Evidence map›Paper›PMID 26626628›Full record

ReviewJournal of proteomics2016

Glycomics: revealing the dynamic ecology and evolution of sugar molecules.

Stevan A Springer, Pascal Gagneux

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of proteomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Serum N-Glycome Diversity in Teleost and Chondrostrean Fishes.Frontiers in molecular biosciences · 2021
    Article
  9. Global view of human protein glycosylation pathways and functions.Nature reviews. Molecular cell biology · 2020
    Review
  10. Article
  11. Review
  12. Article
  13. PeerJ · 2018
    Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Stevan A SpringerGlycobiology Research and Training Center, University of California San Diego, La Jolla, CA 92039, USA; Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92039, USA. Electronic address: stevan.springer@gmail.com.
Pascal GagneuxGlycobiology Research and Training Center, University of California San Diego, La Jolla, CA 92039, USA; Department of Pathology, University of California San Diego, La Jolla, CA 92039, USA. Electronic address: pgagneux@ucsd.edu.

Funding

Glycan Diversity and Anti-Glycan Antibodies as Barriers to Gene FlowR01GM095882 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GAGNEUX, PASCAL · 2011 to 2015
$1.4M
NIGMS NIH HHS R01 GM095882
6 · The paper itself

Abstract

Sugars are the most functionally and structurally diverse molecules in the biological world. Glycan structures range from tiny single monosaccharide units to giant chains thousands of units long. Some glycans are branched, their monosaccharides linked together in many different combinations and orientations. Some exist as solitary molecules; others are conjugated to proteins and lipids and alter their collective functional properties. In addition to structural and storage roles, glycan molecules participate in and actively regulate physiological and developmental processes. Glycans also mediate cellular interactions within and between individuals. Their roles in ecology and evolution are pivotal, but not well studied because glycan biochemistry requires different methods than standard molecular biology practice. The properties of glycans are in some ways convenient, and in others challenging. Glycans vary on organismal timescales, and in direct response to physiological and ecological conditions. Their mature structures are physical records of both genetic and environmental influences during maturation. We describe the scope of natural glycan variation and discuss how studying glycans will allow researchers to further integrate the fields of ecology and evolution.

Indexed as

EcologyEvolution, MolecularGlycomicsPolysaccharidesPolysaccharidesCellular ecologyGlycansGlycoconjugatesNatural variationPolymorphism

Identifiers

PMID26626628
PMCPMC4762723

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.