Evidence map›Paper›PMID 26626785›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2017

Myocardial

Anna De Rosa, Teresa Pellegrino, Sabina Pappatà, Maria Teresa Pellecchia, Silvio Peluso, Francesco Saccà, Paolo Barone, Alberto Cuocolo, Giuseppe De Michele

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Autonomic disorders and myocardial 123I-metaiodobenzylguanidine scintigraphy in Huntington's disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  3. Review
  4. Relationship between heart rate response and cardiac innervation in patients with suspected or known coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  5. α-Synuclein Deposition in Sympathetic Nerve Fibers in Genetic Forms of Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2021
    Observational
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Anna De RosaDepartment of Neurosciences and Reproductive and Odontostomatological Sciences, Federico II University, Via Pansini 5, 80131, Naples, Italy. anna_derosa@libero.it.
Teresa PellegrinoInstitute of Biostructure and Bioimaging, National Council of Research, Naples, Italy.
Sabina PappatàInstitute of Biostructure and Bioimaging, National Council of Research, Naples, Italy.
Maria Teresa PellecchiaCenter for Neurodegenerative Disease, University of Salerno-CEMAND, Salerno, Italy.
Silvio PelusoDepartment of Neurosciences and Reproductive and Odontostomatological Sciences, Federico II University, Via Pansini 5, 80131, Naples, Italy.
Francesco SaccàDepartment of Neurosciences and Reproductive and Odontostomatological Sciences, Federico II University, Via Pansini 5, 80131, Naples, Italy.
Paolo BaroneCenter for Neurodegenerative Disease, University of Salerno-CEMAND, Salerno, Italy.
Alberto CuocoloDepartment of Advanced Biomedical Sciences, Federico II University, Naples, Italy.
Giuseppe De MicheleDepartment of Neurosciences and Reproductive and Odontostomatological Sciences, Federico II University, Via Pansini 5, 80131, Naples, Italy.
Federico II University Hospital · ITInstitute of Biostructure and Bioimaging · ITUniversity of Salerno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPARK2 is an autosomal recessive parkinsonism caused by parkin gene mutations. Several Parkinson's Disease (PD) cases harbor single parkin mutations, raising a debate about the pathogenic meaning of heterozygous mutations. Here, we evaluate cardiac autonomic innervation in patients with either two or one parkin mutations compared to patients with idiopathic PD (IPD). PATIENTS AND

methodsMyocardial

resultsIn comparison to control group, IPD patients showed lower early and late heart-to-mediastinum (H/M) ratios and higher washout rates, whereas HET patients had only lower early H/M ratio, and PARK2 patients were not different for any parameter. At individual level, MIBG findings were abnormal in 7/8 IPD, in 4/6 HET and in 1/4 PARK2 patients.

conclusionsPreserved cardiac

Indexed as

3-IodobenzylguanidineAdultAgedAutonomic Nervous System DiseasesFemaleGenetic Predisposition to DiseaseHeartHumansMaleMiddle AgedMutationParkinson DiseasePolymorphism, Single NucleotideRadionuclide ImagingRadiopharmaceuticalsUbiquitin-Protein Ligases3-Iodobenzylguanidineparkin proteinRadiopharmaceuticalsUbiquitin-Protein Ligases123I-metaiodobenzylguanidine myocardial scintigraphyparkin geneParkinson’s Disease

Identifiers

PMID26626785
OpenAlexW2184228925

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.