Evidence map›Paper›PMID 26628287›Full record

ArticleCancer medicine2016

Recent decline in prostate cancer incidence in the United States, by age, stage, and Gleason score.

Kimberly A Herget, Darshan P Patel, Heidi A Hanson, Carol Sweeney, William T Lowrance

Abstract read
In one paragraph

Article in Cancer medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Deep Sequencing Reveals Novel Mutations inInternational journal of molecular sciences · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Putting patients first to redefine prostate cancer classifications.Journal of the National Cancer Institute · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Management of prostate cancer patients during COVID-19 pandemic.Prostate cancer and prostatic diseases · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kimberly A HergetUtah Cancer Registry, University of Utah, Salt Lake City, Utah.
Darshan P PatelDivision of Urology, Department of Surgery, University of Utah, Salt Lake City, Utah.
Heidi A HansonHuntsman Cancer Institute, Salt Lake City, Utah.
Carol SweeneyUtah Cancer Registry, University of Utah, Salt Lake City, Utah.
William T LowranceDivision of Urology, Department of Surgery, University of Utah, Salt Lake City, Utah.

Funding

UTAH REGIONAL CANCER CENTERP30CA042014 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI CORNELIA M ULRICH · 1986 to 2026
$72.6M
NCI NIH HHS P30 CA042014NCI NIH HHS P30CA042014
6 · The paper itself

Abstract

Prostate cancer incidence is sensitive to screening practices, however the impact of recent screening recommendations from the United States Preventative Services Task Force on prostate cancer incidence by age, stage, race, and Gleason score is unknown. This study described the timing and magnitude of changes in prostate cancer incidence trends in the United States by month of diagnosis, and evaluated trends by age, Gleason score, and stage at diagnosis. We analyzed prostate cancer incidence trends using Surveillance, Epidemiology, and End Results (SEER) program data for men diagnosed with invasive prostate cancer from 2007 through 2012. JoinPoint analysis was used to detect changes in the rate of annual percent change (APC) in prostate cancer incidence for all diagnoses and by age, Gleason score, race, and stage. Prostate cancer incidence declined at an estimated -19.6% APC beginning May 2011. This decline was observed in all age groups. Low-grade tumors (Gleason score ≤6) showed a steeper decline (-29.1% APC) than high-grade tumors (Gleason score 8-10: -10.8% APC). Only stage I/II and stage III tumors saw declines (-24.2% and -16.7% APC, respectively). A sharp decline in prostate cancer incidence began before release of the United States Preventative Services Task Force October 2011 draft and May 2012 final screening recommendation. The greatest change occurred with incidence of low-grade tumors, although there is concern that some high-grade tumors may now go undetected.

Indexed as

Age DistributionHumansIncidenceMaleNeoplasm GradingNeoplasm StagingPopulation SurveillanceProstatic NeoplasmsSEER ProgramUnited StatesEarly detection of cancerincidenceprostate specific antigenprostatic neoplasmsSEER programtrends

Identifiers

PMID26628287
PMCPMC4708896

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.