Evidence map›Paper›PMID 26631333›Full record

ArticleJournal of the Royal Society, Interface2015

The microscopic network structure of mussel (Mytilus) adhesive plaques.

Emmanouela Filippidi, Daniel G DeMartini, Paula Malo de Molina, Eric W Danner, Juntae Kim, Matthew E Helgeson, J Herbert Waite, Megan T Valentine

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Royal Society, Interface, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Investigating byssus self-assembly ofMarine life science & technology · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Force distribution and multiscale mechanics in the mussel byssus.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Mussel adhesion - essential footwork.The Journal of experimental biology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Emmanouela FilippidiMaterials Research Laboratory, University of California Santa Barbara, Santa Barbara, CA, USA.ORCID http://orcid.org/0000-0002-4044-0022
Daniel G DeMartiniMolecular, Cellular and Developmental Biology, University of California Santa Barbara, Santa Barbara, CA, USA.
Paula Malo de MolinaChemical Engineering, University of California Santa Barbara, Santa Barbara, CA, USA.ORCID http://orcid.org/0000-0002-9911-5320
Eric W DannerBiomolecular Science and Engineering, University of California Santa Barbara, Santa Barbara, CA, USA.ORCID http://orcid.org/0000-0003-4630-1100
Juntae KimChemical Engineering, University of California Santa Barbara, Santa Barbara, CA, USA.ORCID http://orcid.org/0000-0002-1319-3521
Matthew E HelgesonChemical Engineering, University of California Santa Barbara, Santa Barbara, CA, USA.ORCID http://orcid.org/0000-0001-9384-4023
J Herbert WaiteMaterials Research Laboratory, University of California Santa Barbara, Santa Barbara, CA, USA Molecular, Cellular and Developmental Biology, University of California Santa Barbara, Santa Barbara, CA, USA Biomolecular Science and Engineering, University of California Santa Barbara, Santa Barbara, CA, USA.
Megan T ValentineMaterials Research Laboratory, University of California Santa Barbara, Santa Barbara, CA, USA Mechanical Engineering, University of California Santa Barbara, Santa Barbara, CA, USA valentine@engineering.ucsb.edu.ORCID http://orcid.org/0000-0003-4781-8478

Funding

Translating Mussel AdhesionR01DE018468 · NIDCR · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI WAITE, JOHN HERBERT · 2008 to 2017
$4.2M
NIDCR NIH HHS R01 DE018468NIDCR NIH HHS R01-DE018468
6 · The paper itself

Abstract

Marine mussels of the genus Mytilus live in the hostile intertidal zone, attached to rocks, bio-fouled surfaces and each other via collagen-rich threads ending in adhesive pads, the plaques. Plaques adhere in salty, alkaline seawater, withstanding waves and tidal currents. Each plaque requires a force of several newtons to detach. Although the molecular composition of the plaques has been well studied, a complete understanding of supra-molecular plaque architecture and its role in maintaining adhesive strength remains elusive. Here, electron microscopy and neutron scattering studies of plaques harvested from Mytilus californianus and Mytilus galloprovincialis reveal a complex network structure reminiscent of structural foams. Two characteristic length scales are observed characterizing a dense meshwork (approx. 100 nm) with large interpenetrating pores (approx. 1 µm). The network withstands chemical denaturation, indicating significant cross-linking. Plaques formed at lower temperatures have finer network struts, from which we hypothesize a kinetically controlled formation mechanism. When mussels are induced to create plaques, the resulting structure lacks a well-defined network architecture, showcasing the importance of processing over self-assembly. Together, these new data provide essential insight into plaque structure and formation and set the foundation to understand the role of plaque structure in stress distribution and toughening in natural and biomimetic materials.

Indexed as

AnimalsAnimal StructuresMytiluselectron microscopymusselsMytilusplaquessmall-angle neutron scattering

Identifiers

PMID26631333
PMCPMC4707855

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.