ArticleAvicenna journal of medicine
Acute promyelocytic leukemia presenting as pulmonary thromboembolism: Not all APLs bleed.
Article in Avicenna journal of medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 4 citations in OpenAlex.
- Acute promyelocytic leukemia presenting as recurrent venous and arterial thrombotic events: a case report and review of the literature.Journal of community hospital internal medicine perspectives · 2021Article
- Massive Pulmonary Embolism at the Onset of Acute Promyelocytic Leukemia.Mediterranean journal of hematology and infectious diseases · 2016Article
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Authors and funding
4 authors at 2 institutions in 1 country.
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Abstract
We present a rare case of acute promyelocytic leukemia (APL) presenting as pulmonary thromboembolism being misdiagnosed as community-acquired pneumonia. Thrombotic phenomenon in APL are poorly understood and grossly underreported. In our case, following no response to standard antibiotic treatment, the patient was further investigated and detected to have an acute pulmonary thromboembolism following right lower limb deep vein thrombosis (DVT). Though, complete blood picture revealed only mild hyperleukocytosis, bone marrow biopsy and aspiration revealed 60% blasts and a positive t (15,17)(q22,12) and PML retinoic acid receptor alpha (RARA) fusion protein on molecular cytogenetics. He was diagnosed as APL and received treatment with all-transretinoic acid (ATRA) and arsenic trioxide (ATO) and therapeutic anticoagulation.
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