ArticleInternational journal of clinical and experimental medicine2015
Intravertebral clefts in osteoporotic compression fractures of the spine: incidence, characteristics, and therapeutic efficacy.
Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 31 citations in OpenAlex.
- Percutaneous kyphoplasty assisted with/without mixed reality technology in treatment of OVCF with IVC: a prospective study.Journal of orthopaedic surgery and research · 2019Trial
- Biomechanical study of robot-navigated targeted cross-puncture percutaneous vertebroplasty for Kümmell's disease: finite element analysis.Frontiers in rehabilitation sciences · 2026Article
- Double Vertebrae Kümmell Disease: Five Cases Report and Literature Review.Orthopaedic surgery · 2023Review
- Diagnosis and Treatment of Skipped Multifocal Spinal Tuberculosis Lesions.Orthopaedic surgery · 2023Review
- Bone microarchitecture and metabolism in elderly male patients with signs of intravertebral cleft on MRI.European radiology · 2022Article
- Percutaneous Kyphoplasty in Patients with Severe Osteoporotic Vertebral Compression Fracture with and without Intravertebral Cleft: A Retrospective Comparative Study.International journal of general medicine · 2022Article
- Comparative Efficacy of Three Minimally Invasive Procedures for Kümmell's Disease: A Systematic Review and Network Meta-Analysis.Frontiers in surgery · 2022Review
- What are risk factors for subsequent fracture after vertebral augmentation in patients with thoracolumbar osteoporotic vertebral fractures.BMC musculoskeletal disorders · 2021Article
- Unilateral Posterior Surgery for Severe Osteoporotic Vertebrae Fractures' Sequelae in Geriatric Population: Minimum 5-Year Results of 109 Patients.Neurospine · 2021Article
- Predictive risk factors for recollapse of cemented vertebrae after percutaneous vertebroplasty: A meta-analysis.World journal of clinical cases · 2021Article
- Analysis of the effect of percutaneous vertebroplasty in the treatment of thoracolumbar Kümmell's disease with or without bone cement leakage.BMC musculoskeletal disorders · 2021Article
- Intravertebral cleft in pathological vertebral fracture resulting from spinal tuberculosis: a case report and literature review.BMC musculoskeletal disorders · 2020Review
- Clinical observation of two bone cement distribution modes of percutaneous vertebroplasty in the treatment of thoracolumbar Kümmell's disease.Journal of orthopaedic surgery and research · 2020Article
- The therapeutic effects of percutaneous kyphoplasty on osteoporotic vertebral compression fractures with or without intravertebral cleft.International orthopaedics · 2019Article
- Posterior Fixation Combined with Vertebroplasty or Vertebral Column Resection for the Treatment of Osteoporotic Vertebral Compression Fractures with Intravertebral Cleft Complicated by Neurological Deficits.BioMed research international · 2019Article
- What are the predictors of clinical success after percutaneous vertebroplasty for osteoporotic vertebral fractures?European radiology · 2018Article
- What is the Current Evidence on Vertebral Body Osteonecrosis?: A Systematic Review of the Literature.Asian spine journal · 2018Review
- Refracture of osteoporotic vertebral body after treatment by balloon kyphoplasty: Three cases report.Medicine · 2017Review
- Observational
- Intravertebral cleft in pathological vertebral collapse resulting from cancer metastasis: report of three cases.Skeletal radiology · 2016Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the pathogenesis and characteristics and to assess the long-term effectiveness of polymethylmethacry late (PMMA) vertebroplasty treatment in patients with intravertebral cleft (IVC) in osteoporotic compression fractures.
methodsA retrospective analysis of radiological and clinical parameters was performed on 388 patients who underwent percutaneous vertebroplasty or kyphoplasty to treat osteoporotic compression fractures from January 2010 to October 2012. IVC sign was observed in the MRI of 47 patients. Postoperative follow-ups were conducted for at least 2 years after surgery.
resultsIVC incidence was associated with older age and lower bone mineral density. Other baseline measurements, such as preoperative visual analogue scale and Oswestry Disability Index (ODI), showed no significant difference between IVC and non-IVC fracture patients. Vertebral height and kyphotic angle were corrected after percutaneous vertebroplasty or kyphoplasty with no significant difference in outcome between the two procedures. Restored vertebral height collapsed and the kyphotic angle became aggravated during the 2 years following surgery in patients with IVC. Similarly, initial improvements in visual analogue scale and ODI decreased over time. Non-IVC patients' had a slight recurrence of compression and kyphosis that began to normalize after 1 year. Visual analogue scale and ODI at 2 years' post-surgery was also significantly lower in non-IVC than IVC patients.
conclusionPolymethylmethacrylate vertebroplasty treatment of osteoporotic compression fractures is initially effective for patients with signs of IVC, but compression and kyphosis gradually reoccur. Therefore, we strongly recommend strict observation and follow-up after vertebroplasty.
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26629251PMC4659139W2184050514What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.