA. evina@email.arizona.edu.
Yona K CloonanUniversity of Pittsburgh School of Public Health, 130 De Soto St., 127 Parran Hall, Pittsburgh, Pennsylvania, 15261, USA. cloonany@edc.pitt.edu.
Michael J HannonUniversity of Pittsburgh School of Medicine, 130 North Bellefield Ave., 4th Floor, Pittsburgh, Pennsylvania, 15213, USA. michaeljhannon@gmail.com.
Robert M BoudreauUniversity of Pittsburgh School of Public Health, 130 De Soto St., 127 Parran Hall, Pittsburgh, Pennsylvania, 15261, USA. BoudreauR@edc.pitt.edu.
Said A IbrahimUniversity of Pennsylvania Perelman School of Medicine and Philadelphia VA Medical Center, 3900 Woodland Ave., Philadelphia, Pennsylvania, 19104, USA. Said.Ibrahim2@va.gov.
University of Arizona · US

Funding

PITT-MCRC for Rheumatic and Musculoskeletal DiseasesP60AR054731 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KWOH, C KENT · 2007 to 2011
$4.9M
Racial Disparity in the Utilization of Joint Replacement for OsteoarthritisK24AR055259 · NIAMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI IBRAHIM, SAID A · 2007 to 2019
$1.2M
NIAMS NIH HHS K24 AR055259NIAMS NIH HHS P60 AR054731NIAMS NIH HHS P60-AR-054731
6 · The paper itself

Abstract

introductionPatient preferences contribute to marked racial disparities in the utilization of total knee replacement (TKR). The objectives of this study were to identify the determinants of knee osteoarthritis (OA) patients' preferences regarding TKR by race and to identify the variables that may mediate racial differences in willingness to undergo TKR.

methodsFive hundred fourteen White (WH) and 285 African-American (AA) patients with chronic knee pain and radiographic evidence of OA participated in the study. Participants were recruited from the community, an academic medical center, and a Veterans Affairs hospital. Structured interviews were conducted to collect socio-demographics, disease severity, socio-cultural determinants, and treatment preferences. Logistic regression was performed, stratified by race, to identify determinants of preferences. Clinical and socio-cultural factors were entered simultaneously into the models. Stepwise selection identified factors for inclusion in the final models (p < 0.20).

resultsCompared to WHs, AAs were less willing to undergo TKR (80 % vs. 62 %, respectively). Better expectations regarding TKR surgery outcomes determined willingness to undergo surgery in both AAs (odds ratio (OR) 2.08, 95 % confidence interval (CI) 0.91-4.79 for 4(th) vs. 1(st) quartile) and WHs (OR 5.11, 95 % CI 2.31-11.30 for 4(th) vs. 1(st) quartile). Among AAs, better understanding of the procedure (OR 1.80, 95 % CI 0.97-3.35), perceiving a short hospital course (OR 0.81, 95 % CI 0.58-1.13), and believing in less post-surgical pain (OR 0.73, 95 % CI 0.39-1.35) and walking difficulties (OR 0.66, 95 % CI 0.37-1.16) also determined willingness. Among WHs, having surgical discussion with a physician (OR 1.96, 95 % CI 1.05-3.68), not ever receiving surgical referral (OR 0.56, 95 % CI 0.32-0.99), and higher trust in the healthcare system (OR 1.58, 95 % CI 0.75-3.31 for 4(th) vs. 1(st) quartile) additionally determined willingness. Among the variables considered, only knowledge-related matters pertaining to TKR attenuated the racial difference in knee OA patients' treatment preference.

conclusionsExpectations of surgical outcomes influence preference for TKR in all patients, but clinical and socio-cultural factors exist that shape marked racial differences in preferences for TKR. Interventions to reduce or eliminate racial disparities in the utilization of TKR should consider and target these factors.

Indexed as

AgedArthroplasty, Replacement, KneeBlack or African AmericanFemaleHumansMaleMiddle AgedOsteoarthritis, KneePatient PreferenceWhite People

Identifiers

PMID26635132
PMCPMC4669671
OpenAlexW2186277515

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.