Evidence map›Paper›PMID 26632728›Full record

ArticleMedicine2015

Organophosphate Poisoning and Subsequent Acute Kidney Injury Risk: A Nationwide Population-Based Cohort Study.

Feng-You Lee, Wei-Kung Chen, Cheng-Li Lin, Ching-Yuan Lai, Yung-Shun Wu, I-Ching Lin, Chia-Hung Kao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
7.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Molecular Mechanisms of Acute Organophosphate Nephrotoxicity.International journal of molecular sciences · 2022
    Review
  7. Acute Kidney Failure among Brazilian Agricultural Workers: A Death-Certificate Case-Control Study.International journal of environmental research and public health · 2022
    Article
  8. Article
  9. Article
  10. Nephrotoxic Effects of Paraoxon in Three Rat Models of Acute Intoxication.International journal of molecular sciences · 2021
    Article
  11. Review
  12. Immunotoxic role of organophosphates: An unseen risk escalating SARS-CoV-2 pathogenicity.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2021
    Review
  13. Observational
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Feng-You LeeFrom the Department of Emergency Medicine (F-YL), Taichung Tzu Chi Hospital; Department of Emergency Medicine (W-KC, C-YL), Trauma and Emergency Center; Management Office for Health Data (C-LL), China Medical University Hospital; College of Medicine (C-LL), China Medical University, Taichung; Department of Emergency Medicine (Y-SW), Hualien Armed Forces General Hospital, Hualien; Family Medicine Department (I-CL), Changhua Christian Hospital, Changhua; School of Medicine (I-CL), Kaohsiung Medical University, Kaohsiung; School of Medicine (I-CL), Chung Shan Medical University; Graduate Institute of Clinical Medical Science (C-HK), China Medical University; and Department of Nuclear Medicine and PET Center (C-HK), China Medical University Hospital, Taichung, Taiwan.
Wei-Kung Chen
Cheng-Li Lin
Ching-Yuan Lai
Yung-Shun Wu
I-Ching Lin
Chia-Hung Kao
Bridge University · SSChina Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small numbers of the papers have studied the association between organophosphate (OP) poisoning and the subsequent acute kidney injury (AKI). Therefore, we used the National Health Insurance Research Database (NHIRD) to study whether patients with OP poisoning are associated with a higher risk to have subsequent AKI.The retrospective cohort study comprised patients aged ≥20 years with OP poisoning and hospitalized diagnosis during 2000-2011 (N = 8924). Each OP poisoning patient was frequency-matched to 4 control patients based on age, sex, index year, and comorbidities of diabetes, hypertension, hyperlipidemia, chronic obstructive pulmonary disease, coronary artery disease, and stroke (N = 35,696). We conducted Cox proportional hazard regression analysis to estimate the effects of OP poisoning on AKI risk.The overall incidence of AKI was higher in the patients with OP poisoning than in the controls (4.85 vs 3.47/1000 person-years). After adjustment for age, sex, comorbidity, and interaction terms, patients with OP poisoning were associated with a 6.17-fold higher risk of AKI compared with the comparison cohort. Patients with highly severe OP poisoning were associated with a substantially increased risk of AKI.The study found OP poisoning is associated with increased risk of subsequent AKI. Future studies are encouraged to evaluate whether long-term effects exist and the best guideline to prevent the continuously impaired renal function.

Indexed as

Acute Kidney InjuryAdultAgedComorbidityFemaleHumansIncidenceMaleMiddle AgedOrganophosphate PoisoningProportional Hazards ModelsRetrospective StudiesRisk FactorsSeverity of Illness Index

Identifiers

PMID26632728
PMCPMC5058997
OpenAlexW2315199989

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.