Evidence map›Paper›PMID 26631262›Full record

ReviewItalian journal of pediatrics2015

Paediatric arterial ischemic stroke: acute management, recent advances and remaining issues.

Margherita Rosa, Silvana De Lucia, Victoria Elisa Rinaldi, Julie Le Gal, Marie Desmarest, Claudio Veropalumbo, Silvia Romanello, Luigi Titomanlio

Open access · goldAbstract readReview
In one paragraph

Review in Italian journal of pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. A case of symmetric retrograde thromboembolic cerebral infarction in an 8-year-old child due to arterial thoracic outlet syndrome.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018
    Article
  7. Moyamoya disease in a Moroccan baby: a case report.Journal of medical case reports · 2018
    Article
  8. Risk Factors of Pediatric Arterial Ischemic Stroke; A Regional Survey.International journal of preventive medicine · 2018
    Article
  9. Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Margherita RosaDepartment of Translational Medicine-Section of Pediatrics, Federico II University, Naples, Italy. margherita.rosa@hotmail.it.
Silvana De LuciaDepartment of Paediatrics, Aldo Moro University of Bari, Bari, Italy. silvidelucia@hotmail.it.
Victoria Elisa RinaldiDepartment of Paediatrics, University of Perouse, Perugia, Italy. victoria.rinaldi87@gmail.com.
Julie Le GalPaediatric Migraine & Neurovascular diseases Unit, Department of Paediatrics, Robert Debré Hospital, Paris Diderot University, Sorbonne Paris Cité, Paris, France. julie.legal@aphp.fr.
Marie DesmarestPaediatric Migraine & Neurovascular diseases Unit, Department of Paediatrics, Robert Debré Hospital, Paris Diderot University, Sorbonne Paris Cité, Paris, France. mariedesmarest@hotmail.fr.
Claudio VeropalumboDepartment of Translational Medicine-Section of Pediatrics, Federico II University, Naples, Italy. claveropalu@hotmail.it.
Silvia RomanelloPaediatric Emergency Department, Robert Debré Hospital, Paris Diderot University, Sorbonne Paris Cité, Paris, France. silviaromanello@yahoo.it.
Luigi TitomanlioPaediatric Migraine & Neurovascular diseases Unit, Department of Paediatrics, Robert Debré Hospital, Paris Diderot University, Sorbonne Paris Cité, Paris, France. luigi.titomanlio@rdb.aphp.fr.
Délégation Paris 7 · FRFederico II University Hospital · ITSorbonne Paris Cité · FRUniversity for Foreigners Perugia · ITUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stroke is a rare disease in childhood with an estimated incidence of 1-6/100.000. It has an increasingly recognised impact on child mortality along with its outcomes and effects on quality of life of patients and their families. Clinical presentation and risk factors of paediatric stroke are different to those of adults therefore it can be considered as an independent nosological entity. The relative rarity, the age-related peculiarities and the variety of manifested symptoms makes the diagnosis of paediatric stroke extremely difficult and often delayed. History and clinical examination should investigate underlying diseases or predisposing factors and should take into account the potential territoriality of neurological deficits and the spectrum of differential diagnosis of acute neurological accidents in childhood. Neuroimaging (in particular diffusion weighted magnetic resonance) is the keystone for diagnosis of paediatric stroke and other investigations might be considered according to the clinical condition. Despite substantial advances in paediatric stroke research and clinical care, many unanswered questions remain concerning both its acute treatment and its secondary prevention and rehabilitation so that treatment recommendations are mainly extrapolated from studies on adult population. We have tried to summarize the pathophysiological and clinical characteristics of arterial ischemic stroke in children and the most recent international guidelines and practical directions on how to recognise and manage it in paediatric emergency.

Indexed as

Brain IschemiaDisease ManagementQuality of LifeAcute DiseaseChildGlobal HealthHumansIncidenceNeuroimagingSurvival Rate

Identifiers

PMID26631262
PMCPMC4668709
OpenAlexW2182552203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.