ArticleThe Journal of rheumatology2016
Patients with Rheumatoid Arthritis have Similar Excellent Outcomes after Total Knee Replacement Compared with Patients with Osteoarthritis.
Open access · greenAbstract readComparative StudyEvaluation Study
In one paragraph
Article in The Journal of rheumatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
5.6field-weighted citation impact, top 4% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Effect of tumour necrosis factor-a inhibitors exposure on surgical site infections in rheumatoid arthritis patients undergoing elective orthopaedic surgery: A meta-analysis.International wound journal · 2024Pooled it
- A systematic review and meta-analysis comparing outcomes following total knee arthroplasty for rheumatoid arthritis versus for osteoarthritis.BMC musculoskeletal disorders · 2023Pooled it
- Long-term knee function and disease activity outcomes of total knee arthroplasty in patients with rheumatoid arthritis: a retrospective study with an average 10-year follow-up.Clinical rheumatology · 2026Article
- Ten-year hip and knee arthroplasty implant survival in patients with inflammatory arthritis receiving methotrexate monotherapy compared with osteoarthritis: a registry-based data linkage study.Scientific reports · 2026Article
- Evolving Characteristics of Rheumatoid Arthritis Patients Receiving Primary Hip or Knee Arthroplasty: A 21-Year Single-Center Trend Analysis (2002-2022).Orthopaedic surgery · 2026Article
- Comparative outcomes of robot-assisted versus conventional TKA in rheumatoid arthritis patients.Journal of orthopaedic surgery and research · 2026Article
- Article
- Exploration of combined factors related to quality of life after knee replacement surgery.PloS one · 2025Article
- Global mapping of institutional and hospital-based (Level II-IV) arthroplasty registries: a scoping review.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Article
- [Outcome of joint replacement in patients with underlying rheumatoid disease].Zeitschrift fur Rheumatologie · 2023Article
- Long-term health related quality of life in total knee arthroplasty.BMC musculoskeletal disorders · 2023Article
- Changes in perioperative C-reactive protein levels in patients with rheumatoid arthritis undergoing total knee arthroplasty in the biologic era.Nagoya journal of medical science · 2022Article
- Perioperative Management of Immunosuppressive Medications in Rheumatic Disease Patients Undergoing Arthroscopy.Current reviews in musculoskeletal medicine · 2021Review
- Acute surgical site infection after total knee arthroplasty in patients with rheumatoid arthritis versus osteoarthritis.Scientific reports · 2021Article
- Arthroplasty Rates Not Increasing in Young Patients With Rheumatoid Arthritis: A National Database Review, 2005 Versus 2014.Arthroplasty today · 2021Article
- Cost-effectiveness of dental antibiotic prophylaxis in total knee arthroplasty recipients with type II diabetes mellitus.Osteoarthritis and cartilage open · 2020Article
- Severe heterotopic ossification post total knee arthroplasty in a patient with rheumatoid arthritis: a case report.Journal of surgical case reports · 2020Article
- The effect of rheumatoid arthritis on patient-reported outcomes following knee and hip replacement: evidence from routinely collected data.Rheumatology (Oxford, England) · 2019Article
- Prevention of Infection in the Perioperative Setting in Patients with Rheumatic Disease Treated with Immunosuppression.Current rheumatology reports · 2019Review
- [Psychological factors in the context of perioperative knee and joint pain: the role of treatment expectations in pain evolvement].Schmerz (Berlin, Germany) · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Susan M GoodmanFrom the Division of Rheumatology, Weill Cornell Medical School, and Department of Medicine, and Department of Orthopedic Surgery, and Department of Biostatistics Core, Hospital for Special Surgery; Albert Einstein College of Medicine; Jacobi Medical Center, New York; North Central Bronx Hospital, Bronx, New York, USA.S.M. Goodman, MD, Associate Professor of Clinical Medicine, Weill Cornell Medicine College, and Associate Attending Physician, Department of Rheumatology, Hospital for Special Surgery; B.K. Johnson, MD, MS, FACR, Assistant Professor of Medicine, Albert Einstein College of Medicine, and Director of Rheumatology, Jacobi Medical Center, and North Central Bronx Hospital; M. Zhang, PhD, Biostatistician, Hospital for Special Surgery; W.T. Huang, MS, Biostatistician, Hospital for Special Surgery; R. Zhu, BA, Research Assistant, Research and Rheumatology, Hospital for Special Surgery; M.P. Figgie, MD, Professor of Orthopedic Surgery, Weill Cornell College of Medicine, and Attending Orthopedic Surgeon, Chief of Surgical Arthritis Service, Hospital for Special Surgery; M.M. Alexiades, MD, Associate Professor of Orthopedic Surgery, Weill Cornell Medicine College, and Associate Attending Physician, Hospital for Special Surgery; L.A. Mandl, MD, MPH, Assistant Professor of Research Medicine, Assistant Professor of Public Health, Weill Cornell Medicine College, and Assistant Attending Physician, Department of Rheumatology, Hospital for Special Surgery. goodmans@hss.edu.
