ArticleMolecules (Basel, Switzerland)2015
Evaluation of Antimicrobial Efficiency of New Polymers Comprised by Covalently Attached and/or Electrostatically Bound Bacteriostatic Species, Based on Quaternary Ammonium Compounds.
Article in Molecules (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 39 citations in OpenAlex.
- Designing Antibacterial-Based Quaternary Ammonium Coatings (Surfaces) or Films for Biomedical Applications: Recent Advances.International journal of molecular sciences · 2024Review
- pH-Responsive Emission of Novel Water-Soluble Polymeric Iridium(III) Complexes.Nanomaterials (Basel, Switzerland) · 2022Article
- Multilayered Curcumin-Loaded Hydrogel Microcarriers with Antimicrobial Function.Molecules (Basel, Switzerland) · 2022Article
- Preparation of Antimicrobial Coatings from Cross-Linked Copolymers Containing Quaternary Dodecyl-Ammonium Compounds.International journal of molecular sciences · 2021Article
- Quaternary Ammonium Compounds (QACs) and Ionic Liquids (ILs) as Biocides: From Simple Antiseptics to Tunable Antimicrobials.International journal of molecular sciences · 2021Review
- Broad-Spectrum Bactericidal Activity of a Synthetic Random Copolymer Based on 2-Methoxy-6-(4-Vinylbenzyloxy)-Benzylammonium Hydrochloride.International journal of molecular sciences · 2021Article
- Environmentally Friendly Cross-Linked Antifouling Coatings Based on Dual Antimicrobial Action.International journal of molecular sciences · 2021Article
- Positively Charged Polymers as Promising Devices against Multidrug Resistant Gram-Negative Bacteria: A Review.Polymers · 2020Review
- Reduction in microbial survival on food contact surfaces by a spray coated polymerized quaternary ammonium compound.Food science & nutrition · 2020Article
- Polymeric Coatings Based on Water-Soluble Trimethylammonium Copolymers for Antifouling Applications.Molecules (Basel, Switzerland) · 2020Article
- Synthesis of Imidazolium based PILs and Investigation of Their Blend Membranes for Gas Separation.Membranes · 2019Article
- In vitro assessment of an antibacterial quaternary ammonium-based polymer loaded with chlorhexidine for the coating of polypropylene prosthetic meshes.Hernia : the journal of hernias and abdominal wall surgery · 2016Article
- Influences of Adhesion Variability on the "Living" Dynamics of Filamentous Bacteria in Microfluidic Channels.Molecules (Basel, Switzerland) · 2016Article
- Recent Developments in Antimicrobial Polymers: A Review.Materials (Basel, Switzerland) · 2016Review
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the present work a detailed study of new bacteriostatic copolymers with quaternized ammonium groups introduced in the polymer chain through covalent attachment or electrostatic interaction, was performed. Different copolymers have been considered since beside the active species, the hydrophobic/hydrophilic nature of the co-monomer was also evaluated in the case of covalently attached bacteriostatic groups, aiming at achieving permanent antibacterial activity. Homopolymers with quaternized ammonium/phosphonium groups were also tested for comparison reasons. The antimicrobial activity of the synthesized polymers after 3 and 24 h of exposure at 4 and 22 °C was investigated on cultures of Gram-negative (P. aeruginosa, E. coli) and Gram-positive (S. aureus, E. faecalis) bacteria. It was found that the combination of the hydrophilic monomer acrylic acid (AA), at low contents, with the covalently attached bacteriostatic group vinyl benzyl dimethylhexadecylammonium chloride (VBCHAM) in the copolymer P(AA-co-VBCHAM88), resulted in a high bacteriostatic activity against P. aeruginosa and E. faecalis (6 log reduction in certain cases). Moreover, the combination of covalently attached VBCHAM units with electrostatically bound cetyltrimethylammonium 4-styrene sulfonate (SSAmC16) units in the P(SSAmC16-co-VBCHAMx) copolymers led to efficient antimicrobial materials, especially against Gram-positive bacteria, where a log reduction between 4.9 and 6.2 was verified. These materials remain remarkably efficient even when they are incorporated in polysulfone membranes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.