ArticleDepression and anxiety2016
DISTINCT ETIOLOGICAL INFLUENCES ON OBSESSIVE-COMPULSIVE SYMPTOM DIMENSIONS: A MULTIVARIATE TWIN STUDY.
Article in Depression and anxiety, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03128749 (Mindfulness-Based Cognitive Therapy), which is not on this map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Mindfulness-Based Cognitive Therapy: Efficacy and fMRI-based Response Predictors in a Group of OCD Patients Non-responders to CBT
Who cites it
7 citing papers in PubMed.
- No Biased Attention to Threat, Incompleteness, and Disgust in Youth with OCD and Anxiety Disorders.Research on child and adolescent psychopathology · 2025Article
- Symptom Dimension Breakpoints for the Obsessive-Compulsive Inventory-Child Version (OCI-CV).Child psychiatry and human development · 2023Article
- Measuring symptoms of obsessive-compulsive and related disorders using a single dimensional self-report scale.Frontiers in psychiatry · 2023Article
- Involvement of fear, incompleteness, and disgust during symptoms of pediatric obsessive-compulsive disorder.European child & adolescent psychiatry · 2021Article
- The Centrality of Doubting and Checking in the Network Structure of Obsessive-Compulsive Symptom Dimensions in Youth.Journal of the American Academy of Child and Adolescent Psychiatry · 2020Article
- Life in a post-pandemic world: What to expect of anxiety-related conditions and their treatment.Journal of anxiety disorders · 2020Article
- Genetic and phenotypic overlap of specific obsessive-compulsive and attention-deficit/hyperactive subtypes with Tourette syndrome.Psychological medicine · 2018Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundObsessive-compulsive disorder (OCD) is characterized by five major dimensions, including contamination/washing, harm/checking, symmetry/ordering, hoarding, and forbidden thoughts. How these dimensions may relate etiologically to the symptoms of other obsessive-compulsive related disorders (OCRDs) and anxiety disorders (ADs) is not well known. The aim of this study was to examine the genetic and environmental overlap between each major obsessive-compulsive dimension with the symptoms of other OCRDs and ADs.
methodsTwo thousand four hundred ninety-five twins of both sexes, aged between 18 and 45 years, were recruited from the Australian Twin Registry. Measures used scores on four dimensions (obsessing (forbidden thoughts), washing, checking, and ordering) of the Obsessive-Compulsive Inventory-Revised, Dysmorphic Concerns Questionnaire, Hoarding Rating Scale, Anxiety Sensitivity Index, Social Phobia Inventory, and Stress subscale of the Depression, Anxiety, and Stress Scale. Multivariate twin modeling methods using continuous and categorized variables were performed, also controlling for age and gender.
resultsOur findings suggested that forbidden thoughts and washing demonstrated the strongest genetic overlap with other AD symptoms, while ordering was genetically related to OCRD symptoms. Common genetic influences on checking symptoms were best estimated when modeling OCRDs together with AD symptoms. Common environmental factors of ordering and checking were shared with AD symptoms.
conclusionsImportant shared genetic and environmental risk factors exist between OCD, OCRDs, and ADs, but which vary alongside the expression of its major dimensions.
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