ArticleHealth and quality of life outcomes2015
A qualitative examination of the content validity of the EQ-5D-5L in patients with type 2 diabetes.
Article in Health and quality of life outcomes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06092827 (Feasibility and Acceptability Study of a Non Weight-bearing Physical Activity Program for People With Diabetic Foot Ulceration), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Feasibility and Acceptability Study of a Non Weight-bearing Physical Activity Program for People With Diabetic Foot Ulceration (DB ACTIV)
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Patient-reported outcome measures for assessing health-related quality of life in people with type 2 diabetes: A systematic review.Reviews in endocrine & metabolic disorders · 2022Pooled it
- Content Validity of Two Generic Preference-Based Measures in Retinitis Pigmentosa, Including X-Linked Retinitis Pigmentosa.PharmacoEconomics - open · 2026Article
- The psychometric performance of the EQ-5D-5L composite and component items in the U.S. General population and by age group.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- A Qualitative Examination of the Content Validity of the EQ-5D-5L and EQ-5D-Y-3L in Adult and Paediatric Patients With Duchenne Muscular Dystrophy.Health expectations : an international journal of public participation in health care and health policy · 2025Article
- Evaluating the content validity of the EQ-5D-Y for Chinese children and adolescents.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- A framework for extending the health-related quality adjusted life year by combining instruments.Health and quality of life outcomes · 2025Article
- What difference does multiple imputation make in longitudinal modeling of EQ-5D-5L data? Empirical analyses of simulated and observed missing data patterns.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- Validity of EQ-5D-5L health-related quality of life questionnaire in self-reported diabetes: evidence from a general population survey.Health and quality of life outcomes · 2021Article
- Acceptability of the health-related quality of life instrument EQ-5D-Y-5L among patients in child and adolescent psychiatric inpatient care.Acta paediatrica (Oslo, Norway : 1992) · 2021Article
- EQ-5D-5L-based quality of life normative data for patients with self-reported diabetes in Poland.PloS one · 2021Article
- Reporting and valuing one's own health: a think aloud study using EQ-5D-5L, EQ VAS and a time trade-off question among patients with a chronic condition.Health and quality of life outcomes · 2020Article
- Rasch analysis of the long-term conditions questionnaire (LTCQ) and development of a short-form (LTCQ-8).Health and quality of life outcomes · 2020Article
- Article
- Estimating EQ-5D utilities based on the Short-Form Long Term Conditions Questionnaire (LTCQ-8).Health and quality of life outcomes · 2020Article
- Longitudinal assessment of utilities in patients with migraine: an analysis of erenumab randomized controlled trials.Health and quality of life outcomes · 2019Article
- Variation in the apparent importance of health-related problems with the instrument used to measure patient welfare.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018Article
- Is the EQ-5D fit for purpose in asthma? Acceptability and content validity from the patient perspective.Health and quality of life outcomes · 2018Article
- Qualitative assessment of the primary care outcomes questionnaire: a cognitive interview study.BMC health services research · 2018Article
- Long-Term Conditions Questionnaire (LTCQ): initial validation survey among primary care patients and social care recipients in England.BMJ open · 2017Article
- "When I saw walking I just kind of took it as wheeling": interpretations of mobility-related items in generic, preference-based health state instruments in the context of spinal cord injury.Health and quality of life outcomes · 2016Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe EQ-5D is frequently used to derive utilities for patients with type 2 diabetes (T2D). Despite widely available quantitative psychometric data on the EQ-5D, little is known about content validity in this population. Thus, the purpose of this qualitative study was to examine content validity of the EQ-5D in patients with T2D.
methodsPatients with T2D in the UK completed concept elicitation interviews, followed by administration of the EQ-5D-5L and cognitive interviewing focused on the instrument's relevance, clarity, and comprehensiveness.
resultsA total of 25 participants completed interviews (52.0 % male; mean age = 53.5 years). Approximately half (52 %) reported that the EQ-5D-5L was relevant to their experience with T2D. When asked if each individual item was relevant to their experience with T2D, responses varied widely (24.0 % said the self-care item was relevant; 68.0 % said the anxiety/depression item was relevant). Participants frequently said items were not relevant to themselves, but could be relevant to patients with more severe diabetes. Most participants (92.0 %) reported that T2D and/or its treatment/monitoring requirements had an impact on their quality of life that was not captured by the EQ-5D-5L. Common missing concepts included food awareness/restriction (n = 13, 52.0 %); activities (n = 11, 44.0 %); emotional functioning other than depression/anxiety (n = 8, 32.0 %); and social/relationship functioning (n = 8, 32.0 %).
conclusionsThe results highlight strengths and potential limitations of the EQ-5D-5L, including missing content that could be important for some patients with T2D. Suggestions for addressing limitations are provided.
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