ArticleInternational journal of clinical and experimental medicine2015
Impacts of stellate ganglion block on plasma NF-κB and inflammatory factors of TBI patients.
Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Effect of stellate ganglion block on postoperative recovery of gastrointestinal function in patients undergoing surgery with general anaesthesia: a meta-analysis.BMC surgery · 2020Pooled it
- Effects of stellate ganglion block on early brain injury in patients with subarachnoid hemorrhage: a randomised control trial.BMC anesthesiology · 2021Trial
- Effects of Transcutaneous Electrical Acupoint Stimulation on Postoperative Cognitive Decline in Elderly Patients: A Pilot Study.Clinical interventions in aging · 2021Trial
- Observational
- Stellate ganglion block achieves remission of recurrent head-and-neck plaque psoriasis: A case report.The Journal of international medical research · 2026Article
- Towards a nonlinear "neuroimmune gate-model": beyond stellate ganglion block and vagus nerve stimulation.Frontiers in neuroscience · 2026Article
- Three-Month Durability of Bilateral Two-Level Stellate Ganglion Blocks for Traumatic Brain Injury: A Retrospective Analysis.Biomedicines · 2025Article
- Three-Month Durability of Bilateral Two-Level Stellate Ganglion Blocks in Patients with Generalized Anxiety Disorder: A Retrospective Analysis.Brain sciences · 2025Article
- Bilateral Dual Level Cervical Sympathetic Blocks to Treat Post-TBI Sequelae: A Case Report.Case reports in neurological medicine · 2025Article
- Sympathetic nerve block as an add-on therapy for intervention and prevention of cerebral vasospasm after subarachnoid hemorrhage.Frontiers in neurology · 2025Review
- The potential role of stellate ganglion block in impacting the central and peripheral systems: a narrative review.Frontiers in cardiovascular medicine · 2025Review
- The Effect of Bilateral, Two-Level Cervical Sympathetic Chain Blocks on Specific Symptom Clusters for Traumatic Brain Injury, Independent of Concomitant PTSD Symptoms.Brain sciences · 2024Article
- The Successful Use of Bilateral 2-Level Ultrasound-Guided Stellate Ganglion Block to Improve Traumatic Brain Injury Symptoms: A Retrospective Analysis of 23 Patients.Military medicine · 2024Article
- Case report: A new treatment for restless leg syndrome: three cases.Frontiers in neuroscience · 2024Article
- Therapeutic Use of Low-Dose Local Anesthetics in Pain, Inflammation, and Other Clinical Conditions: A Systematic Scoping Review.Journal of clinical medicine · 2023Article
- Stellate Ganglion Block Relieves Long COVID-19 Symptoms in 86% of Patients: A Retrospective Cohort Study.Cureus · 2023Article
- Article
- Article
- Stellate ganglion block reduces inflammation and improves neurological function in diabetic rats during ischemic stroke.Neural regeneration research · 2022Article
- Cervical sympathetic trunk transection alleviates acute lung injury caused by intestinal obstruction via inhibition of phospholipase ABMC anesthesiology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to initially explore the regulatory mechanism of brain function protection of SGB from the view of nerve-endocrine-immune network. 50 patients with traumatic brain injury (TBI) were divided into the SGB treatment group and the control group, the changes of serum IL-6, IL-1β, TNF-α and CGRP levels were detected by ELISA, and the changes of lymphocyte NF-κB protein expression was detected by Western Blot. The control group exhibited the higher expression of IL-6, IL-1β and TNF-α, while the SGB treatment group exhibited various degrees of reduction. On the second day of TBI, the CGRP expression was significantly increased, which was much more significant in the SGB group, and the duration was much longer. The control group exhibited the increased NF-κB p65 and NF-κB p50 after TBI; after the SGB treatment, the NF-κB p65 protein level was significantly reduced, while the NF-κB p50 protein level would not be significantly changed. SGB could chronergically inhibit the excessive inflammatory response in the early post-TBI stage, which suggested that SGB might be involved into the regulation of post-TBI nerve-endocrine-immune system dysfunction.
Indexed as
Identifiers
26629057PMC4658946W2411717520What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.