ArticleInternational journal of molecular and cellular medicine2015
Diversity of Variable Number Tandem Repeat Loci in Shigella Species Isolated from Pediatric Patients.
Article in International journal of molecular and cellular medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed, 21 citations in OpenAlex.
- Molecular characterization and antimicrobial resistance profiles of Shigella flexneri isolates from pediatric clinical cases in Ahvaz, Iran.Scientific reports · 2026Article
- Virulence factors and molecular characteristics of Shigella flexneri isolated from calves with diarrhea.BMC microbiology · 2021Article
- Multilocus Variable-Number Tandem-Repeat Analysis for Geno-typing ofIranian journal of public health · 2020Article
- Bacterial CRISPR Regions: General Features and their Potential for Epidemiological Molecular Typing Studies.The open microbiology journal · 2018Review
- Antibiotic resistance, virulence factors and genotyping of UropathogenicAntimicrobial resistance and infection control · 2018Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multilocus variable number tandem repeat (VNTR) analysis (MLVA) is a new typing method with several advantages compared to other methods. Dissemination of Shigella is highly significant in developing countries. Whilst Shigella is becoming increasingly important as an etiologic agent of pediatric shigellosis in Iran, little is known about the genetic diversity of the local strains. Therefore, the aim of this study was to describe the genetic diversity of Shigella species isolated from pediatric patients in Tehran, Iran. A total of 53 Shigella isolates were obtained from 1070 patients with diarrhea (less than 12 years of age). All isolates were identified by routine biochemical and serological tests. The confirmed Shigella isolates were further serogrouped (by the slide agglutination) using slide agglutination method. MLVA assay with the seven loci resolved 53 Shigella isolates into 36 different genotypes. Almost all the isolates were classified into five clonal complexes. Furthermore, our MLVA assay could effectively distinguish the four Shigella species. This study has provided valuable insights into the genetic heterogeneity of Shigella species in Tehran, Iran. Our findings can be helpful for further epidemiological surveillance of Shigella species in this country in the future.
Indexed as
Identifiers
26629486PMC4644529W1931705369What OpenQuestion holds
Registered trials
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