Beverly JohnsonFrom the Division of Rheumatology, Weill Cornell Medical School, and Department of Medicine, and Department of Orthopedic Surgery, and Department of Biostatistics Core, Hospital for Special Surgery; Albert Einstein College of Medicine; Jacobi Medical Center, New York; North Central Bronx Hospital, Bronx, New York, USA.S.M. Goodman, MD, Associate Professor of Clinical Medicine, Weill Cornell Medicine College, and Associate Attending Physician, Department of Rheumatology, Hospital for Special Surgery; B.K. Johnson, MD, MS, FACR, Assistant Professor of Medicine, Albert Einstein College of Medicine, and Director of Rheumatology, Jacobi Medical Center, and North Central Bronx Hospital; M. Zhang, PhD, Biostatistician, Hospital for Special Surgery; W.T. Huang, MS, Biostatistician, Hospital for Special Surgery; R. Zhu, BA, Research Assistant, Research and Rheumatology, Hospital for Special Surgery; M.P. Figgie, MD, Professor of Orthopedic Surgery, Weill Cornell College of Medicine, and Attending Orthopedic Surgeon, Chief of Surgical Arthritis Service, Hospital for Special Surgery; M.M. Alexiades, MD, Associate Professor of Orthopedic Surgery, Weill Cornell Medicine College, and Associate Attending Physician, Hospital for Special Surgery; L.A. Mandl, MD, MPH, Assistant Professor of Research Medicine, Assistant Professor of Public Health, Weill Cornell Medicine College, and Assistant Attending Physician, Department of Rheumatology, Hospital for Special Surgery.
Meng ZhangFrom the Division of Rheumatology, Weill Cornell Medical School, and Department of Medicine, and Department of Orthopedic Surgery, and Department of Biostatistics Core, Hospital for Special Surgery; Albert Einstein College of Medicine; Jacobi Medical Center, New York; North Central Bronx Hospital, Bronx, New York, USA.S.M. Goodman, MD, Associate Professor of Clinical Medicine, Weill Cornell Medicine College, and Associate Attending Physician, Department of Rheumatology, Hospital for Special Surgery; B.K. Johnson, MD, MS, FACR, Assistant Professor of Medicine, Albert Einstein College of Medicine, and Director of Rheumatology, Jacobi Medical Center, and North Central Bronx Hospital; M. Zhang, PhD, Biostatistician, Hospital for Special Surgery; W.T. Huang, MS, Biostatistician, Hospital for Special Surgery; R. Zhu, BA, Research Assistant, Research and Rheumatology, Hospital for Special Surgery; M.P. Figgie, MD, Professor of Orthopedic Surgery, Weill Cornell College of Medicine, and Attending Orthopedic Surgeon, Chief of Surgical Arthritis Service, Hospital for Special Surgery; M.M. Alexiades, MD, Associate Professor of Orthopedic Surgery, Weill Cornell Medicine College, and Associate Attending Physician, Hospital for Special Surgery; L.A. Mandl, MD, MPH, Assistant Professor of Research Medicine, Assistant Professor of Public Health, Weill Cornell Medicine College, and Assistant Attending Physician, Department of Rheumatology, Hospital for Special Surgery.
Wei-Ti HuangFrom the Division of Rheumatology, Weill Cornell Medical School, and Department of Medicine, and Department of Orthopedic Surgery, and Department of Biostatistics Core, Hospital for Special Surgery; Albert Einstein College of Medicine; Jacobi Medical Center, New York; North Central Bronx Hospital, Bronx, New York, USA.S.M. Goodman, MD, Associate Professor of Clinical Medicine, Weill Cornell Medicine College, and Associate Attending Physician, Department of Rheumatology, Hospital for Special Surgery; B.K. Johnson, MD, MS, FACR, Assistant Professor of Medicine, Albert Einstein College of Medicine, and Director of Rheumatology, Jacobi Medical Center, and North Central Bronx Hospital; M. Zhang, PhD, Biostatistician, Hospital for Special Surgery; W.T. Huang, MS, Biostatistician, Hospital for Special Surgery; R. Zhu, BA, Research Assistant, Research and Rheumatology, Hospital for Special Surgery; M.P. Figgie, MD, Professor of Orthopedic Surgery, Weill Cornell College of Medicine, and Attending Orthopedic Surgeon, Chief of Surgical Arthritis Service, Hospital for Special Surgery; M.M. Alexiades, MD, Associate Professor of Orthopedic Surgery, Weill Cornell Medicine College, and Associate Attending Physician, Hospital for Special Surgery; L.A. Mandl, MD, MPH, Assistant Professor of Research Medicine, Assistant Professor of Public Health, Weill Cornell Medicine College, and Assistant Attending Physician, Department of Rheumatology, Hospital for Special Surgery.
