Evidence map›Paper›PMID 26626770›Full record

ReviewCurrent hematologic malignancy reports2015

Cutaneous T cell Lymphoma: an Update on Pathogenesis and Systemic Therapy.

Catherine G Chung, Brian Poligone

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current hematologic malignancy reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Multidisciplinary Management of Mycosis Fungoides/Sézary Syndrome.Current hematologic malignancy reports · 2017
    Review
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Catherine G ChungDepartments of Dermatology and Pathology, Penn State Hershey Medical Center, 500 University Drive, Hershey, PA, 17033, USA. cchung1@hmc.psu.edu.
Brian PoligoneRochester Skin Lymphoma Medical Group, 6800 Pittsford Palmyra Road, Fairport, NY, 14450, USA. bpoligone@gmail.com.
Penn State Milton S. Hershey Medical Center · US

Funding

NF kappa B Activity in Skin Inflammation and CarcinogenesisK08AR055986 · NIAMS · UNIVERSITY OF ROCHESTER · PI POLIGONE, BRIAN · 2009 to 2013
$605k
NIAMS NIH HHS K08 AR055986
6 · The paper itself

Abstract

Mycosis fungoides (MF) and its leukemic variant, Sézary syndrome (SS), are malignancies of skin-homing T cells that comprise the majority of cutaneous T cell lymphomas (CTCL). Treatment of CTCL is limited and can be approached by skin-directed therapy or systemic therapy. Recent investigations into the pathogenesis of MF and SS have broadened the therapeutic targets; here, we review emerging concepts in the pathogenesis of MF and SS as well as novel and traditional systemic therapies for MF and SS. These include histone deacetylase inhibitors (vorinostat, romidepsin, panobinostat, and belinostat), monoclonal antibodies (alemtuzumab, brentuximab vedotin, and mogamulizumab) and single-agent cytotoxic chemotherapeutic agents (e.g., pralatrexate, doxorubicin, bendamustine, and forodesine), as well as multi-agent chemotherapy regimens.

Indexed as

Antibodies, MonoclonalAntineoplastic Combined Chemotherapy ProtocolsHumansLymphoma, T-Cell, CutaneousMycosis FungoidesAntibodies, MonoclonalChemotherapyCutaneous T cell lymphomaMonoclonal antibodiesPathogenesis

Identifiers

PMID26626770
OpenAlexW2281413742

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.