Evidence map›Paper›PMID 26627865›Full record

ReviewNeuroscience and biobehavioral reviews2016

Comparing brains by matching connectivity profiles.

Rogier B Mars, Lennart Verhagen, Thomas E Gladwin, Franz-Xaver Neubert, Jerome Sallet, Matthew F S Rushworth

Abstract readReview
In one paragraph

Review in Neuroscience and biobehavioral reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  11. Timescales of learning in prefrontal cortex.Nature reviews. Neuroscience · 2024
    Review
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  15. Individuals who see the good in the bad engage distinctive default network coordination during post-encoding rest.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
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  18. Review
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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rogier B MarsDonders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen 6525 EZ, The Netherlands; Centre for Functional MRI of the Brain, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK. Electronic address: r.mars@donders.ru.nl.
Lennart VerhagenDepartment of Experimental Psychology, University of Oxford, Tinbergen Building, South Parks Road, Oxford OX1 3UD, UK.
Thomas E GladwinMilitary Mental Health Research Centre, Ministry of Defence, The Netherlands and Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands.
Franz-Xaver NeubertDepartment of Experimental Psychology, University of Oxford, Tinbergen Building, South Parks Road, Oxford OX1 3UD, UK.
Jerome SalletDepartment of Experimental Psychology, University of Oxford, Tinbergen Building, South Parks Road, Oxford OX1 3UD, UK.
Matthew F S RushworthCentre for Functional MRI of the Brain, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK; Department of Experimental Psychology, University of Oxford, Tinbergen Building, South Parks Road, Oxford OX1 3UD, UK.

Funding

Medical Research Council G0700399Medical Research Council G0902373Wellcome Trust 105651
6 · The paper itself

Abstract

The great promise of comparative neuroscience is to understand why brains differ by investigating the relations between variations in the organization of different brains, their evolutionary history, and their current ecological niche. For this approach to be successful, the organization of different brains needs to be quantifiable. Here, we present an approach to formally comparing the connectivity of different cortical areas across different brains. We exploit the fact that cortical regions can be characterized by the unique pattern of connectivity, the so-called connectivity fingerprint. By comparing connectivity fingerprints between cortical areas in the human and non-human primate brain we can identify between-species homologs, but also illustrate that is driving differences between species. We illustrate the approach by comparing the organization of the frontal cortex between humans and macaques, showing general similarities combined with some differences in the lateral frontal pole.

Indexed as

AnimalsBiological EvolutionBrainHumansNeural PathwaysSpecies SpecificityBrain architectureComparative neuroscienceConnectivityConnectivity fingerprintPrimate

Identifiers

PMID26627865
PMCPMC6485474

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.