ArticleBMJ open2015
Risk factors for hospital admission in the 28 days following a community-acquired pneumonia diagnosis in older adults, and their contribution to increasing hospitalisation rates over time: a cohort study.
Article in BMJ open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Pooled it
- Effects of fluid and drinking on pneumonia mortality in older adults: A systematic review and meta-analysis.Clinical nutrition ESPEN · 2022Pooled it
- Trial
- Thirty-day hospital readmission and its determinants among patients with severe community-acquired pneumonia: a prospective cross-sectional study in Northwest Ethiopia.BMC infectious diseases · 2026Article
- Biological sex influences severity and outcomes inMicrobiology spectrum · 2025Article
- Accuracy of the recording of pneumonia events in English electronic healthcare record data in patients with chronic obstructive pulmonary disease.Pneumonia (Nathan Qld.) · 2024Article
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- Primary Care Antibiotic Prescribing and Infection-Related Hospitalisation.Antibiotics (Basel, Switzerland) · 2023Review
- Metformin Use Is Associated With Lower Mortality in Veterans With Diabetes Hospitalized With Pneumonia.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- Long-Term Effects of Hospitalization for COVID-19 on Frailty and Quality of Life in Older Adults ≥80 Years.Journal of clinical medicine · 2022Article
- Infection Control Measures and Prevalence of SARS-CoV-2 IgG among 4,554 University Hospital Employees, Munich, Germany.Emerging infectious diseases · 2022Article
- COVID-19-Associated Mortality in US Veterans with and without SARS-CoV-2 Infection.International journal of environmental research and public health · 2021Article
- Frailty Is Associated With Neutrophil Dysfunction Which Is Correctable With Phosphoinositol-3-Kinase Inhibitors.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
- Observational
- Clinical and financial burden of hospitalised community-acquired pneumonia in patients with selected underlying comorbidities in England.BMJ open respiratory research · 2020Article
- Community-acquired pneumonia in critically ill very old patients: a growing problem.European respiratory review : an official journal of the European Respiratory Society · 2020Review
- Editorial: Nicotine and SARS-CoV-2: COVID-19 may be a disease of the nicotinic cholinergic system.Toxicology reports · 2020Article
- Impact of introducing electronic acute kidney injury alerts in primary care.Clinical kidney journal · 2019Article
- Impact of Low Cardiovascular Risk Profiles on Geriatric Outcomes: Evidence From 421,000 Participants in Two Cohorts.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019Article
- Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectivesTo determine factors associated with hospitalisation after community-acquired pneumonia (CAP) among older adults in England, and to investigate how these factors have contributed to increasing hospitalisations over time.
designCohort study.
settingPrimary and secondary care in England. POPULATION: 39,211 individuals from the Clinical Practice Research Datalink, who were eligible for linkage to Hospital Episode Statistics and mortality data, were aged ≥ 65 and had at least 1 CAP episode between April 1998 and March 2011.
main outcome measuresThe association between hospitalisation within 28 days of CAP diagnosis (a 'post-CAP' hospitalisation) and a wide range of comorbidities, frailty factors, medications and vaccinations. We examined the role of these factors in post-CAP hospitalisation trends. We also looked at trends in post-CAP mortality and length of hospitalisation over the study period.
results14 comorbidities, 5 frailty factors and 4 medications/vaccinations were associated with hospitalisation (of 18, 12 and 7 considered, respectively). Factors such as chronic lung disease, severe renal disease and diabetes were associated with increased likelihood of hospitalisation, whereas factors such as recent influenza vaccination and a recent antibiotic prescription decreased the odds of hospitalisation. Despite adjusting for these and other factors, the average predicted probability of hospitalisation after CAP rose markedly from 57% (1998-2000) to 86% (2009-2010). Duration of hospitalisation and 28-day mortality decreased over the study period.
conclusionsThe risk factors we describe enable identification of patients at increased likelihood of post-CAP hospitalisation and thus in need of proactive case management. Our analyses also provide evidence that while comorbidities and frailty factors contributed to increasing post-CAP hospitalisations in recent years, the trend appears to be largely driven by changes in service provision and patient behaviour.
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