Trial reportAmerican journal of Alzheimer's disease and other dementias2016
Multisensory Stimulation as an Intervention Strategy for Elderly Patients With Severe Dementia: A Pilot Randomized Controlled Trial.
Trial report in American journal of Alzheimer's disease and other dementias, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- [Therapy strategies for repetitive vocalizations in dementia : A systematic review].Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2025Pooled it
- Pooled it
- Multisensory stimulation reduces neuropsychiatric symptoms and enhances cognitive function in older adults with dementia: A meta-analysis of randomized controlled trials.The journal of prevention of Alzheimer's disease · 2025Pooled it
- Personally tailored activities for improving psychosocial outcomes for people with dementia in long-term care.The Cochrane database of systematic reviews · 2023Pooled it
- Effectiveness of treatments for people living with severe dementia: A systematic review and meta-analysis of randomised controlled clinical trials.Ageing research reviews · 2022Pooled it
- Person-Centered Care in Persons Living With Dementia: A Systematic Review and Meta-analysis.The Gerontologist · 2022Pooled it
- Personally tailored activities for improving psychosocial outcomes for people with dementia in long-term care.The Cochrane database of systematic reviews · 2018Pooled it
- Optimal nonpharmacological management of agitation in Alzheimer's disease: challenges and solutions.Clinical interventions in aging · 2016Pooled it
- The Combined Effect of Multisensory Stimulation and Therapist Support on Physical and Mental Health of Older Adults Living in Nursing Homes: Pilot Randomized Controlled Trial.Journal of medical Internet research · 2025Trial
- Non-Pharmacological Interventions for Managing Apathy in Older Adults with Neurocognitive Disorders: A Systematic Review of Randomized Controlled Trials.Brain sciences · 2026Review
- Multisensory Stimulation in Rehabilitation of Dementia: A Systematic Review.Biomedicines · 2025Review
- Organizational characteristics of highly specialized units for people with dementia and severe challenging behavior.BMC geriatrics · 2024Article
- Sensory Integration: A Novel Approach for Healthy Ageing and Dementia Management.Brain sciences · 2024Review
- Can Virtual Reality Help Improve Motor and Cognitive Function in Active Aging in Older Adults? A Scoping Review.Healthcare (Basel, Switzerland) · 2024Article
- Snoezelen in people with intellectual disability or dementia: A systematic review.International journal of nursing studies advances · 2023Review
- Diagnostic criteria for apathy in neurocognitive disorders.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021Article
- A Novel Intervention for Management of Behavioral and Psychological Symptoms of Dementia in Nursing Home Communal Areas: Results of a Small-Scale Pilot Trial.Journal of Alzheimer's disease reports · 2021Article
- The Hyperactivity-Impulsivity-Irritiability-Disinhibition-Aggression-Agitation Domain in Alzheimer's Disease: Current Management and Future Directions.Frontiers in pharmacology · 2019Review
- Creating objects with 3D printers to stimulate reminiscence in memory loss: A mixed-method feasibility study.Informatics for health & social care · 2018Article
- Psychosocial and Environmental Treatment Approaches for Behavioral and Psychological Symptoms in Neurocognitive Disorders: an Update and Future Directions.Current treatment options in psychiatry · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this study was to compare the effect of multisensory stimulation environment (MSSE) and one-to-one activity sessions in the symptomatology of elderly individuals with severe dementia. Thirty-two participants were randomly assigned to the following 3 groups: MSSE, activity, and control group. The MSSE and activity groups participated in two 30-minute weekly sessions over 16 weeks. Pre-, mid-, and posttrial; 8-week follow-up behavior; mood; cognitive status; and dementia severity were registered. Patients in the MSSE group demonstrated a significant improvement in the Neuropsychiatric Inventory and Bedford Alzheimer Nursing Severity Scale scores compared with the activity group. Both MSSE and activity groups showed an improvement during the intervention in the Cohen-Mansfield Agitation Inventory aggressive behavior factor and total score, with no significant differences between groups. The MSSE may have better effects on neuropsychiatric symptoms and dementia severity in comparison with one-to-one activity sessions in patients with severe dementia.
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Registered trials
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