Evidence map›Paper›PMID 26627985›Full record

ArticleGenome research2016

H3ABioNet, a sustainable pan-African bioinformatics network for human heredity and health in Africa.

Nicola J Mulder, Ezekiel Adebiyi, Raouf Alami, Alia Benkahla, James Brandful, Seydou Doumbia, Dean Everett, Faisal M Fadlelmola, Fatima Gaboun, Simani Gaseitsiwe and 27 more

Open access · hybridAbstract read
In one paragraph

Article in Genome research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed, 1 synthesis or guideline pooled it, 156 citations in OpenAlex.

  1. Pooled it
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  3. From molecules to minds: Integrative multi-omics in psychiatry.Journal of mood and anxiety disorders · 2026
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41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors at 20 institutions in 18 countries.

Nicola J MulderComputational Biology Group, Department of Integrative Biomedical Sciences, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa 7925;
Ezekiel AdebiyiCovenant University Bioinformatics Research (CUBRe) and Department of Computer and Information Sciences, Covenant University, Ota, Ogun State, Nigeria, P.M.B. 1023;
Raouf AlamiCentre National de Transfusion Sanguine, Rabat, Morocco 10100;
Alia BenkahlaInstitute Pasteur of Tunis, Tunis, Tunisia 1002;
James BrandfulNoguchi Memorial Institute for Medical Research, University of Ghana, Ghana, LG;
Seydou DoumbiaUniversity of Sciences, Techniques and Technology of Bamako, Bamako, Mali BPE 3206;
Dean EverettMalawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi, 3/Institute of Infection and Global Health, University of Liverpool, Liverpool L69 3BX, United Kingdom;
Faisal M FadlelmolaCentre for Bioinformatics and Systems Biology, Faculty of Science, University of Khartoum/Future University of Sudan, Khartoum, Sudan 11115;
Fatima GabounInstitut National de Recherche Agronomique, Rabat, Morocco 10000;
Simani GaseitsiweBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana;
Hassan GhazalUniversity Mohammed First, Oujda, Morocco 60000;
Scott HazelhurstSydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, Johannesburg, South Africa 2193;
Winston HideHarvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA/Sheffield Institute for Translational Neuroscience, Department of Neuroscience, University of Sheffield, Sheffield S10 2HQ, United Kingdom;
Azeddine IbrahimiFaculté de Médecine et de Pharmacie de Rabat, Université Mohammed V Souissi, Rabat, Morocco 10100;
Yasmina Jaufeerally FakimUniversity of Mauritius, Reduit, Mauritius 80837;
C Victor JongeneelNational Center for Supercomputing Applications and Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA;
Fourie JoubertDepartment of Biochemistry, University of Pretoria, Pretoria, South Africa 0083;
Samar KassimMedical Biochemistry and Molecular Biology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt 11566;
Jonathan KayondoUganda Virus Research Institute, Entebbe, Uganda 31301;
Judit KumuthiniCentre for Proteomic and Genomic Research, Cape Town, South Africa 7925;
Sylvester LyantagayeUniversity of Dar es Salaam, Dar es Salaam, Tanzania, 73;
Julie MakaniMuhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania 00255;
Ahmed Mansour AlzohairyGenetics Department, Faculty of Agriculture, Zagazig University, Sharkia, Egypt 44519;
Daniel MasigaInternational Centre of Insect Physiology and Ecology, Nairobi, Kenya 00100;
Ahmed MoussaAbdelmalek Essaadi University, ENSA, Tangier, Morocco 90000;
Oyekanmi NashNational Biotechnology Development Agency, Abuja, Nigeria 10099;
Odile Ouwe Missi Oukem-BoyerCentre de Recherche Medicale et Sanitaire, Niamey, Niger, BP 10887;
Ellis Owusu-DaboKumasi Centre for Collaborative Research in Tropical Medicine/Kwame Nkrumah University of Science and Technology, Kumasi, Ghana, PMB;
Sumir PanjiComputational Biology Group, Department of Integrative Biomedical Sciences, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa 7925;
Hugh PattertonUniversity of the Free State, Bloemfontein, South Africa 9300;
Fouzia RadouaniInstitut Pasteur du Maroc, Casablanca, Maroc, Morocco 20360;
Khalid SadkiFaculty of Sciences of Rabat, University Mohammed V of Rabat, Rabat, Morocco 10000;
Fouad SeghrouchniInstitut National d'Hygiène, Rabat, Morocco 10090;
Özlem Tastan BishopResearch Unit in Bioinformatics, Department of Biochemistry and Microbiology, Rhodes University, Grahamstown, South Africa 6140;
Nicki TiffinSouth African National Bioinformatics Institute/Medical Research Council of South Africa Bioinformatics Unit, University of the Western Cape, Cape Town, South Africa 7530;
Nzovu UlengaManagement and Development for Health, Dar es Salaam, Tanzania, 61.
H3ABioNet Consortium
Mohammed V University · MAUniversity of Cape Town · ZAAbdelmalek Essaâdi University · MAAfrican Organisation for Research and Training in Cancer · ZAAin Shams University · EGBotswana Harvard AIDS Institute Partnership · BWCentre de Recherche Médicale et Sanitaire · NECovenant University · NGInstitut Agronomique et Vétérinaire Hassan II · MAInstitut National de la Transfusion Sanguine · FRInstitut National d'Hygiène du Maroc · MAInstitut Pasteur de Tunis · TNInstitut Pasteur du Maroc · MAInternational Centre of Insect Physiology and Ecology · KEKwame Nkrumah University of Science and Technology · GHManagement and Development for Health · TZMohamed I University · MAMuhimbili University of Health and Allied Sciences · TZNational Primary Health Care Development Agency · NGRhodes University · ZA

