Evidence map›Paper›PMID 26626728›Full record

ArticleBMC palliative care2015

The relationship between pain management and psychospiritual distress in patients with advanced cancer following admission to a palliative care unit.

Ya-Ping Lee, Chih-Hsun Wu, Tai-Yuan Chiu, Ching-Yu Chen, Tatsuya Morita, Shou-Hung Hung, Sin-Bao Huang, Chia-Sheng Kuo, Jaw-Shiun Tsai

Abstract read
In one paragraph

Article in BMC palliative care, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Early analgesic response to interventional pain procedures in hospitalized patients with cancer-related pain: clinical predictors and exploratory survival analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  11. Pain and quality of life in breast cancer patients.Clinics (Sao Paulo, Brazil) · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ya-Ping LeeDivision of Family Medicine, Taipei Hospital, Ministry of Health and Welfare, New Taipei City, Taiwan. b91401032@ntu.edu.tw.
Chih-Hsun WuDepartment of Family Medicine, Hospice and Palliative Care Unit, College of Medicine and Hospital, National Taiwan University, 7 Chung-Shan South Road, Taipei, Taiwan. wuyehsun@gmail.com.
Tai-Yuan ChiuDepartment of Family Medicine, Hospice and Palliative Care Unit, College of Medicine and Hospital, National Taiwan University, 7 Chung-Shan South Road, Taipei, Taiwan. tychiu@ntuh.gov.tw.
Ching-Yu ChenDepartment of Family Medicine, Hospice and Palliative Care Unit, College of Medicine and Hospital, National Taiwan University, 7 Chung-Shan South Road, Taipei, Taiwan. chency@nhri.org.tw.
Tatsuya MoritaPalliative and Supportive Care Division, Seirei Mikatahara Hospital, Mikatahara, Kita, Hamamatsu, Japan. tmorita@sis.seirei.or.jp.
Shou-Hung HungDepartment of Community and Family Medicine, National Taiwan University Hospital Yun-Lin Branch, Yun-Lin, Taiwan. chaomei@ms14.hinet.net.
Sin-Bao HuangDepartment of Palliative Care, Changhua Christian Hospital, Changhua, Taiwan. heartbao@gmail.com.
Chia-Sheng KuoDepartment of Community and Family Medicine, National Taiwan University Hospital Yun-Lin Branch, Yun-Lin, Taiwan. omigodokuo@gmail.com.
Jaw-Shiun TsaiDepartment of Family Medicine, Hospice and Palliative Care Unit, College of Medicine and Hospital, National Taiwan University, 7 Chung-Shan South Road, Taipei, Taiwan. jawshiun@ntu.edu.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough many cross-sectional studies have demonstrated the association between cancer pain and psychospiritual distress, the time-dependent relationship has not been fully explored. For that reason, this study aims to investigate the time-dependent relationship between psychospiritual distress and cancer pain management in advanced cancer patients.

methodsThis is a prospective observational study. Two hundred thirty-seven advanced cancer patients were recruited from a palliative care unit in Taiwan. Demographic and clinical data were retrieved at admission. Pain and psychospiritual distress (i.e.: anxiety, depression, anger, level of family and social support, fear of death) were assessed upon admission and one week later, by using a "Symptom Reporting Form". Patients were divided into two groups according to the pain status one week post-admission (improved versus not improved groups).

resultsOne hundred sixty-three (68.8 %) patients were assigned to the improved group, and 74 (31.2 %) patients were assigned to the not improved group. There were no differences in the psychospiritual variables between groups upon admission. In overall patients, all psychospiritual variables improved one week post-admission, but the improvement of depression and family/social support in the not improved group was not significant. Consistent with this, for depression scores, there was a statistically significant pain group x time interaction effect detected, meaning that the pain group effect on depression scores was dependent on time.

conclusionsWe demonstrated a time-dependent relationship between depression and pain management in advanced cancer patients. Our results suggest that poor pain management may be associated with intractable depression. The inclusion of interventions that effectively improve psychospiritual distress may contribute to pain management strategies for advanced cancer patients.

Indexed as

HospitalsSocial SupportCross-Sectional StudiesFemaleHumansMaleNeoplasmsPainPain ManagementPalliative CareProspective StudiesSpiritual TherapiesTaiwan

Identifiers

PMID26626728
PMCPMC4667533

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.