Evidence map›Paper›PMID 26630205›Full record

ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2016

Construct damage and loosening around glenoid implants: A longitudinal micro-CT study of five cadaver specimens.

Gregory S Lewis, Jacob B Brenza, Emmanuel M Paul, April D Armstrong

Abstract read
In one paragraph

Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Peri-implant stress correlates with bone and cement morphology: Micro-FE modeling of implanted cadaveric glenoids.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gregory S LewisDepartment of Orthopaedics and Rehabilitation, Penn State College of Medicine and M.S. Hershey Medical Center, 500 University Drive, Mail Code H089, Hershey, Pennsylvania, 17033.
Jacob B BrenzaDepartment of Orthopaedics and Rehabilitation, Penn State College of Medicine and M.S. Hershey Medical Center, 500 University Drive, Mail Code H089, Hershey, Pennsylvania, 17033.
Emmanuel M PaulDepartment of Orthopaedics and Rehabilitation, Penn State College of Medicine and M.S. Hershey Medical Center, 500 University Drive, Mail Code H089, Hershey, Pennsylvania, 17033.
April D ArmstrongDepartment of Orthopaedics and Rehabilitation, Penn State College of Medicine and M.S. Hershey Medical Center, 500 University Drive, Mail Code H089, Hershey, Pennsylvania, 17033.

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
Penn State Clinical and Translational Science InstituteUL1TR000127 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$17.1M
Penn State Clinical and Translational Science InstituteKL2TR000126 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$3.2M
NCATS NIH HHS KL2 TR000126NCATS NIH HHS UL1 TR000127NCATS NIH HHS UL1 TR002014
6 · The paper itself

Abstract

The evolution of failure of bone and cement leading to loosening of glenoid components following shoulder arthroplasty is not well understood. The purpose of this study was to identify and visualize potential mechanisms of mechanical failure within cadavers, cemented with two types of components, and subject to cyclic loading. Five glenoid cadaver bones were implanted with either a three-pegged polyethylene component, or prototype posteriorly augmented component which addresses posterior bone loss. Specimens were loaded by constant glenohumeral compression combined with cyclic anterior-posterior displacement of the humeral head relative to the glenoid. At six time points across 100,000 cycles, implant loosening micromotions were optically measured, and specimens were imaged by micro-computed tomography. Scans were 3D registered and inspected for crack initiation and progression, and micro-CT based time-lapse movies were created. Cement cracking initiated at stress concentrations and progressed with additional cyclic loading. Failure planes within trabecular bone and the bone-cement interface were identified in four of the five specimens. Implant subsidence increased to greater than 1.0 mm in two specimens. Cemented glenoid structural failure can occur within the cement, along planes of trabecular bone, or at the bone cement interface. © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 34:1053-1060, 2016.

Indexed as

Prosthesis FailureShoulder ProsthesisHumansLongitudinal StudiesShoulder JointX-Ray Microtomographyglenoid componentimplant fixationimplant looseningmicro-computed tomographytotal shoulder arthroplasty

Identifiers

PMID26630205
PMCPMC5800522

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.