Evidence map›Paper›PMID 26635011›Full record

Trial reportTrials2015

Evaluation of the effectiveness of photodynamic therapy for the endodontic treatment of primary teeth: study protocol for a randomized controlled clinical trial.

Ana Carolina Costa da Mota, Marcela Leticia Leal Gonçalves, Carolina Bortoletto, Silvia Regina Olivan, Monica Salgueiro, Camila Godoy, Olga Maria Altavista, Marcelo Mendes Pinto, Anna Carolina Horliana, Lara J Motta and 1 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02485210 (Evaluation of the Effectiveness of Photodynamic Therapy as a Supporting for Endodontic Treatment of Deciduous Teeth), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02485210 phase1unknown statusnot on this mapstarted 2017, after this paper: background citation

Evaluation of the Effectiveness of Photodynamic Therapy as a Supporting for Endodontic Treatment of Deciduous Teeth

TypeinterventionalSponsorUniversity of Nove de JulhoRan2017 to 2018Enrolled30ConditionsTooth, NonvitalArmsEndodontic treatment
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. [Progress on photodynamic therapy in oral diseases].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2021
    Review
  6. Activation of Alkaline Irrigation Fluids in Endodontics.Materials (Basel, Switzerland) · 2017
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ana Carolina Costa da MotaBiofotonics Applied to Science Health Post Graduation Program Nove de Julho University, Rua Vergueiro, 249 - Liberdade CEP 0154001, São Paulo, SP, Brasil. ana_cmota@yahoo.com.br.
Marcela Leticia Leal GonçalvesBiofotonics Applied to Science Health Post Graduation Program Nove de Julho University, Rua Vergueiro, 249 - Liberdade CEP 0154001, São Paulo, SP, Brasil. marcelalleal@hotmail.com.
Carolina BortolettoBiofotonics Applied to Science Health Post Graduation Program Nove de Julho University, Rua Vergueiro, 249 - Liberdade CEP 0154001, São Paulo, SP, Brasil. carolbortoletto@ig.com.br.
Silvia Regina OlivanBiofotonics Applied to Science Health Post Graduation Program Nove de Julho University, Rua Vergueiro, 249 - Liberdade CEP 0154001, São Paulo, SP, Brasil. silviaolivan@uninove.br.
Monica SalgueiroBiofotonics Applied to Science Health Post Graduation Program Nove de Julho University, Rua Vergueiro, 249 - Liberdade CEP 0154001, São Paulo, SP, Brasil. monicasalgueiro@globo.com.
Camila GodoyBiofotonics Applied to Science Health Post Graduation Program Nove de Julho University, Rua Vergueiro, 249 - Liberdade CEP 0154001, São Paulo, SP, Brasil. cami_godoy@hotmail.com.
Olga Maria AltavistaBiofotonics Applied to Science Health Post Graduation Program Nove de Julho University, Rua Vergueiro, 249 - Liberdade CEP 0154001, São Paulo, SP, Brasil. altavista.ii@gmail.com.
Marcelo Mendes PintoBiofotonics Applied to Science Health Post Graduation Program Nove de Julho University, Rua Vergueiro, 249 - Liberdade CEP 0154001, São Paulo, SP, Brasil. mmpdent@hotmail.com.
Anna Carolina HorlianaBiofotonics Applied to Science Health Post Graduation Program Nove de Julho University, Rua Vergueiro, 249 - Liberdade CEP 0154001, São Paulo, SP, Brasil. annacrth@gmail.com.
Lara J MottaBiofotonics Applied to Science Health Post Graduation Program Nove de Julho University, Rua Vergueiro, 249 - Liberdade CEP 0154001, São Paulo, SP, Brasil. larajmotta@terra.com.br.
Sandra Kalil BussadoriBiofotonics Applied to Science Health Post Graduation Program Nove de Julho University, Rua Vergueiro, 249 - Liberdade CEP 0154001, São Paulo, SP, Brasil. Sandra.skb@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe elimination of pathogenic microorganisms from the root canal system is one of the major steps required for successful endodontic treatment. The aim of the proposed study is to conduct a randomized, controlled, clinical trial for the clinical and radiographic evaluation of the effectiveness of photodynamic therapy during the endodontic treatment of primary teeth.

methodsThirty primary anterior teeth in children aged 3 to 6 years old will be randomly divided into 2 groups: a control group, which will receive conventional treatment, and an experimental group, which will be subjected to photodynamic therapy. Microbiological evaluations will be performed before and after endodontic treatment. Moreover, clinical and radiographic evaluations will be performed on the day of treatment as well as 1, 3 and 6 months after treatment. Comparisons will be made of the two study groups. The data will be tabulated and presented in a descriptive, analytical fashion. Depending on the distribution (normal or non-normal), either the t test, ANOVA or the Mann-Whitney test will be used for analysis of the variables. The Wilcoxon test will be used for comparisons before and after treatment. P values<0.05 (95% significance level) will be considered indicative of statistically significant differences. DISCUSSION: As successful endodontic treatment is directly related to intra-canal bacterial disinfection and considering the difficult task of endodontic treatment in primary teeth, often due to difficulties in controlling young children, the internal anatomy of root canals and root resorption, the alternative of using PDT is a painless,easy-to-administer method that does not lead to microbial resistance and can assist in the achievement of successful endodontic treatment in primary teeth by eliminating the pain children can experience due to retreatment as well as premature tooth loss.

trial registrationThe protocol for this study was registered with Clinical Trials number NCT02485210 on 30 july 2015.

Indexed as

PhotochemotherapyAnalysis of VarianceBrazilChildChild, PreschoolClinical ProtocolsDental Care for ChildrenDental Pulp CavityFemaleHumansMaleMethylene BluePeriapical PeriodontitisPhotosensitizing AgentsRadiographyResearch DesignMethylene BluePhotosensitizing Agents

Identifiers

PMID26635011
PMCPMC4669610

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.