Rebecca ZhuFrom the Division of Rheumatology, Weill Cornell Medical School, and Department of Medicine, and Department of Orthopedic Surgery, and Department of Biostatistics Core, Hospital for Special Surgery; Albert Einstein College of Medicine; Jacobi Medical Center, New York; North Central Bronx Hospital, Bronx, New York, USA.S.M. Goodman, MD, Associate Professor of Clinical Medicine, Weill Cornell Medicine College, and Associate Attending Physician, Department of Rheumatology, Hospital for Special Surgery; B.K. Johnson, MD, MS, FACR, Assistant Professor of Medicine, Albert Einstein College of Medicine, and Director of Rheumatology, Jacobi Medical Center, and North Central Bronx Hospital; M. Zhang, PhD, Biostatistician, Hospital for Special Surgery; W.T. Huang, MS, Biostatistician, Hospital for Special Surgery; R. Zhu, BA, Research Assistant, Research and Rheumatology, Hospital for Special Surgery; M.P. Figgie, MD, Professor of Orthopedic Surgery, Weill Cornell College of Medicine, and Attending Orthopedic Surgeon, Chief of Surgical Arthritis Service, Hospital for Special Surgery; M.M. Alexiades, MD, Associate Professor of Orthopedic Surgery, Weill Cornell Medicine College, and Associate Attending Physician, Hospital for Special Surgery; L.A. Mandl, MD, MPH, Assistant Professor of Research Medicine, Assistant Professor of Public Health, Weill Cornell Medicine College, and Assistant Attending Physician, Department of Rheumatology, Hospital for Special Surgery.
Mark FiggieFrom the Division of Rheumatology, Weill Cornell Medical School, and Department of Medicine, and Department of Orthopedic Surgery, and Department of Biostatistics Core, Hospital for Special Surgery; Albert Einstein College of Medicine; Jacobi Medical Center, New York; North Central Bronx Hospital, Bronx, New York, USA.S.M. Goodman, MD, Associate Professor of Clinical Medicine, Weill Cornell Medicine College, and Associate Attending Physician, Department of Rheumatology, Hospital for Special Surgery; B.K. Johnson, MD, MS, FACR, Assistant Professor of Medicine, Albert Einstein College of Medicine, and Director of Rheumatology, Jacobi Medical Center, and North Central Bronx Hospital; M. Zhang, PhD, Biostatistician, Hospital for Special Surgery; W.T. Huang, MS, Biostatistician, Hospital for Special Surgery; R. Zhu, BA, Research Assistant, Research and Rheumatology, Hospital for Special Surgery; M.P. Figgie, MD, Professor of Orthopedic Surgery, Weill Cornell College of Medicine, and Attending Orthopedic Surgeon, Chief of Surgical Arthritis Service, Hospital for Special Surgery; M.M. Alexiades, MD, Associate Professor of Orthopedic Surgery, Weill Cornell Medicine College, and Associate Attending Physician, Hospital for Special Surgery; L.A. Mandl, MD, MPH, Assistant Professor of Research Medicine, Assistant Professor of Public Health, Weill Cornell Medicine College, and Assistant Attending Physician, Department of Rheumatology, Hospital for Special Surgery.
Michael AlexiadesFrom the Division of Rheumatology, Weill Cornell Medical School, and Department of Medicine, and Department of Orthopedic Surgery, and Department of Biostatistics Core, Hospital for Special Surgery; Albert Einstein College of Medicine; Jacobi Medical Center, New York; North Central Bronx Hospital, Bronx, New York, USA.S.M. Goodman, MD, Associate Professor of Clinical Medicine, Weill Cornell Medicine College, and Associate Attending Physician, Department of Rheumatology, Hospital for Special Surgery; B.K. Johnson, MD, MS, FACR, Assistant Professor of Medicine, Albert Einstein College of Medicine, and Director of Rheumatology, Jacobi Medical Center, and North Central Bronx Hospital; M. Zhang, PhD, Biostatistician, Hospital for Special Surgery; W.T. Huang, MS, Biostatistician, Hospital for Special Surgery; R. Zhu, BA, Research Assistant, Research and Rheumatology, Hospital for Special Surgery; M.P. Figgie, MD, Professor of Orthopedic Surgery, Weill Cornell College of Medicine, and Attending Orthopedic Surgeon, Chief of Surgical Arthritis Service, Hospital for Special Surgery; M.M. Alexiades, MD, Associate Professor of Orthopedic Surgery, Weill Cornell Medicine College, and Associate Attending Physician, Hospital for Special Surgery; L.A. Mandl, MD, MPH, Assistant Professor of Research Medicine, Assistant Professor of Public Health, Weill Cornell Medicine College, and Assistant Attending Physician, Department of Rheumatology, Hospital for Special Surgery.
