Evidence map›Paper›PMID 26630933›Full record

ArticleBMC pulmonary medicine2015

Incidental gastrointestinal 18F-Fluorodeoxyglucose uptake associated with lung cancer.

Juliette Vella-Boucaud, Dimitri Papathanassiou, Olivier Bouche, Alain Prevost, Thibault Lestra, Sandra Dury, Hervé Vallerand, Jeanne-Marie Perotin, Claire Launois, Louis Boissiere and 3 more

Open access · goldAbstract read
In one paragraph

Article in BMC pulmonary medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Juliette Vella-BoucaudService des Maladies Respiratoires, Hôpital Maison Blanche, CHU de Reims, 45 rue Cognacq Jay, 51092, Reims, Cedex, France. jvellaboucaud@chu-reims.fr.
Dimitri PapathanassiouService de Médecine Nucléaire, Institut Jean Godinot, Centre de Lutte Contre le Cancer à Reims, Reims, France. D.PAPATHANASSIOU@reims.unicancer.fr.
Olivier BoucheService d'Hépato-Gastro-Entérologie et Cancérologie Digestive, Hôpital Robert Debré, CHU de Reims, Reims, France. obouche@chu-reims.fr.
Alain PrevostService d'Oncologie Médicale, Institut Jean Godinot, Centre de Lutte Contre le Cancer à Reims, Reims, France. alain.prevost@reims.fnclcc.fr.
Thibault LestraService de Médecine Nucléaire, Institut Jean Godinot, Centre de Lutte Contre le Cancer à Reims, Reims, France. tlestra@chu-reims.fr.
Sandra DuryService des Maladies Respiratoires, Hôpital Maison Blanche, CHU de Reims, 45 rue Cognacq Jay, 51092, Reims, Cedex, France. sdury@chu-reims.fr.
Hervé VallerandService des Maladies Respiratoires, Hôpital Maison Blanche, CHU de Reims, 45 rue Cognacq Jay, 51092, Reims, Cedex, France. hvallerand@chu-reims.fr.
Jeanne-Marie PerotinService des Maladies Respiratoires, Hôpital Maison Blanche, CHU de Reims, 45 rue Cognacq Jay, 51092, Reims, Cedex, France. jmperotin-collard@chu-reims.fr.
Claire LaunoisService des Maladies Respiratoires, Hôpital Maison Blanche, CHU de Reims, 45 rue Cognacq Jay, 51092, Reims, Cedex, France. claunois@chu-reims.fr.
Louis BoissiereService des Maladies Respiratoires, Hôpital Maison Blanche, CHU de Reims, 45 rue Cognacq Jay, 51092, Reims, Cedex, France. lboissiere@chu-reims.fr.
Mathilde BrasseurService d'Hépato-Gastro-Entérologie et Cancérologie Digestive, Hôpital Robert Debré, CHU de Reims, Reims, France. mbrasseur@chu-reims.fr.
François LebargyService des Maladies Respiratoires, Hôpital Maison Blanche, CHU de Reims, 45 rue Cognacq Jay, 51092, Reims, Cedex, France. flebargy@chu-reims.fr.
Gaëtan DesleeService des Maladies Respiratoires, Hôpital Maison Blanche, CHU de Reims, 45 rue Cognacq Jay, 51092, Reims, Cedex, France. gdeslee@chu-reims.fr.
Hôpital Maison Blanche · FRCentre Hospitalier Universitaire de Reims · FRInstitut Jean Godinot · FRUniversité de Reims Champagne-Ardenne · FRHôpital Robert-Debré · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundF-Fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) is increasingly used for the initial staging and restaging of lung cancer. Incidental gastrointestinal findings are often observed on (18)F-FDG PET/CT. The objective of this study was to assess incidental 18F-FDG uptake by the gastrointestinal tract (GIT) in patients with lung cancer.

methodsTwo hundred thirty consecutive 18F-FDG PET/CT examinations performed for lung cancer over a 3-year period were retrospectively reviewed for the presence of incidental FDG uptake in the GIT. The charts of patients with positive FDG uptake were then reviewed and analysed to determine the GIT uptake sites, the standardized uptake value (SUV) max and the final clinical diagnosis.

resultsFifty-two patients (52/230, 23%) demonstrated incidental FDG uptake in the GIT. Thirty-three patients (63.5%) had diffuse uptake (oesophagus, n = 2, colon, n = 31) and 19 patients (36.5%) had focal uptake (oesophagus, n = 1, small bowel, n = 1, ascending colon, n = 5, descending colon, n = 4, sigmoid, n = 4, rectum, n = 3, and anal margin, n = 1). Twelve of the 52 patients with GIT uptake were further investigated, revealing, a diagnosis of malignancy in 4 patients with focal FDG uptake. No significant differences in mean SUVmax were observed between patients with malignant and benign GIT diseases.

conclusionThis study demonstrates a high incidence of FDG uptake in the GIT associated with lung cancer. Focal GIT uptake was frequently associated with malignant disease. These results suggest that further GIT investigations should be performed in patients with focal GIT uptake.

Indexed as

Positron-Emission TomographyTomography, X-Ray ComputedAgedFemaleFluorodeoxyglucose F18Gastrointestinal TractHumansIncidental FindingsLung NeoplasmsMaleMiddle AgedRadiopharmaceuticalsRetrospective StudiesFluorodeoxyglucose F18Radiopharmaceuticals

Identifiers

PMID26630933
PMCPMC4668630
OpenAlexW2182427097

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.