ArticleF1000Research2015
Embryo-lethal phenotypes in early abp1 mutants are due to disruption of the neighboring BSM gene.
Article in F1000Research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 41 citations in OpenAlex.
- Dressed Up to the Nines: The Interplay of Phytohormones Signaling and Redox Metabolism During Plant Response to Drought.Plants (Basel, Switzerland) · 2025Review
- Save your TIRs - more to auxin than meets the eye.The New phytologist · 2023Review
- Article
- Fourteen Stations of Auxin.Cold Spring Harbor perspectives in biology · 2022Review
- The Story of Auxin-Binding Protein 1 (ABP1).Cold Spring Harbor perspectives in biology · 2021Review
- Function of membrane domains in rho-of-plant signaling.Plant physiology · 2021Review
- Auxin does not inhibit endocytosis of PIN1 and PIN2 auxin efflux carriers.Plant physiology · 2021Article
- The plant AlcR-pAlcA ethanol-inducible system displays gross growth artefacts independently of downstream pAlcA-regulated inducible constructs.Scientific reports · 2021Article
- Non-canonical auxin signalling: fast and curious.Journal of experimental botany · 2019Article
- Auxin Signaling.Plant physiology · 2018Review
- Control of organelle gene expression by the mitochondrial transcription termination factor mTERF22 in Arabidopsis thaliana plants.PloS one · 2018Article
- Protoplast Swelling and Hypocotyl Growth Depend on Different Auxin Signaling Pathways.Plant physiology · 2017Article
- Primitive Auxin Response without TIR1 and Aux/IAA in the Charophyte AlgaPlant physiology · 2017Article
- Auxin perception and downstream events.Current opinion in plant biology · 2016Review
- Vascular cambium regeneration and vessel formation in wounded inflorescence stems of Arabidopsis.Scientific reports · 2016Article
- Article
- Brachypodium distachyon T-DNA insertion lines: a model pathosystem to study nonhost resistance to wheat stripe rust.Scientific reports · 2016Article
- Up in the air: Untethered Factors of Auxin Response.F1000Research · 2016Review
- Transcription of TIR1-Controlled Genes Can be Regulated within 10 Min by an Auxin-Induced Process. Can TIR1 be the Receptor?Frontiers in plant science · 2016Article
- Strong morphological defects in conditional Arabidopsis abp1 knock-down mutants generated in absence of functional ABP1 protein.F1000Research · 2016Article
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Auxin Binding Protein1 (ABP1) has been identified based on its ability to bind auxin with high affinity and studied for a long time as a prime candidate for the extracellular auxin receptor responsible for mediating in particular the fast non-transcriptional auxin responses. However, the contradiction between the embryo-lethal phenotypes of the originally described Arabidopsis T-DNA insertional knock-out alleles ( abp1-1 and abp1-1s) and the wild type-like phenotypes of other recently described loss-of-function alleles ( abp1-c1 and abp1-TD1) questions the biological importance of ABP1 and relevance of the previous genetic studies. Here we show that there is no hidden copy of the ABP1 gene in the Arabidopsis genome but the embryo-lethal phenotypes of abp1-1 and abp1-1s alleles are very similar to the knock-out phenotypes of the neighboring gene, BELAYA SMERT ( BSM). Furthermore, the allelic complementation test between bsm and abp1 alleles shows that the embryo-lethality in the abp1-1 and abp1-1s alleles is caused by the off-target disruption of the BSM locus by the T-DNA insertions. This clarifies the controversy of different phenotypes among published abp1 knock-out alleles and asks for reflections on the developmental role of ABP1.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.