Lisa A MandlFrom the Division of Rheumatology, Weill Cornell Medical School, and Department of Medicine, and Department of Orthopedic Surgery, and Department of Biostatistics Core, Hospital for Special Surgery; Albert Einstein College of Medicine; Jacobi Medical Center, New York; North Central Bronx Hospital, Bronx, New York, USA.S.M. Goodman, MD, Associate Professor of Clinical Medicine, Weill Cornell Medicine College, and Associate Attending Physician, Department of Rheumatology, Hospital for Special Surgery; B.K. Johnson, MD, MS, FACR, Assistant Professor of Medicine, Albert Einstein College of Medicine, and Director of Rheumatology, Jacobi Medical Center, and North Central Bronx Hospital; M. Zhang, PhD, Biostatistician, Hospital for Special Surgery; W.T. Huang, MS, Biostatistician, Hospital for Special Surgery; R. Zhu, BA, Research Assistant, Research and Rheumatology, Hospital for Special Surgery; M.P. Figgie, MD, Professor of Orthopedic Surgery, Weill Cornell College of Medicine, and Attending Orthopedic Surgeon, Chief of Surgical Arthritis Service, Hospital for Special Surgery; M.M. Alexiades, MD, Associate Professor of Orthopedic Surgery, Weill Cornell Medicine College, and Associate Attending Physician, Hospital for Special Surgery; L.A. Mandl, MD, MPH, Assistant Professor of Research Medicine, Assistant Professor of Public Health, Weill Cornell Medicine College, and Assistant Attending Physician, Department of Rheumatology, Hospital for Special Surgery.
Hospital for Special Surgery · USCornell University · US
Funding
Clinical and Translational Science CenterUL1TR000457 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI IMPERATO-MCGINLEY, JULIANNE L · 2012 to 2016
$46.0MThe Centers for Education and Research on Therapeutics *U18HS016075 · AHRQ · WEILL MEDICAL COLL OF CORNELL UNIV · PI MUSHLIN, ALVIN MUSHLIN · 2006 to 2010
$4.0MAHRQ HHS U18 HS016075NCATS NIH HHS UL1 TR000457NCATS NIH HHS UL1-TR000457-06
Abstract
objectiveAlthough new treatments for rheumatoid arthritis (RA) are extremely effective in preventing disease progression, rates of total knee replacement (TKR) continue to rise. The ongoing need for TKR is problematic, especially as functional outcomes in patients with RA have been reported to be worse than in patients with osteoarthritis (OA). The purpose of this study is to assess pain, function, and quality of life 2 years after TKR in contemporary patients with RA compared with patients with OA.
methodsPrimary TKR cases enrolled between May 1, 2007 and July 1, 2010 in a single institution TKR registry were eligible for this study. Validated RA cases were compared with OA at baseline and at 2 years.
resultsWe identified 4456 eligible TKR, including 136 RA. Compared with OA, RA TKR had significantly worse preoperative Western Ontario and McMaster Universities Osteoarthritis Index pain (55.9 vs 46.6, p < 0.0001) and function (58.7 vs 47.3, p < 0.0001); however, there were no differences at 2 years. Within RA, there was no difference for patients who were treated with biologic disease-modifying antirheumatic drugs versus those who did not in pain (p = 0.41) or function (p = 0.39) at 2 years. In a multivariate regression, controlling for multiple potential confounders, there was no independent association of RA with 2-year pain (p = 0.18) or function (p = 0.71). Satisfaction was high for both RA and OA.
conclusionPatients with RA undergoing primary TKR have excellent 2-year outcomes, comparable with OA, in spite of worse preoperative pain and function. In this contemporary cohort, RA is not an independent risk factor for poor outcomes.
Indexed as
Quality of LifeAgedAnalysis of VarianceArthritis, RheumatoidArthroplasty, Replacement, KneeCohort StudiesFemaleHumansKnee JointLinear ModelsLogistic ModelsMaleMiddle AgedMultivariate AnalysisOsteoarthritis, KneePain MeasurementARTHROPLASTYDISEASE-MODIFYING ANTIRHEUMATIC DRUGSOSTEOARTHRITISRHEUMATOID ARTHRITIS
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