ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2016
Metal coverage ratio of pipeline embolization device for treatment of unruptured aneurysms: Reality check.
Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Comparison of intra-aneurysmal flow modification using optical flow imaging to evaluate the performance of Evolve and Pipeline flow diverting stents.Journal of neurointerventional surgery · 2020Trial
- AneuGuidederived metal coverage ratio and pore density in Pipeline embolization devices: validation against VasoCT and association with aneurysm occlusion.Quantitative imaging in medicine and surgery · 2026Article
- Traumatic vertebral artery transection injury: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Initial Experience with the New DERIVOBrain sciences · 2024Article
- Endovascular Treatment of Intracranial Aneurysm: The Importance of the Rheological Model in Blood Flow Simulations.Bioengineering (Basel, Switzerland) · 2024Article
- Overlapped Double-Layer Micromesh Stents for Giant Extracranial Internal Carotid Artery Aneurysm.Journal of neuroendovascular therapy · 2023Article
- Surpass Evolve Flow Diverter for the Treatment of Intracranial Aneurysm: A Systematic Review.Brain sciences · 2022Review
- A multicenter retrospective controlled study of the Pipeline™ and Tubridge™ Flow Diverter devices for intracranial wide-necked aneurysms.Frontiers in neurology · 2022Article
- In-silico trial of intracranial flow diverters replicates and expands insights from conventional clinical trials.Nature communications · 2021Article
- Trans-Cell Technique through Mesh of Pipeline Embolization Device: A Case Report.Journal of neuroendovascular therapy · 2021Article
- Neck Location on the Outer Convexity is a Predictor of Incomplete Occlusion in Treatment with the Pipeline Embolization Device: Clinical and Angiographic Outcomes.AJNR. American journal of neuroradiology · 2021Article
- Hydrodynamic Resistance of Intracranial Flow-Diverter Stents: Measurement Description and Data Evaluation.Cardiovascular engineering and technology · 2020Article
- On Flow Diversion: The Changing Landscape of Intracerebral Aneurysm Management.AJNR. American journal of neuroradiology · 2019Review
- Optimizing contrast-enhanced cone-beam CT protocol to facilitate simultaneous visualization of neurovascular pathologies and surrounding structures of interest.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2019Article
- Toward Better Understanding of Flow Diversion in Bifurcation Aneurysms.AJNR. American journal of neuroradiology · 2018Article
- In vitro digital subtraction angiographic evaluation of flow diverters in a patient-specific aneurysm.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2017Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeThe metal coverage ratio (MCR) of a flow diverter influences the intra-aneurysmal hemodynamics; a high MCR will occlude an aneurysm early, while a low MCR may delay aneurysm occlusion. The true MCR of a pipeline embolization device (PED) could be lower due to oversize, device deformation, or aneurysm location. In this study deviation of the true MCR from the nominal MCR is assessed and whether their difference affects aneurysm occlusion rate is determined.
methodsA total of 40 consecutive patients, each of them treated by one PED for their aneurysms at the internal carotid artery (ICA), were retrospectively analyzed. The DynaCT images of these deployed PEDs were used to determine their true dimensions and estimate three MCRs (local, mean, and nominal). These data were compared in two groups of patients who had different aneurysm outcomes at six months.
resultsThe difference in the local MCR between two groups is small, but statistically significant (24.5% vs 21.6%, p=05). The local MCR is consistently lower than the nominal MCRs (23.2% vs 30.2%, p<0.001); however, the difference between the mean and local MCRs is small (23.9% vs 23.2%).
conclusionsAn expectation that a PED can achieve a MCR of 30% may not be reasonable. Device oversize and deformation during deployment lower the local MCR by 5-7%. A lowered MCR affects the aneurysm occlusion rate at six months.
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