ArticleMolecular neurobiology2016
Topological Reorganization of the Default Mode Network in Irritable Bowel Syndrome.
Article in Molecular neurobiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
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Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A systematic review of associations between functional connectivity, mood and cognition in patients with irritable bowel syndrome.Brain imaging and behavior · 2026Pooled it
- Resting-state functional MRI activity and connectivity in inflammatory bowel disease: a systematic review.Neuroradiology · 2025Pooled it
- Functional changes of default mode network and structural alterations of gray matter in patients with irritable bowel syndrome: a meta-analysis of whole-brain studies.Frontiers in neuroscience · 2023Pooled it
- Causal relationships between irritable bowel syndrome and brain functional networks: A Mendelian randomization study.Journal of translational internal medicine · 2026Article
- Aberrant functional connectivity patterns in the pregenual anterior cingulate cortex and anterior midcingulate cortex of patients with irritable bowel syndrome accompanied by depressive symptoms.Brain imaging and behavior · 2025Article
- Brain identification of IBS patients based on GBDT and multiple imaging techniques.Physical and engineering sciences in medicine · 2024Article
- Study of dynamic brain function in irritable bowel syndrome via Hidden Markov Modeling.Frontiers in neuroscience · 2024Article
- The neurobiology of irritable bowel syndrome.Molecular psychiatry · 2023Review
- Functional Neuroimaging in Irritable Bowel Syndrome: A Systematic Review Highlights Common Brain Alterations With Functional Movement Disorders.Journal of neurogastroenterology and motility · 2022Review
- Abnormal Dynamics of Functional Connectivity Density Associated With Chronic Neck Pain.Frontiers in molecular neuroscience · 2022Article
- Aberrant resting-state functional connectivity and topological properties of the subcortical network in functional dyspepsia patients.Frontiers in molecular neuroscience · 2022Article
- Disrupted Cerebellar-Default Mode Network Functional Connectivity in Major Depressive Disorder With Gastrointestinal Symptoms.Frontiers in cellular neuroscience · 2022Article
- Altered Intra- and Inter-Network Functional Connectivity in Patients With Crohn's Disease: An Independent Component Analysis-Based Resting-State Functional Magnetic Resonance Imaging Study.Frontiers in neuroscience · 2022Article
- Abnormal Default Mode Network Homogeneity in Major Depressive Disorder With Gastrointestinal Symptoms at Rest.Frontiers in aging neuroscience · 2022Article
- The Role of Medial Prefrontal Cortex in Acupuncture Treatment for Functional Dyspepsia.Frontiers in neuroscience · 2022Article
- Altered Resting Brain Functions in Patients With Irritable Bowel Syndrome: A Systematic Review.Frontiers in human neuroscience · 2022Review
- Temporal Grading Index of Functional Network Topology Predicts Pain Perception of Patients With Chronic Back Pain.Frontiers in neurology · 2022Article
- Inter-hemispheric Functional Connections Are More Vulnerable to Attack Than Structural Connection in Patients With Irritable Bowel Syndrome.Journal of neurogastroenterology and motility · 2021Article
- A Resting-state Functional Magnetic Resonance Imaging Study of Whole-brain Functional Connectivity of Voxel Levels in Patients With Irritable Bowel Syndrome With Depressive Symptoms.Journal of neurogastroenterology and motility · 2021Article
- Altered brain structural connectivity in patients with longstanding gut inflammation is correlated with psychological symptoms and disease duration.NeuroImage. Clinical · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to investigate the topological reorganization of the brain default mode network (DMN) in patients with irritable bowel syndrome (IBS) using resting-state functional magnetic resonance imaging (rs-fMRI). With approval by our ethics committee, rs-fMRI was prospectively performed in 31 IBS patients (25 male, 27 ± 8 years) and 32 healthy controls (25 male, 29 ± 9 years). The DMN was determined by unbiased seed-based functional connectivity (FC) analysis and then parcellated into several subregions. FC across all pairs of DMN subregions was computed to construct the DMN architecture, for which topological properties were characterized by graph theoretical approaches. Pearson correlation was performed between abnormal DMN inter-regional FC and network measures and clinical indices in IBS patients. Compared to healthy controls, IBS patients showed decreased DMN inter-regional FC between the anterior cingulate cortex and precuneus, the medial orbital of the superior frontal gyrus (ORBsupmed) and precuneus, and the middle temporal gyrus and precuneus. IBS patients also showed decreased DMN global efficiency (E
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Registered trials
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