ArticleEndocrine connections2016
Lower fasting blood glucose in neurofibromatosis type 1.
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Article in Endocrine connections, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15citing papers in PubMed
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Who cites it
15 citing papers in PubMed, 27 citations in OpenAlex.
- Metabolic and behavioral effects of neurofibromin result from differential recruitment of MAPK and mTOR signaling.PLoS genetics · 2026Article
- Loss of neurofibromin induces inflammatory macrophage phenotypic switch and retinal neovascularization via GLUT1 activation.Cell reports · 2025Article
- Anthropometric measurements of children with neurofibromatosis type I: impact of plexiform neurofibroma volume and treatment.Pediatric research · 2025Article
- Beyond Hypertension: Hypoglycemia as an Atypical Presentation of Pheochromocytoma in Neurofibromatosis Type 1.Cureus · 2025Article
- Unraveling neuronal and metabolic alterations in neurofibromatosis type 1.Journal of neurodevelopmental disorders · 2024Review
- Biomarker Landscape in RASopathies.International journal of molecular sciences · 2024Review
- Persistent level 1 hypoglycemia due to hypothyroidism and underlying Neurofibromatosis type 1.Clinical case reports · 2023Article
- Splicing annotation of endometrial cancer GWAS risk loci reveals potentially causal variants and supports a role forHGG advances · 2023Article
- Head circumference and anthropometric changes and their relation to plexiform and skin neurofibromas in sporadic and familial neurofibromatosis 1 Brazilian adults: a cross-sectional study.Orphanet journal of rare diseases · 2022Article
- Neurofibromin regulates metabolic rate via neuronal mechanisms in Drosophila.Nature communications · 2021Article
- Haploinsufficiency of theJournal of medical genetics · 2021Article
- Multisystem burden of neurofibromatosis 1 in Denmark: registry- and population-based rates of hospitalizations over the life span.Genetics in medicine : official journal of the American College of Medical Genetics · 2020Article
- Association of interleukin-18 gene polymorphism and its protein expression with the lower extremity deep venous thrombosis in the chinese han population: A case-control study.Journal of clinical laboratory analysis · 2018Article
- Increased insulin sensitivity in individuals with neurofibromatosis type 1.Archives of endocrinology and metabolism · 2018Article
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Authors and funding
11 authors at 1 institution in 1 country.
Aline Stangherlin MartinsNeurofibromatosis Outpatient Reference CenterFederal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, BrazilDepartment of Nutrition, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Medical Clinic, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Preventive and Social Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Internal Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilThe Neurofibromatosis Institute5415 Briggs Avenue, La Crescenta, CA, USA.
Ann Kristine JansenNeurofibromatosis Outpatient Reference CenterFederal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, BrazilDepartment of Nutrition, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Medical Clinic, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Preventive and Social Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Internal Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilThe Neurofibromatosis Institute5415 Briggs Avenue, La Crescenta, CA, USA.
Luiz Oswaldo Carneiro RodriguesNeurofibromatosis Outpatient Reference CenterFederal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, BrazilDepartment of Nutrition, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Medical Clinic, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Preventive and Social Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Internal Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilThe Neurofibromatosis Institute5415 Briggs Avenue, La Crescenta, CA, USA.
Camila Maria MatosNeurofibromatosis Outpatient Reference CenterFederal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, BrazilDepartment of Nutrition, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Medical Clinic, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Preventive and Social Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Internal Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilThe Neurofibromatosis Institute5415 Briggs Avenue, La Crescenta, CA, USA.
Marcio Leandro Ribeiro SouzaNeurofibromatosis Outpatient Reference CenterFederal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, BrazilDepartment of Nutrition, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Medical Clinic, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Preventive and Social Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Internal Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilThe Neurofibromatosis Institute5415 Briggs Avenue, La Crescenta, CA, USA.
Juliana Ferreira de SouzaNeurofibromatosis Outpatient Reference CenterFederal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, BrazilDepartment of Nutrition, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Medical Clinic, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Preventive and Social Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Internal Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilThe Neurofibromatosis Institute5415 Briggs Avenue, La Crescenta, CA, USA.
Maria de Fátima Haueisen Sander DinizNeurofibromatosis Outpatient Reference CenterFederal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, BrazilDepartment of Nutrition, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Medical Clinic, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Preventive and Social Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Internal Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilThe Neurofibromatosis Institute5415 Briggs Avenue, La Crescenta, CA, USA.
Sandhi Maria BarretoNeurofibromatosis Outpatient Reference CenterFederal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, BrazilDepartment of Nutrition, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Medical Clinic, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Preventive and Social Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Internal Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilThe Neurofibromatosis Institute5415 Briggs Avenue, La Crescenta, CA, USA.
Leonardo Mauricio DinizNeurofibromatosis Outpatient Reference CenterFederal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, BrazilDepartment of Nutrition, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Medical Clinic, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Preventive and Social Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Internal Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilThe Neurofibromatosis Institute5415 Briggs Avenue, La Crescenta, CA, USA.
Nilton Alves de RezendeNeurofibromatosis Outpatient Reference CenterFederal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, BrazilDepartment of Nutrition, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Medical Clinic, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Preventive and Social Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Internal Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilThe Neurofibromatosis Institute5415 Briggs Avenue, La Crescenta, CA, USA Neurofibromatosis Outpatient Reference CenterFederal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, BrazilDepartment of Nutrition, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Medical Clinic, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Preventive and Social Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Internal Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilThe Neurofibromatosis Institute5415 Briggs Avenue, La Crescenta, CA, USA narezende@terra.com.br.
Vincent Michael RiccardiNeurofibromatosis Outpatient Reference CenterFederal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, BrazilDepartment of Nutrition, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Medical Clinic, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Preventive and Social Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilDepartment of Internal Medicine, Federal University of Minas GeraisProfessor Alfredo Balena Avenue, 190, Santa Efigênia, Belo Horizonte, Minas Gerais, BrazilThe Neurofibromatosis Institute5415 Briggs Avenue, La Crescenta, CA, USA.
Universidade Federal de Minas Gerais · BR
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies indicate a lower occurrence of diabetes mellitus (DM) in patients with neurofibromatosis type 1 (NF1). Fasting blood glucose (FBG) level is the main criterion used to diagnose DM and glucose intolerance. Therefore, this study compared FBG level between adults with NF1 and non-NF1 controls. We selected clinical records of 57 out of 701 individuals attending the Neurofibromatosis Outpatient Reference Center of the Clinics Hospital of the Federal University of Minas Gerais in Brazil. The selected patients with NF1 were matched to non-NF1 controls selected from the Brazilian Longitudinal Study of Adult Health according to sex, age (range, 35-74 years) and BMI at a ratio of 1:3. In both groups, individuals with DM were excluded. Median FBG level in the NF1 group (86 mg/dl (range, 56-127 mg/dl)) was lower than that in the non-NF1 control group (102 mg/dl (range, 85-146 mg/dl)) (P<0.001). Prevalence of FBG level ≥100 mg/dl in the NF1 group (16%) was lower than that in the non-NF1 control group (63%) (P<0.05). The chance of a high FBG level was 89% lower in the NF1 group (odds ratio, 0.112; 95% CI, 0.067-0.188) (P<0.05). In conclusion, adults with NF1 showed a lower FBG level and a lower prevalence of high FBG level compared with non-NF1 controls.
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fasting blood glucoseinsulin resistanceneurofibromatosis type 1nutritional statustype 2 diabetes mellitus
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