ArticleMedicine2015
High Blood Pressure and All-Cause and Cardiovascular Disease Mortalities in Community-Dwelling Older Adults.
Article in Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
87 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Predictors of major adverse cardiac and cerebrovascular events after percutaneous coronary intervention in older adults: a systematic review and meta-analysis.BMC geriatrics · 2024Pooled it
- The Effect of Non-Oil Seed Legume Intake on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Advances in nutrition (Bethesda, Md.) · 2023Pooled it
- A systematic review and meta-analysis of the effects of Hibiscus sabdariffa on blood pressure and cardiometabolic markers.Nutrition reviews · 2022Pooled it
- Effects of qigong on systolic and diastolic blood pressure lowering: a systematic review with meta-analysis and trial sequential analysis.BMC complementary medicine and therapies · 2021Pooled it
- Change in cascade of care among individuals with hypertension - India hypertension control initiative, 2018-2024.American journal of preventive cardiology · 2026Article
- Predictors of Short- and Long-Term Major Adverse Cardiac and Cerebrovascular Events (MACCE) After Percutaneous Coronary Intervention: A Cohort Study on the Data of National Persian Registry of Cardiovascular Disease (N-PROVE).Health science reports · 2026Article
- PPG-Based Heart Rate Accuracy in Hispanic Adults with Fitzpatrick III-V Skin Tones: An Evaluation of Body Composition and Skin-Tone Effects.Sensors (Basel, Switzerland) · 2026Article
- Joint associations between exercising and classical cardiometabolic risk factors with all-cause, premature and cardiovascular mortality: a prospective cohort study among Mexican adults.Frontiers in endocrinology · 2026Article
- Increased dairy product consumption is associated with shorter telomere length in buccal cells among normotensive adults.BioMedicine · 2026Article
- Structural and Computational Insights into the Angiotensin II Type 1 Receptor: Advances in Antagonist Design and Implications for Hypertension Therapy (2020-2024).Biomolecules · 2025Review
- Adherence to the European Society of Cardiology hypertension guidelines over 12 years of follow-up in the Irish population.Open heart · 2025Article
- Unlocking Novel Therapeutic Potential of Angiotensin II Receptor Blockers.International journal of molecular sciences · 2025Review
- Wearable blood pressure sensors for cardiovascular monitoring and machine learning algorithms for blood pressure estimation.Nature reviews. Cardiology · 2025Review
- Relationship Between Simple Renal Cysts and Hypertension: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- FFA Patient Profile Analysis Based on the Authors' Observations and a Review of the Literature-An Original Survey.Journal of clinical medicine · 2025Article
- Blood pressure regulation through circadian variation: PRDM16 as a target in vascular smooth muscle cells.The Journal of clinical investigation · 2025Article
- Association between chronic fatigue syndrome/myalgic encephalomyelitis and cardiovascular disease.Scientific reports · 2025Article
- Prevalence and factors associated with poor sleep quality among patients with hypertension in a primary care clinic: A cross-sectional study.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2025Article
- Alleviating the public health burden of hypertension: debating precision prevention as a possible solution.Global health action · 2024Article
- Zero End-Digit Preference in Blood Pressure and Implications for Cardiovascular Disease Risk Prediction-A Study in New Zealand.Journal of clinical medicine · 2024Article
27 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although hypertension is common among older adults, the optimal blood pressure (BP) for survival in older adults remains unclear. We attempt to use a large cohort to assess the relationship between BP and mortality and to gain insight into what level of BP is required for optimal survival in older adults.A total of 77,389 community-dwelling adults, aged ≥65 years, were followed between 2006 and 2010. Mortality was determined using matching cohort identifications with national death files. Cox proportional hazards regression models were used to evaluate the relationship of BP with all-cause, cardiovascular disease (CVD), and expanded-CVD mortalities.The mortality risks of the stage 2-3 hypertension group were substantial (all-cause mortality: hazard ratio [HR]: 1.23; 95% confidence interval [CI]: 1.10-1.37; CVDs mortality: HR: 1.31; 95% CI: 1.05-1.64; expanded-CVDs mortality: HR: 1.40; 95% CI: 1.15-1.71). The cardiovascular and expanded-cardiovascular mortality risks were lowest when systolic blood pressures were 120 to 129 mm Hg, and increased significantly when systolic blood pressures (SBPs) were ≥160 mm Hg or diastolic BPs were ≥90 mm Hg. A J-curve phenomenon for SBP on CVD and expanded-CVD mortality was observed. The impacts of stage 2-3 hypertension on mortality risks were significantly increased among women. The mortality risks of hypertension were not attenuated with older age.This study provides insight for identifying the optimal BP for survival in older adults, and extends the knowledge of the impacts of hypertension on mortality risks among women and the older adults.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.