ArticleBMC health services research2015
Excess length of stay and economic consequences of adverse events in Dutch hospital patients.
Article in BMC health services research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04816968 (TAID Study - A Prospective Interventional Trial on Antibiotics Continuous Infusion at Home), which is not on this map. Cited by 37 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
TAID Study - A Prospective Interventional Trial on Antibiotics Continuous Infusion at Home
Who cites it
37 citing papers in PubMed, 4 syntheses or guidelines pooled it.
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- Prediction models for the prediction of unplanned hospital admissions in community-dwelling older adults: A systematic review.PloS one · 2022Pooled it
- Economic Burden of Stroke Disease: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Prevalence, severity, and nature of preventable patient harm across medical care settings: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2019Pooled it
- The Association Between Hospital Harms and 1-Year Mortality Following a Hip Fracture in Ontario, Canada: A Cohort Study.Journal of the American Geriatrics Society · 2026Article
- Risk factors associated with nursing-sensitive adverse events in older hospitalised patients: A retrospective chart review.International journal of nursing studies advances · 2026Article
- Length of hospital stay after uncomplicated gastrectomy in the Netherlands: a nationwide cohort study.Surgical endoscopy · 2026Article
- Impact of patient safety on hospital prognosis: Association between adverse events and in-hospital mortalit.Clinical medicine (London, England) · 2026Observational
- Key indicators contributing to prolonged emergency department stays in Saudi Arabia: a modified Delphi study.BMC emergency medicine · 2025Article
- Prevalence, Outcomes and Healthcare Costs of Postoperative ARDS Compared with Medical ARDS.Journal of clinical medicine · 2025Article
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- Determinant factors of prolonged hospitalization in acute heart failure patients at Jimma Medical Center, Southwest Ethiopia.Scientific reports · 2025Observational
- Novel Robotic Balloon-Based Device for Wrist-Extension Therapy of Hemiparesis Stroke Patients.Sensors (Basel, Switzerland) · 2025Article
- Broadening the definition of patient-safety events: lessons from a multicentre learning health system collaborative.BMJ open quality · 2025Article
- Epidemiological trends of mechanically ventilated acute respiratory distress syndrome in the twenty-first century: a nationwide, population-based retrospective study.Journal of intensive care · 2025Article
- Observational
- Anxiety and depression prior to total knee arthroplasty are associated with worse pain and subjective function: A prospective comparative study.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Article
- Streamlining patient flow and enhancing operational efficiency through case management implementation.BMJ open quality · 2024Article
- Assessing the excess costs of the in-hospital adverse events covered by the AHRQ's Patient Safety Indicators in Switzerland.PloS one · 2024Article
- Adverse Drug Reactions Related with Antibiotic Medicines in Malawi: A Retrospective Analysis of Prevalence and Associated Factors.Drug, healthcare and patient safety · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo investigate the average and extrapolated excess length of stay and direct costs of adverse events (AEs) and preventable AEs in Dutch hospitals, and to evaluate patient characteristics associated with excess length of stay and costs.
methodsData of a large retrospective patient record review study on AEs was used. A stratified sample of 20 Dutch hospitals was included. Excess length of stay and costs attributable to AEs and preventable AEs were calculated and extrapolated to a national estimate. The association between patient characteristics and excess length of stay (and costs thereof) attributable to AEs and preventable AEs was investigated through multilevel linear regression analyses.
resultsA total of 2975 patient records were included in the analysis, of which 325 experienced one or more AEs. Hospital patients experiencing an AE stayed 5.11 (95% CI 3.91-6.30) more days in hospital and cost €2600 (95% CI €1968-€3232) more compared to those without an AE. There was no significant difference in days and costs between preventable and non-preventable AEs. Extrapolated to a national level, AEs cost more than €300 million, which was 1.3% of the national hospital care budget. Patients with hospital-acquired infections had a statistically significant longer length of stay compared to the reference group (patients with AEs on the cardiovascular system).
conclusionsThis study showed that AEs lead to substantial excess length of stay and increased costs. Special attention should be paid to patients with AEs due to an hospital-acquired infection.
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