Evidence map›Paper›PMID 26629210›Full record

ArticleInternational journal of clinical and experimental medicine2015

Relationship between adiponectin receptor 1 gene polymorphisms and ischemic stroke.

Qian Han, Zunhua Shu, Xuemei Liang, Rui Mi, Lei Yang, Peng Li

Abstract read
PubMed Full text at PMC
In one paragraph

Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Qian HanDepartment of Internal Neurology, Tianjin 4th Central Hospital Tianjin 300140, China.
Zunhua ShuDepartment of Medical Affairs, Affiliated Hospital of Changchun University of Traditional Chinese Medicine Changchun 130021, China.
Xuemei LiangDepartment of Internal Neurology, Tianjin 4th Central Hospital Tianjin 300140, China.
Rui MiCollege of Humanities, Kunming Medical University China.
Lei YangDepartment of Neurosurgery , Kunming Children's Hospital Kunming 650030, China.
Peng LiMedical Faculty of Kunming University of Science and Technology Kunming 650000, China.
Tianjin Central Hospital of Gynecology Obstetrics · CNChangchun University of Chinese Medicine · CNKunming Children's Hospital · CNKunming Medical University · CNKunming University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePrevious study suggested adiponectin receptor 2 (ADIPOR2) genetic polymorphisms were associated with the risk of ischemic stroke. However, the relation between adiponectin receptor 1 (ADIPOR1) gene polymorphism and stroke remains unclear.

methodsIn the present study, we utilized the polymerase chain reaction-sequencing method to detect rs2275737 and s1342387 genotypes of ADIPOR1 gene in 300 cases of ischemic stroke patients and 300 age- and sex- matched healthy controls.

resultsFor rs2275737, we found A allele carriers have increased risk to ischemic stroke (OR=2.570, 95% CI: 1.999-3.305); also, we found rs1342387 A allele was associated with the risk for stroke (OR=1.351, 95% CI: 1.074-1.699). After adjusted for confounders such as hypertension, diabetes, and smoking, we found the association remains significant.

conclusionADIPOR1 genetic polymorphism may increase the risk of ischemic stroke.

Indexed as

adiponectin receptor 1 geneIschemic strokesingle nucleotide polymorphisms

Identifiers

PMID26629210
PMCPMC4659098
OpenAlexW2216939304

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.