Evidence map›Paper›PMID 26629705›Full record

ArticlePloS one2015

The Cytochrome bd Oxidase of Porphyromonas gingivalis Contributes to Oxidative Stress Resistance and Dioxygen Tolerance.

Julia Leclerc, Eric Rosenfeld, Mathieu Trainini, Bénédicte Martin, Vincent Meuric, Martine Bonnaure-Mallet, Christine Baysse

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Gut microbes · 2026
    Article
  3. Article
  4. The polymicrobial pathogenicity ofFrontiers in oral health · 2024
    Article
  5. Article
  6. Article
  7. Bacterial Oxidases of the CytochromeAntioxidants & redox signaling · 2021
    Review
  8. ROS Defense Systems and Terminal Oxidases in Bacteria.Antioxidants (Basel, Switzerland) · 2021
    Review
  9. Article
  10. Article
  11. Article
  12. The CytochromeFrontiers in microbiology · 2018
    Article
  13. Expression patterns ofInfection and drug resistance · 2018
    Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Julia LeclercEA1254 Microbiologie-Risques Infectieux, University of Rennes1, Rennes, France.
Eric RosenfeldUMR CNRS 7266 LIENSs, University of La Rochelle, La Rochelle, France.
Mathieu TraininiEA1254 Microbiologie-Risques Infectieux, University of Rennes1, Rennes, France.
Bénédicte MartinEA1254 Microbiologie-Risques Infectieux, University of Rennes1, Rennes, France.
Vincent MeuricEA1254 Microbiologie-Risques Infectieux, University of Rennes1, CHU Rennes, Rennes, France.
Martine Bonnaure-MalletEA1254 Microbiologie-Risques Infectieux, University of Rennes1, CHU Rennes, Rennes, France.
Christine BaysseEA1254 Microbiologie-Risques Infectieux, University of Rennes1, Rennes, France.
Université de Rennes · FRLa Rochelle Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porphyromonas gingivalis is an etiologic agent of periodontal disease in humans. The disease is associated with the formation of a mixed oral biofilm which is exposed to oxygen and environmental stress, such as oxidative stress. To investigate possible roles for cytochrome bd oxidase in the growth and persistence of this anaerobic bacterium inside the oral biofilm, mutant strains deficient in cytochrome bd oxidase activity were characterized. This study demonstrated that the cytochrome bd oxidase of Porphyromonas gingivalis, encoded by cydAB, was able to catalyse O2 consumption and was involved in peroxide and superoxide resistance, and dioxygen tolerance.

Indexed as

Oxidative StressBacterial AdhesionCell LineElectron Transport Complex IVMutationOxygenPeroxidesPorphyromonas gingivalisRNA, MessengerSuperoxidesTranscription, GeneticElectron Transport Complex IVOxygenPeroxidesRNA, MessengerSuperoxides

Identifiers

PMID26629705
PMCPMC4668044
OpenAlexW2194491805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.