Evidence map›Paper›PMID 26626916›Full record

ArticleCurrent obesity reports2014

Androgens, body fat Distribution and Adipogenesis.

Mouna Zerradi, Julie Dereumetz, Marie-Michèle Boulet, André Tchernof

Abstract read
PubMed Publisher
In one paragraph

Article in Current obesity reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
  6. Article
  7. Review
  8. Article
  9. The Novel-miR-659/Animals : an open access journal from MDPI · 2022
    Article
  10. Adrenal Androgen Predictive Effects on Clinical and Metabolic Abnormalities of Polycystic Ovary Syndrome.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Sex Differences in Adipose Tissue Function.Endocrinology and metabolism clinics of North America · 2020
    Review
  15. Review
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mouna ZerradiEndocrinology and Nephrology, CHU de Quebec Research Center, 2705 Laurier Blvd. R-4779, Quebec City, PQ, Canada, G1V 4G2.
Julie DereumetzEndocrinology and Nephrology, CHU de Quebec Research Center, 2705 Laurier Blvd. R-4779, Quebec City, PQ, Canada, G1V 4G2.
Marie-Michèle BouletEndocrinology and Nephrology, CHU de Quebec Research Center, 2705 Laurier Blvd. R-4779, Quebec City, PQ, Canada, G1V 4G2.
André TchernofEndocrinology and Nephrology, CHU de Quebec Research Center, 2705 Laurier Blvd. R-4779, Quebec City, PQ, Canada, G1V 4G2. andre.tchernof@crchul.ulaval.ca.
Université Laval · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Androgens are regulators of important adipocyte functions such as adipogenesis, lipid storage, and lipolysis. Through depot-specific impact on the cells of each fat compartment, androgens could modulate body fat distribution patterns in humans. Testosterone and dihydrotestosterone have been shown to inhibit the differentiation of preadipocytes to lipid-storing adipocytes in several models including primary cultures of human adipocytes from both men and women. Androgen effects have also been observed on some markers of lipid metabolism such as LPL activity, fatty acid uptake, and lipolysis. Possible depot-specific and sex-specific effects have been observed in some but not all models. Transformation of androgen precursors to active androgens or their inactivation by enzymes that are expressed and functional in adipose tissue may contribute to modulate the local availability of active hormones. These phenomena, along with putative depot-specific interactions with glucocorticoids may contribute to human body fat distribution patterns.

Indexed as

Adipose tissueAndrogenDHTPCOSTestosterone

Identifiers

PMID26626916
OpenAlexW2144500742

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.