ArticleEuropean radiology2016
Optimal boundary detection method and window settings for coronary atherosclerotic plaque volume analysis in coronary computed tomography angiography: comparison with intravascular ultrasound.
Article in European radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Coronary CT Angiography-Based Prediction Model for Hemodynamically Significant Coronary Stenosis Integrating Morphological and Plaque Characteristics.Cardiovascular engineering and technology · 2026Article
- QUIET WARRIOR - Rationale and design: An ancillary study to the Women's IschemiA TRial to Reduce Events in Nonobstructive CAD (WARRIOR).American heart journal plus : cardiology research and practice · 2025Article
- Coronary CT Angiography-based Morphologic Index for Predicting Hemodynamically Significant Coronary Stenosis.Radiology. Cardiothoracic imaging · 2023Observational
- Characteristic findings of microvascular dysfunction on coronary computed tomography angiography in patients with intermediate coronary stenosis.European radiology · 2021Article
- Prognostic Implications of Comprehensive Whole Vessel Plaque Quantification Using Coronary Computed Tomography Angiography.JACC. Asia · 2021Article
- Diagnostic Performance of Fractional Flow Reserve From CT Coronary Angiography With Analytical Method.Frontiers in cardiovascular medicine · 2021Article
- Influence of tube potential on quantitative coronary plaque analyses by low radiation dose computed tomography: a phantom study.The international journal of cardiovascular imaging · 2018Article
- Discrepancies between coronary CT angiography and invasive coronary angiography with focus on culprit lesions which cause future cardiac events.European radiology · 2018Article
- Evaluation of Atherosclerotic Plaque in Non-invasive Coronary Imaging.Korean circulation journal · 2018Review
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7 authors.
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Abstract
objectiveTo evaluate optimal methodology for quantitative plaque volume analysis by coronary CT angiography (QCT).
methodsFifty-one coronary artery segments were evaluated and contour measurements based on two different methods [(1) no gap, or (2) fixed 0.3-mm gap between inner and outer boundary] were compared with intravascular ultrasound (IVUS). In addition, three different window width (WW) and level (WL) settings [fixed (740/220) Hounsfield unit (HU), adjusted (155 % and 65 % of mean luminal intensity of the segment, and aorta adjusted (155 % and 65 % of mean luminal intensity of central aorta)] were used for semiautomated plaque volume analysis.
resultsFor boundary detection, the no gap method led to underestimation compared with IVUS (105.4 ± 82.3 vs. 136.1 ± 72.8 mm(3), p < 0.001), while fixed 0.3-mm gap showed no difference between IVUS and QCT (136.1 ± 72.8 vs. 139.8 ± 93.9 mm(3), p = 0.50). Comparison of the three different window settings demonstrated that the aorta adjusted setting underestimated (120.5 ± 74.3 vs. 136.1 ± 72.8 mm(3), p = 0.003), while fixed setting showed the least mean difference compared with IVUS (3.8 ± 39.8 mm(3), p = 0.50).
conclusionFor plaque volumetric assessment, optimal results were obtained with fixed 0.3-mm gap with fixed HU setting (740/220). KEY POINTS: • Quantitative plaque volume analysis by coronary CT angiography has recently emerged. • Different boundary detection methods and window width and level settings were evaluated. • Fixed 0.3-mm gap with fixed HU setting (740/220) afforded optimal results.
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