Evidence map›Paper›PMID 26634222›Full record

ArticleNeurobiology of stress

Mice lacking integrin β3 expression exhibit altered response to chronic stress.

Seth Varney, Keith F Polston, Tammy Jessen, Ana M D Carneiro

Open access · goldAbstract read
In one paragraph

Article in Neurobiology of stress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Integrins in synapse regulation.Nature reviews. Neuroscience · 2016
    Review
  5. A review of the peripheral levels of regulation by thyroid hormone.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Seth VarneyDepartment of Pharmacology, Vanderbilt University Medical Center, Nashville, TN 37232-6600, USA.
Keith F PolstonDepartment of Pharmacology, Vanderbilt University Medical Center, Nashville, TN 37232-6600, USA.
Tammy JessenDepartment of Pharmacology, Vanderbilt University Medical Center, Nashville, TN 37232-6600, USA.
Ana M D CarneiroDepartment of Pharmacology, Vanderbilt University Medical Center, Nashville, TN 37232-6600, USA.
Vanderbilt University Medical Center · US

Funding

Regulation of the Serotonin Transporter Function by Integrins in the Mouse BrainR01MH090256 · NIMH · VANDERBILT UNIVERSITY · PI CARNEIRO, ANA MARIN DIAS · 2011 to 2015
$1.9M
NIMH NIH HHS R01 MH090256
6 · The paper itself

Abstract

Recent studies indicate multiple roles for integrin αvβ3 in adult neurons, including response to pharmacological agents such as cocaine and selective serotonin reuptake inhibitors. In this study, we examined the role of the integrin β3 gene (

Indexed as

Chronic stressDepressionGlutamateIntegrinITGB3Serotonin

Identifiers

PMID26634222
PMCPMC4664197
OpenAlexW2188186842

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.