Evidence map›Paper›PMID 26635031›Full record

ArticleTobacco control2016

Thirdhand smoke contamination in hospital settings: assessing exposure risk for vulnerable paediatric patients.

Thomas F Northrup, Amir M Khan, Peyton Jacob, Neal L Benowitz, Eunha Hoh, Melbourne F Hovell, Georg E Matt, Angela L Stotts

Open access · greenAbstract read
In one paragraph

Article in Tobacco control, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

  1. Analysis of Assessment Methods for Detecting Nicotine Residue and Its Impact on Humans: A Systematic Review.International journal of environmental research and public health · 2025
    Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Development of a Smoke-Free Home Intervention for Families of Babies Admitted to Neonatal Intensive Care.International journal of environmental research and public health · 2022
    Article
  9. Review
  10. Article
  11. Observational
  12. Article
  13. Remediating Thirdhand Smoke Pollution in Multiunit Housing: Temporary Reductions and the Challenges of Persistent Reservoirs.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2021
    Article
  14. Thirdhand Smoke Contamination and Infant Nicotine Exposure in a Neonatal Intensive Care Unit: An Observational Study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2021
    Observational
  15. Article
  16. Thirdhand smoke: Genotoxicity and carcinogenic potential.Chronic diseases and translational medicine · 2020
    Article
  17. Article
  18. Article
  19. Effects of hydroxyapatite@poly-lactide-Toxicology research · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Thomas F NorthrupDepartment of Family and Community Medicine, The University of Texas Health Science Center at Houston (UTHealth) Medical School, Houston, Texas, USA.ORCID 0000-0002-3275-3168
Amir M KhanDepartment of Pediatrics, UTHealth Medical School; Medical Director Level III NICU, Children's Memorial Hermann Hospital, Houston, Texas, USA.
Peyton JacobDepartments of Medicine and Psychiatry, University of California San Francisco; Division of Clinical Pharmacology, San Francisco General Hospital Medical Center, San Francisco, California, USA.
Neal L BenowitzDepartments of Medicine and Bioengineering & Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA.
Eunha HohDivision of Environmental Health, Graduate School of Public Health, San Diego State University, San Diego, California, USA.
Melbourne F HovellCenter for Behavioral Epidemiology and Community Health, Graduate School of Public Health, San Diego State University, San Diego, California, USA.
Georg E MattDepartment of Psychology, San Diego State University, San Diego, California, USA.
Angela L StottsDepartment of Family and Community Medicine, Department of Psychiatry and Behavioral Sciences, UTHealth Medical School, Houston, Texas, USA.
San Diego State University · USMemorial Hermann · USSan Francisco General Hospital · USThe University of Texas Health Science Center · USThe University of Texas Health Science Center at Houston · USUniversity of California, San Francisco · US

Funding

Research Support CoreP30DA012393 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ST.HELEN, GIDEON · 1999 to 2024
$17.1M
Innovation for Smoke-Free Homes: Real-Time FeedbackR01HL103684 · NHLBI · SAN DIEGO STATE UNIVERSITY · PI HOVELL, MELBOURNE F · 2011 to 2015
$5.4M
Motivational Incentives to Reduce Secondhand Smoke in NICU Infants' HomesR01HL107404 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI STOTTS, ANGELA L · 2012 to 2016
$3.3M
NHLBI NIH HHS R01 HL103684NHLBI NIH HHS R01 HL107404NIDA NIH HHS P30 DA012393
6 · The paper itself

Abstract

backgroundTobacco has regained the status of the world's number two killer behind heart/vascular disease. Thirdhand smoke (THS) residue and particles from secondhand smoke (SHS) are suspected health hazards (eg, DNA damage) that are likely to contribute to morbidity and mortality, especially in vulnerable children. THS is easily transported and deposited indoors, where it persists and exposes individuals for months, creating potential health consequences in seemingly nicotine-free environments, particularly for vulnerable patients. We collected THS data to estimate infant exposure

methodsParticipants were mothers who smoked and had an infant in the NICU (N=5). Participants provided surface nicotine samples from their fingers, infants' crib/incubator and hospital-provided furniture. Infant urine was analysed for cotinine, cotinine's major metabolite:

resultsIncubators/cribs and other furniture had detectable surface nicotine. Detectable levels of cotinine, 3HC and NNAL were found in the infants' urine. DISCUSSION: THS appears to be ubiquitous, even in closely guarded healthcare settings. Future research will address potential health consequences and THS-reduction policies. Ultimately, hospital policies and interventions to reduce THS transport and exposure may prove necessary, especially for immunocompromised children.

Indexed as

Intensive Care Units, NeonatalCarcinogensCotinineEnvironmental ExposureEnvironmental MonitoringFemaleHumansInfant, NewbornNicotineNitrosaminesPregnancyTobacco Smoke Pollution4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanoneCarcinogensCotininehydroxycotinineNicotineNitrosaminesTobacco Smoke PollutionCarcinogensCotinineEnvironmentNicotinePriority/special populations

Identifiers

PMID26635031
PMCPMC4893002
OpenAlexW2266423485

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.