Evidence map›Paper›PMID 26628068›Full record

ArticleMalaria journal2015

Prescription practices for malaria in Mozambique: poor adherence to the national protocols for malaria treatment in 22 public health facilities.

Cristolde A Salomão, Jahit Sacarlal, Baltazar Chilundo, Eduardo Samo Gudo

Open access · goldAbstract read
In one paragraph

Article in Malaria journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Cristolde A SalomãoNational Institute of Health, Ministry of Health, Field Epidemiology and Laboratory Training Program, Av Eduardo Mondlane 1008, 2nd floor, PO Box 264, Maputo, Mozambique. todysalo@gmail.com.
Jahit SacarlalDepartment of Microbiology, Faculty of Medicine, Eduardo Mondlane University, Av. Salvador Allende 702, PO Box 257, Maputo, Mozambique. jahityash2002@yahoo.com.br.
Baltazar ChilundoDepartment of Community Health, Faculty of Medicine, Eduardo Mondlane University, Av. Salvador Allende 702, PO Box 257, Maputo, Mozambique. batazar.chilundo@gmail.com.
Eduardo Samo GudoNational Institute of Health, Ministry of Health, Field Epidemiology and Laboratory Training Program, Av Eduardo Mondlane 1008, 2nd floor, PO Box 264, Maputo, Mozambique. esamogudojr@gmail.com.
Eduardo Mondlane University · MZMinistry of Health · MZ

Funding

CGH CDC HHS U2R GH000046PHS HHS U2RGH000046
6 · The paper itself

Abstract

backgroundCurrent World Health Organization and national protocols recommend the 'test and treat' strategy for the management of uncomplicated malaria, to reduce over prescription of artemisinin-based combination treatment (ACT). Therefore, adherence to these protocols varies in different sub-Saharan African countries and no information is available for Mozambique. This study was conducted with the aim to evaluate the prescription practices of ACT in Mozambique.

methodsRetrospective audit of medical records corresponding to the period between July and December 2011 was conducted in 22 health units across 11 provinces in Mozambique. Two health units were selected per province according to availability of laboratory data (performing microscopy and rapid diagnostics testing-RDT or RDT only) and geographic setting (rural versus urban). At each facility, demographic data, laboratory results (blood smear or RDT), and prescription of ACT were all collected from the existing records.

resultsBetween July and December 2011, a total of 61,730 cases were tested for malaria, of which 42.7 % (26,369/61,730) were positive. A total of 35.361 patients were malaria negative, and ACT was prescribed to 72.0 % (25.448/35.361) of them. Prescription of ACT to malaria negative patients was higher in the central region of the country as compared to the northern and southern (81.1 % in the central region versus 72.4 and 63.7 % in the northern and southern, respectively, p = 0.000) and in urban settings (88.7 % in rural versus 58.0 % in urban settings, p = 0.000). Stock out of RDT was observed in six (27.3 %) of the health facilities. When no RDT was available, patients were empirically treated with ACT.

conclusionFindings from this study demonstrate that health care worker's adherence to the new guidelines for malaria treatment is poor in Mozambique and prescription of ACT to malaria negative patients remains very high. Enhanced training and supervision activities, community education and external quality assurance might lead to significant improvements in the clinician's adherence to the new guideline for malaria treatment in Mozambique.

Indexed as

Guideline AdherencePractice Patterns, Physicians'PrescriptionsAntimalarialsArtemisininsHealth FacilitiesHumansLactonesMalariaMozambiqueRetrospective StudiesAntimalarialsartemisinArtemisininsLactones

Identifiers

PMID26628068
PMCPMC4667420
OpenAlexW2186882279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.