Funding

H3ABioNet: a sustainable African Bioinformatics Network for H3AfricaU41HG006941 · NHGRI · UNIVERSITY OF CAPE TOWN · PI MULDER, NICOLA · 2012 to 2017
$14.8M
Sickle Africa Data Coordinating CenterU24HL135600 · NHLBI · UNIVERSITY OF CAPE TOWN · PI MULDER, NICOLA, WONKAM, AMBROISE · 2017 to 2025
$8.6M
Exploring Perspectives on Genomics and Sickle Cell Public Health InterventionsU01HG007459 · NHGRI · UNIVERSITY OF CAPE TOWN · PI WONKAM, AMBROISE · 2013 to 2016
$622k
NHGRI NIH HHS U01 HG007459NHGRI NIH HHS U41 HG006941NHGRI NIH HHS U41HG006941NHLBI NIH HHS U24 HL135600Wellcome Trust 093727Wellcome Trust 095009
6 · The paper itself

Abstract

The application of genomics technologies to medicine and biomedical research is increasing in popularity, made possible by new high-throughput genotyping and sequencing technologies and improved data analysis capabilities. Some of the greatest genetic diversity among humans, animals, plants, and microbiota occurs in Africa, yet genomic research outputs from the continent are limited. The Human Heredity and Health in Africa (H3Africa) initiative was established to drive the development of genomic research for human health in Africa, and through recognition of the critical role of bioinformatics in this process, spurred the establishment of H3ABioNet, a pan-African bioinformatics network for H3Africa. The limitations in bioinformatics capacity on the continent have been a major contributory factor to the lack of notable outputs in high-throughput biology research. Although pockets of high-quality bioinformatics teams have existed previously, the majority of research institutions lack experienced faculty who can train and supervise bioinformatics students. H3ABioNet aims to address this dire need, specifically in the area of human genetics and genomics, but knock-on effects are ensuring this extends to other areas of bioinformatics. Here, we describe the emergence of genomics research and the development of bioinformatics in Africa through H3ABioNet.

Indexed as

Health PromotionAfricaBlack PeopleComputational BiologyComputer SystemsGenetics, MedicalGenetic VariationGenomicsHumans

Identifiers

PMID26627985
PMCPMC4728379
OpenAlexW2188414616

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.