ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2015
Characterization of Train-Induced Vibration and its Effect on Fecal Corticosterone Metabolites in Mice.
Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Lockbox enrichment facilitates manipulative and cognitive activities for mice.Open research Europe · 2024Article
- Sonic vibration ameliorates inflammatory diseases via the up-regulation of IL-10.Animal cells and systems · 2024Article
- A Review of the Effects of Some Extrinsic Factors on Mice Used in Research.Comparative medicine · 2023Review
- Evaluation of Ambient Sound, Vibration, and Light in Rodent Housing Rooms.Journal of the American Association for Laboratory Animal Science : JAALAS · 2022Article
- The rat Lux Actuating Search Task (LAST) and effects of sleep deprivation on task reversal performance.Neurobiology of sleep and circadian rhythms · 2022Article
- Introduction to Environmental Harmful Factors.Advances in experimental medicine and biology · 2021Article
- Noise and Vibration in the Vivarium: Recommendations for Developing a Measurement Plan.Journal of the American Association for Laboratory Animal Science : JAALAS · 2020Article
- The Impact of Acute Loud Noise on the Behavior of Laboratory Birds.Frontiers in veterinary science · 2020Article
- Immune Relevant and Immune Deficient Mice: Options and Opportunities in Translational Research.ILAR journal · 2018Review
- Vibration-induced Behavioral Responses and Response Threshold in Female C57BL/6 Mice.Journal of the American Association for Laboratory Animal Science : JAALAS · 2018Article
- Vibration in mice: A review of comparative effects and use in translational research.Animal models and experimental medicine · 2018Review
- Systematic Assessment of Well-Being in Mice for Procedures Using General Anesthesia.Journal of visualized experiments : JoVE · 2018Article
- Impact of repeated anesthesia with ketamine and xylazine on the well-being of C57BL/6JRj mice.PloS one · 2018Article
- Severity classification of repeated isoflurane anesthesia in C57BL/6JRj mice-Assessing the degree of distress.PloS one · 2017Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Excessive environmental vibrations can have deleterious effects on animal health and experimental results, but they remain poorly understood in the animal laboratory setting. The aims of this study were to characterize train-associated vibration in a rodent vivarium and to assess the effects of this vibration on the reproductive success and fecal corticosterone metabolite levels of mice. An instrumented cage, featuring a high-sensitivity microphone and accelerometer, was used to characterize the vibrations and sound in a vivarium that is near an active railroad. The vibrations caused by the passing trains are 3 times larger in amplitude than are the ambient facility vibrations, whereas most of the associated sound was below the audible range for mice. Mice housed in the room closest to the railroad tracks had pregnancy rates that were 50% to 60% lower than those of mice of the same strains but bred in other parts of the facility. To verify the effect of the train vibrations, we used a custom-built electromagnetic shaker to simulate the train-induced vibrations in a controlled environment. Fecal pellets were collected from male and female mice that were exposed to the simulated vibrations and from unexposed control animals. Analysis of the fecal samples revealed that vibrations similar to those produced by a passing train can increase the levels of fecal corticosterone metabolites in female mice. These increases warrant attention to the effects of vibration on mice and, consequently, on reproduction and experimental outcomes.
Indexed as
Identifiers
26632783PMC4671789What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.