Evidence map›Paper›PMID 26631296›Full record

ArticleBMJ (Clinical research ed.)2015

Association of hip pain with radiographic evidence of hip osteoarthritis: diagnostic test study.

Chan Kim, Michael C Nevitt, Jingbo Niu, Mary M Clancy, Nancy E Lane, Thomas M Link, Steven Vlad, Irina Tolstykh, Pia M Jungmann, David T Felson and 1 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in BMJ (Clinical research ed.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 10 pooled it
11.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 10 syntheses or guidelines pooled it, 170 citations in OpenAlex.

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  14. The clinical utility of imaging in osteoarthritis and its importance in future prediction of total hip replacement; a nested case-control study within the AGES-Reykjavik cohort.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026
    Article
  15. The invisible hip: radiographic "misses" in hip-spine syndrome and the diagnostic disparity between orthopedic surgeons and neurosurgeons.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Chan KimClinical Epidemiology Research and Training Unit, Boston University School of Medicine, 650 Albany St, Room X200, Boston, MA 02116, USA Department of Rheumatology, Boston University School of Medicine, Boston, MA, USA bevochan@bu.edu.
Michael C NevittDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
Jingbo NiuClinical Epidemiology Research and Training Unit, Boston University School of Medicine, 650 Albany St, Room X200, Boston, MA 02116, USA.
Mary M ClancyClinical Epidemiology Research and Training Unit, Boston University School of Medicine, 650 Albany St, Room X200, Boston, MA 02116, USA.
Nancy E LaneDepartment of Rheumatology, University of California, Davis, CA, USA.
Thomas M LinkDepartment of Rheumatology, University of California, San Francisco, CA, USA.
Steven VladDepartment of Rheumatology, Tufts Medical Center, Boston, MA, USA.
Irina TolstykhDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
Pia M JungmannDepartment of Diagnostic and Interventional Radiology, Technische Universität München, Munich, Germany.
David T FelsonClinical Epidemiology Research and Training Unit, Boston University School of Medicine, 650 Albany St, Room X200, Boston, MA 02116, USA NIHR Manchester Biomedical Research Unit, Manchester, UK.
Ali GuermaziDepartment of Radiology, Boston University School of Medicine, Boston, MA, USA.
Boston University · USUniversity of California, San Francisco · USTechnical University of Munich · DETufts Medical Center · USUniversity of California, Davis · US

Funding

WORK DISABILITY-- PERSONS WITH RHEUMATOID ARTHRITISP60AR047785 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI FELSON, DAVID TOBIN · 2001 to 2016
$18.0M
THE FRAMINGHAM OSTEOARTHRITIS STUDYR01AG018393 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI FELSON, DAVID TOBIN · 2000 to 2005
$4.8M
CLINICAL CENTERS FOR THE OSTEOARTHRITIS INITIATIVE-N01AR22260N01AR022260 · NIAMS · UNIVERSITY OF PITTSBURGH · PI KWOH, KENT · 2002 to 2006
–
DATA COORDINATING CENTER FOR THE OSTEOARTHRITIS INITIATIVE-264022258N01AR022258 · NIAMS · UNIVERSITY OF CALIFORNIA SYS OFFICE/PRES · 2003 to 2003
–
CLINICAL CENTER FOR THE OSTEOARTHRITIS-264022262-264022262N01AR022262 · NIAMS · THE MEMORIAL HOSPITAL · PI ASSAF, ANNLOUISE R. · 2002 to 2006
–
CLINICAL CENTERS FOR THE OSTEOARTHRITIS INITIATIVE-N01AR22261N01AR022261 · NIAMS · OHIO STATE UNIVERSITY RESEARCH · PI JACKSON, REBECCA · 2002 to 2006
–
CLINICAL CENTERS FOR THE OSTEOARTHRITIS INITIATIVE-264022259-264022259N01AR022259 · NIAMS · UNIVERSITY OF MARYLAND AT BALT · PI HOCHBERG, MARC C. · 2002 to 2006
–
NIAMS NIH HHS AR47785NIAMS NIH HHS N01-AR-2-2258NIAMS NIH HHS N01-AR-2-2259NIAMS NIH HHS N01-AR-2-2260NIAMS NIH HHS N01-AR-2-2261NIAMS NIH HHS N01-AR-2-2262NIAMS NIH HHS NIH AR47785NIAMS NIH HHS P60 AR047785NIA NIH HHS AG18393PHS HHS HHSN268201000019C
6 · The paper itself

Abstract

study questionIs there concordance between hip pain and radiographic hip osteoarthritis?

methodsIn this diagnostic test study, pelvic radiographs were assessed for hip osteoarthritis in two cohorts: the Framingham Osteoarthritis Study (community of Framingham, Massachusetts) and the Osteoarthritis Initiative (a multicenter longitudinal cohort study of osteoarthritis in the United States). Using visual representation of the hip joint, participants reported whether they had hip pain on most days and the location of the pain: anterior, groin, lateral, buttocks, or low back. In the Framingham study, participants with hip pain were also examined for hip pain with internal rotation. The authors analysed the agreement between radiographic hip osteoarthritis and hip pain, and for those with hip pain suggestive of hip osteoarthritis they calculated the sensitivity, specificity, positive predictive value, and negative predictive value of radiographs as the diagnostic test. STUDY ANSWER AND LIMITATIONS: In the Framingham study (n=946), only 15.6% of hips in patients with frequent hip pain showed radiographic evidence of hip osteoarthritis, and 20.7% of hips with radiographic hip osteoarthritis were frequently painful. The sensitivity of radiographic hip osteoarthritis for hip pain localised to the groin was 36.7%, specificity 90.5%, positive predictive value 6.0%, and negative predictive value 98.9%. Results did not differ much for hip pain at other locations or for painful internal rotation. In the Osteoarthritis Initiative study (n=4366), only 9.1% of hips in patients with frequent pain showed radiographic hip osteoarthritis, and 23.8% of hips with radiographic hip osteoarthritis were frequently painful. The sensitivity of definite radiographic hip osteoarthritis for hip pain localised to the groin was 16.5%, specificity 94.0%, positive predictive value 7.1%, and negative predictive value 97.6%. Results also did not differ much for hip pain at other locations. WHAT THIS STUDY ADDS: Hip pain was not present in many hips with radiographic osteoarthritis, and many hips with pain did not show radiographic hip osteoarthritis. Most older participants with a high suspicion for clinical hip osteoarthritis (groin or anterior pain and/or painful internal rotation) did not have radiographic hip osteoarthritis, suggesting that in many cases, hip osteoarthritis might be missed if diagnosticians relied solely on hip radiographs. FUNDING, COMPETING INTERESTS, DATA SHARING: See the full paper on thebmj.com for funding. The authors have no competing interests. Additional data are available from bevochan@bu.edu.

Indexed as

AgedAged, 80 and overArthralgiaCohort StudiesFemaleHumansMaleMiddle AgedOsteoarthritis, HipPredictive Value of TestsPrevalenceRadiographyRisk FactorsUnited KingdomUnited States

Identifiers

PMID26631296
PMCPMC4667842
OpenAlexW2183614706

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.