Evidence map›Paper›PMID 26628206›Full record

Trial reportThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2015

Effects of Problem-Solving Therapy and Clinical Case Management on Disability in Low-Income Older Adults.

Patricia A Areán, Patrick J Raue, Charles McCulloch, Dora Kanellopoulos, Joanna K Seirup, Samprit Banerjee, Dimitris N Kiosses, Eleanor Dwyer, George S Alexopoulos

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00540865 (Case Management and Problem Solving Therapy for Depressed, Homebound, Low-Income Elders), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00540865 nacompletednot on this map

Case Management and Problem Solving Therapy for Depressed, Homebound, Low-Income Elders

TypeinterventionalSponsorWeill Medical College of Cornell UniversityRan2007 to 2013Enrolled187ConditionsDepressionArmsProblem-solving therapy (PST), Case management (CM)
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Effectiveness of Shared Decision-Making for Elderly Depressed Minority Primary Care Patients.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2019
    Trial
  4. Depression Agency-Based Collaborative: Effect of Problem-Solving Therapy on Risk of Common Mental Disorders in Older Adults With Home Care Needs.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2019
    Trial
  5. Trial
  6. Article
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Patricia A AreánDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA. Electronic address: parean@uw.edu.
Patrick J RaueDepartment of Public Health, Weill Cornell Medical College, New York, NY.
Charles McCullochDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA.
Dora KanellopoulosDepartment of Public Health, Weill Cornell Medical College, New York, NY.
Joanna K SeirupDepartment of Public Health, Weill Cornell Medical College, New York, NY.
Samprit BanerjeeDepartment of Public Health, Weill Cornell Medical College, New York, NY.
Dimitris N KiossesDepartment of Public Health, Weill Cornell Medical College, New York, NY.
Eleanor DwyerSan Mateo Department of Public Health, San Mateo, CA.
George S AlexopoulosDepartment of Public Health, Weill Cornell Medical College, New York, NY.
Cornell University · USSan Mateo County Health System · USUniversity of California, San Francisco · USUniversity of Washington · US

Funding

Research Methods CoreP30MH085943 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI ALEXOPOULOS, GEORGE S · 2009 to 2013
$9.2M
PST in Geriatric Depression with Executive DysfunctionR01MH063982 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AREAN, PATRICIA A. · 2002 to 2006
$1.9M
Treating Depression in Low-Income Elderly with CIND/AMCIK24MH074717 · NIMH · UNIVERSITY OF WASHINGTON · PI AREAN, PATRICIA A. · 2005 to 2016
$1.7M
Case Management and PST for Depressed Homebound Low-Income EldersR01MH075900 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AREAN, PATRICIA A. · 2007 to 2011
$1.6M
Case Management and PST for Depressed Homebound Low-Income EldersR01MH075897 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI ALEXOPOULOS, GEORGE S · 2007 to 2011
$1.5M
NIMH NIH HHS K24 MH074717NIMH NIH HHS P30 MH085943NIMH NIH HHS R01 MH063982NIMH NIH HHS R01 MH075897NIMH NIH HHS R01 MH075900
6 · The paper itself

Abstract

objectiveTo test the following hypotheses: (1) Clinical case management integrated with problem-solving therapy (CM-PST) is more effective than clinical case management alone (CM) in improving functional outcomes in disabled, impoverished patients and (2) improvement in depression, self-efficacy, and problem-solving skills mediates improvement of disability.

methodsUsing a randomized controlled trial with a parallel design, 271 individuals were screened and 171 were randomized to 12 weekly sessions of either CM or CM-PST at 1:1 ratio. Raters were blind to patients' assignments. Participants were at least age 60 years with major depression, had at least one disability, were eligible for home-based meals services, and had income no more than 30% of their counties' median. The WHO Disability Assessment Scale was used.

resultsBoth interventions resulted in improved functioning by 12 weeks (t = 4.28, df = 554, p = 0.001), which was maintained until 24 weeks. Contrary to hypothesis, CM was noninferior to CM-PST (one-sided p = 0.0003, t = -3.5, df = 558). Change in disability was not affected by baseline depression severity, cognitive function, or number of unmet social service needs. Improvements in self efficacy (t = -2.45, df = 672, p = 0.021), problem-solving skill (t = -2.44, df = 546, p = 0.015), and depression symptoms (t = 2.25, df = 672, p = .025) by week 9 predicted improvement in function across groups by week 12.

conclusionCM is noninferior to CM-PST for late-life depression in low-income populations. The effect of these interventions occur early, with benefits in functional status maintained as long as 24 weeks after treatment initiation (clinicaltrials.gov; NCT00540865).

Indexed as

PovertyProblem SolvingAgedCase ManagementDisability EvaluationHumansPersons with DisabilitiesPsychiatric Status Rating ScalesPsychotherapyTreatment Outcomecase managementDisabilitylate-life depression

Identifiers

PMID26628206
PMCPMC6033321
OpenAlexW2049292543

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.