Evidence map›Paper›PMID 26634159›Full record

ArticleCase reports in dermatological medicine2015

Effectiveness of an Innovative Pulsed Electromagnetic Fields Stimulation in Healing of Untreatable Skin Ulcers in the Frail Elderly: Two Case Reports.

Fabio Guerriero, Emanuele Botarelli, Gianni Mele, Lorenzo Polo, Daniele Zoncu, Paolo Renati, Carmelo Sgarlata, Marco Rollone, Giovannoi Ricevuti, Niccolò Maurizi and 5 more

Open access · goldAbstract read
In one paragraph

Article in Case reports in dermatological medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Review
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  4. The Role of Physical Therapies in Wound Healing and Assisted Scarring.International journal of molecular sciences · 2023
    Review
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Fabio GuerrieroDepartment of Internal Medicine and Medical Therapy, Section of Geriatrics, University of Pavia, 27100 Pavia, Italy ; Agency for Elderly People Services, Hospital Santa Margherita, 27100 Pavia, Italy ; Ambra Elektron, Associazione Italiana di Biofisica per lo Studio dei Campi Elettromagnetici in Medicina, 00186 Rome, Italy.
Emanuele BotarelliAmbra Elektron, Associazione Italiana di Biofisica per lo Studio dei Campi Elettromagnetici in Medicina, 00186 Rome, Italy.
Gianni MeleAmbra Elektron, Associazione Italiana di Biofisica per lo Studio dei Campi Elettromagnetici in Medicina, 00186 Rome, Italy.
Lorenzo PoloAmbra Elektron, Associazione Italiana di Biofisica per lo Studio dei Campi Elettromagnetici in Medicina, 00186 Rome, Italy.
Daniele ZoncuAmbra Elektron, Associazione Italiana di Biofisica per lo Studio dei Campi Elettromagnetici in Medicina, 00186 Rome, Italy.
Paolo RenatiAmbra Elektron, Associazione Italiana di Biofisica per lo Studio dei Campi Elettromagnetici in Medicina, 00186 Rome, Italy ; Alberto Sorti Research Institute, Medicine and Metamolecular Biology, 10122 Turin, Italy.
Carmelo SgarlataDepartment of Internal Medicine and Medical Therapy, Section of Geriatrics, University of Pavia, 27100 Pavia, Italy.
Marco RolloneAgency for Elderly People Services, Hospital Santa Margherita, 27100 Pavia, Italy.
Giovannoi RicevutiDepartment of Internal Medicine and Medical Therapy, Section of Geriatrics, University of Pavia, 27100 Pavia, Italy ; Agency for Elderly People Services, Hospital Santa Margherita, 27100 Pavia, Italy.
Niccolò MauriziDepartment of Internal Medicine and Medical Therapy, Section of Geriatrics, University of Pavia, 27100 Pavia, Italy.
Matthew FrancisDepartment of Internal Medicine and Medical Therapy, Section of Geriatrics, University of Pavia, 27100 Pavia, Italy.
Mariangela RondanelliDepartment of Public Health, Experimental and Forensic Medicine, Section of Human Nutrition, Endocrinology and Nutrition Unit, University of Pavia, 27100 Pavia, Italy.
Simone PernaDepartment of Public Health, Experimental and Forensic Medicine, Section of Human Nutrition, Endocrinology and Nutrition Unit, University of Pavia, 27100 Pavia, Italy.
Davide GuidoAgency for Elderly People Services, Hospital Santa Margherita, 27100 Pavia, Italy ; Department of Public Health, Experimental and Forensic Medicine, Biostatistics and Clinical Epidemiology Unit, University of Pavia, 27100 Pavia, Italy.
Piero MannuAmbra Elektron, Associazione Italiana di Biofisica per lo Studio dei Campi Elettromagnetici in Medicina, 00186 Rome, Italy.
University of Pavia · ITOspedale Regina Margherita · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction. Recalcitrant skin ulcers are a major burden in elderly patients. Specifically, chronic wounds result in significant morbidity and mortality and have a profound economic impact. Pulsed electromagnetic fields (PEMFs) have proved to be a promising therapy for wound healing. Here we describe the first reported case of an innovative PEMF therapy, Emysimmetric Bilateral Stimulation (EBS), used to successfully treat refractory skin ulcers in two elderly and fragile patients. Case Presentation. Two elderly patients developed multiple chronic skin ulcerations. Despite appropriate treatment, the ulcers showed little improvement and the risk of amputation was high. Both patients underwent daily EBS therapy and standard dressing. After few weeks of treatment, major improvements were observed and all ulcers had healed. Conclusion. In patients with refractory ulceration, EBS therapy may be of real benefit in terms of faster healing. This case supports the supportive role for PEMFs in the treatment of skin ulceration in diabetes and is suggestive of a potential benefit of EBS in this clinical condition.

Identifiers

PMID26634159
PMCPMC4655025
OpenAlexW2122723124

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.