Evidence map›Paper›PMID 26629173›Full record

ArticleInternational journal of clinical and experimental medicine2015

Correlation between body mass index and clinicopathological features of papillary thyroid microcarcinoma.

Zeming Liu, Yusufu Maimaiti, Pan Yu, Yiquan Xiong, Wen Zeng, Xiaoyu Li, Haiping Song, Chong Lu, Yue Xin, Jing Zhou and 8 more

Abstract read

PubMed Full text at PMC

In one paragraph

Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it

0cells of the map it votes in

10citing papers in PubMed, 3 pooled it

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it.

Association of BMI with Clinicopathological Features of Papillary Thyroid Cancer: A Systematic Review and Meta-Analysis.World journal of surgery · 2021
Pooled it
Association Between Aggressive Clinicopathologic Features of Papillary Thyroid Carcinoma and Body Mass Index: A Systematic Review and Meta-Analysis.Frontiers in endocrinology · 2021
Pooled it
Associations between BRAF(V600E) and prognostic factors and poor outcomes in papillary thyroid carcinoma: a meta-analysis.World journal of surgical oncology · 2016
Pooled it
Uncovering the pathogenesis of obesity complicated with papillary thyroid carcinoma via bioinformatics and experimental validation.Aging · 2023
Article
Potential Impact of Body Mass Index on the Clinical Outcome of Papillary Thyroid Cancer After High-Dose Radioactive Iodine Therapy.Frontiers in endocrinology · 2022
Article
Combinatorial Therapies in Thyroid Cancer: An Overview of Preclinical and Clinical Progresses.Cells · 2020
Review
Lack of association between obesity and aggressiveness of differentiated thyroid cancer.Journal of endocrinological investigation · 2019
Article
The impact of BMI on clinical progress, response to treatment, and disease course in patients with differentiated thyroid cancer.PloS one · 2018
Article
Associations between body mass index and lymph node metastases of patients with papillary thyroid cancer: A retrospective study.Medicine · 2017
Observational
Pretreatment BMI Is Associated with Aggressive Clinicopathological Features of Papillary Thyroid Carcinoma: A Multicenter Study.International journal of endocrinology · 2017
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Zeming LiuDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China.

Yusufu MaimaitiDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China.

Pan YuDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China.

Yiquan XiongDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China.

Wen ZengDepartment of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, Hubei, China.

Xiaoyu LiDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China.

Haiping SongDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China.

Chong LuDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China.

Yue XinDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China.

Jing ZhouDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China.

Ning ZhangDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China.

Jie MingDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China.

Chunping LiuDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China.

Wei ShiDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China.

Lan ShiDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China.

Xueqin LiDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China.

Xiu NieDepartment of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China.

Tao HuangDepartment of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo demonstrate the relationships between body mass index (BMI) and the clinicopathological features of papillary thyroid microcarcinoma (PTMC) and papillary thyroid carcinoma (PTC).

methodsA total of 810 consecutive patients with PTC (501 patients with PTMC) who underwent total thyroidectomy in 2009-2013 were retrospectively reviewed. Height and weight were used to calculate BMI.

resultsIncreased BMI was strongly associated with i) extrathyroidal invasion (P < 0.001) and advanced TNM stage (P = 0.005) in patients with PTMC (n = 501), and ii) extrathyroidal invasion (P = 0.001), advanced TNM stage (P = 0.001), and multifocality (P = 0.002) in patients with PTC (n = 810). As compared with normal-weight patients with PTMC, obese patients with PTMC had greater risks of extrathyroidal invasion (OR = 5.214, P = 0.0270), and overweight patients with PTMC had greater risks of extrathyroidal invasion (OR = 2.165, P = 0.0013) and advanced TNM stage (OR = 2.019, P = 0.0137). As compared with normal-weight patients with PTC, obese patients with PTC had greater risks of extrathyroidal invasion (OR = 3.101, P = 0.0172), and overweight patients with PTC had greater risks of extrathyroidal invasion (OR = 1.486, P = 0.0279), advanced TNM stage (OR = 1.650, P = 0.0347), and multifocality (OR = 1.651, P = 0.0054).

conclusionsIncreased BMI might elevate the risks of aggressive clinicopathological features, such as extrathyroidal invasion and advanced TNM stage. Obesity control may play an important role in preventing the development of aggressive PTMCs and all PTCs.

Indexed as

Body mass indexprognosisthyroid papillary microcarcinoma

Identifiers

PMID26629173

PMCPMC4659061

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.