ArticleJournal of perinatology : official journal of the California Perinatal Association2016
Cord blood telomere length in Latino infants: relation with maternal education and infant sex.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Leukocyte telomere length and obesity in children and adolescents: A systematic review and meta-analysis.Frontiers in genetics · 2022Pooled it
- Water, sanitation, handwashing, and nutritional interventions can reduce child antibiotic use: evidence from Bangladesh and Kenya.Nature communications · 2025Trial
- Effect of hypertensive disorders of pregnancy on outcome and relative telomere length in preterm infants.BMC pregnancy and childbirth · 2026Article
- Neighborhood built environment, psychosocial stressors, and telomere length of birth parents and their newborns from San Francisco, California.Journal of exposure science & environmental epidemiology · 2026Article
- Prenatal irisin is inversely related to the term placental telomere length.BMC research notes · 2025Article
- The Association Between Longer Maternal Leukocyte Telomere Length in the Immediate Postpartum Period and Preterm Birth in a Predominately Latina Cohort of Mothers.Maternal and child health journal · 2025Article
- High school diploma is associated with longer postpartum leukocyte telomere length in a cohort of primarily Latina women.Maternal health, neonatology and perinatology · 2024Article
- Preterm Birth and Its Association with Maternal Diet, and Placental and Neonatal Telomere Length.Nutrients · 2023Review
- Sub-optimal maternal gestational gain is associated with shorter leukocyte telomere length at birth in a predominantly Latinx cohort of newborns.Maternal health, neonatology and perinatology · 2023Article
- Interrelationships and determinants of aging biomarkers in cord blood.Journal of translational medicine · 2022Article
- Variability in newborn telomere length is explained by inheritance and intrauterine environment.BMC medicine · 2022Observational
- Prenatal exposure to maternal psychological distress and telomere length in childhood.Developmental psychobiology · 2022Article
- Longitudinal Follow-Up of Blood Telomere Length in HIV-Exposed Uninfected Children Having Received One Year of Lopinavir/Ritonavir or Lamivudine as Prophylaxis.Children (Basel, Switzerland) · 2021Article
- Maternal Vitamin D and Newborn Telomere Length.Nutrients · 2021Article
- Excess pregnancy weight gain in latinas: Impact on infant's adiposity and growth hormones at birth.Preventive medicine reports · 2021Article
- Obesity at Age 6 Months Is Associated with Shorter Preschool Leukocyte Telomere Length Independent of Parental Telomere Length.The Journal of pediatrics · 2021Article
- Maternal overweight but not paternal overweight before pregnancy is associated with shorter newborn telomere length: evidence from Guangxi Zhuang birth cohort in China.BMC pregnancy and childbirth · 2021Article
- Maternal psychosocial functioning, obstetric health history, and newborn telomere length.Psychoneuroendocrinology · 2021Article
- Pregnancy by Assisted Reproductive Technology Is Associated with Shorter Telomere Length in Neonates.International journal of molecular sciences · 2020Article
- The metabolic syndrome in pregnancy and its association with child telomere length.Diabetologia · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectiveTelomere length (TL) has important consequences for early disease and lifelong health. However, few studies have examined determinants of TL at birth. STUDY
designHere we test associations between cord blood TL and parental and birth factors associated with exposure to stress and indicative of healthy intrauterine life in Latino infants. We tested associations that were significant in bivariate analysis in a multivariate regression model to identify independent predictors for shorter TL at birth.
resultTwo novel and independent predictors emerged in our analysis of 54 infants. Female gender was associated with longer TL by ~350 base pairs (adjusted β-coefficient for male gender=-369.57, (95% confidence interval, -718.21 to (-)20.92), P=0.02); rho=-0.26, P=0.057). Increased maternal high-school education, as indicated by a high-school diploma or additional education beyond high school, was also associated with longer TL, by ~500 base pairs (adjusted β-coefficient for high-school diploma or greater=505.68 (95% confidence interval, 151.69 to 859.68), P<0.01); rho=0.36, P<0.01). Increasing head circumference trended towards statistical significance in association with longer TL (adjusted β-coefficient = 7.33; 95% confidence interval -0.52 to 15.18; P=0.07). When we removed all infants who had been exposed to high oxidative stress in pregnancy including those exposed to maternal hypertension, preeclampsia, gestational diabetes, and those who were low birth weight or preterm birth (n=7), increasing birth weight percentile was associated with longer TL (adjusted β-coefficient=8.04 (95% confidence interval 0.07 to 16.00), P=0.048).
conclusionShorter TL at birth is associated with being male, low maternal education (less than a high school degree), and a trend towards lower birth weight and head circumference. Given the critical role of long TL in predicting health and disease, these findings contribute to the growing literature attempting to understand determinants of TL.
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