Evidence map›Paper›PMID 26633409›Full record

ReviewSensors (Basel, Switzerland)2015

Microfluidics Integrated Biosensors: A Leading Technology towards Lab-on-a-Chip and Sensing Applications.

George Luka, Ali Ahmadi, Homayoun Najjaran, Evangelyn Alocilja, Maria DeRosa, Kirsten Wolthers, Ahmed Malki, Hassan Aziz, Asmaa Althani, Mina Hoorfar

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 147 papers.

0numbers the graph read from it
0cells of the map it votes in
147citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

147 citing papers in PubMed.

  1. Review
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  4. From conventional to biosensor-based detection ofFood and waterborne parasitology · 2026
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87 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

George LukaSchool of Engineering, University of British Columbia, Kelowna, BC V1V 1V7, Canada. george.luka@ubc.ca.
Ali AhmadiSchool of Engineering, University of British Columbia, Kelowna, BC V1V 1V7, Canada. ali.ahmadi@ubc.ca.
Homayoun NajjaranSchool of Engineering, University of British Columbia, Kelowna, BC V1V 1V7, Canada. homayoun.najjaran@ubc.ca.
Evangelyn AlociljaNano-Biosensors Laboratory, Department of Biosystems and Agricultural Engineering, Michigan State University, 524 S. Shaw Lane, Room 115, East Lansing, MI 48224, USA. alocilja@msu.edu.
Maria DeRosaCarleton University, Department of Chemistry and Institute of Biochemistry, 225 Steacie Building 1125 Colonel By Drive Ottawa, ON K1S 5B6, Canada. maria_derosa@carleton.ca.
Kirsten WolthersSchool of Engineering, University of British Columbia, Kelowna, BC V1V 1V7, Canada. kirsten.wolthers@ubc.ca.
Ahmed MalkiDepartment of Health Sciences, College of Arts and Sciences, Qatar University, 2713 Doha, Qatar. ahmed.malki@qu.edu.qa.
Hassan AzizDepartment of Health Sciences, College of Arts and Sciences, Qatar University, 2713 Doha, Qatar. hassan.aziz@qu.edu.qa.
Asmaa AlthaniDepartment of Health Sciences, College of Arts and Sciences, Qatar University, 2713 Doha, Qatar. aaja@qu.edu.qa.
Mina HoorfarSchool of Engineering, University of British Columbia, Kelowna, BC V1V 1V7, Canada. mina.hoorfar@ubc.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A biosensor can be defined as a compact analytical device or unit incorporating a biological or biologically derived sensitive recognition element immobilized on a physicochemical transducer to measure one or more analytes. Microfluidic systems, on the other hand, provide throughput processing, enhance transport for controlling the flow conditions, increase the mixing rate of different reagents, reduce sample and reagents volume (down to nanoliter), increase sensitivity of detection, and utilize the same platform for both sample preparation and detection. In view of these advantages, the integration of microfluidic and biosensor technologies provides the ability to merge chemical and biological components into a single platform and offers new opportunities for future biosensing applications including portability, disposability, real-time detection, unprecedented accuracies, and simultaneous analysis of different analytes in a single device. This review aims at representing advances and achievements in the field of microfluidic-based biosensing. The review also presents examples extracted from the literature to demonstrate the advantages of merging microfluidic and biosensing technologies and illustrate the versatility that such integration promises in the future biosensing for emerging areas of biological engineering, biomedical studies, point-of-care diagnostics, environmental monitoring, and precision agriculture.

Indexed as

Biosensing TechniquesLab-On-A-Chip DevicesMicrofluidic Analytical Techniquesbiosensorlab-on-a-chipmicrofluidicmicrofluidic-based biosensormicro total analysis systems (μTAS)

Identifiers

PMID26633409
PMCPMC4721704

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.