Evidence map›Paper›PMID 26626237›Full record

ArticleEpidemiology and infection2016

High burden of RSV hospitalization in very young children: a data linkage study.

N Homaira, J-L Oei, K-A Mallitt, M E Abdel-Latif, L Hilder, B Bajuk, K Lui, M Ferson, A Nurkic, G M Chambers and 3 more

Abstract read
In one paragraph

Article in Epidemiology and infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Maternal Influenza Vaccine Reduces the Risk of Respiratory Syncytial Virus and Related Respiratory Hospitalizations in Early Infancy: An Epidemiological Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

N HomairaDiscipline of Paediatrics,School of Women's and Children's Health,Faculty of Medicine,UNSWAustralia.
J-L OeiDiscipline of Paediatrics,School of Women's and Children's Health,Faculty of Medicine,UNSWAustralia.
K-A MallittDiscipline of Paediatrics,School of Women's and Children's Health,Faculty of Medicine,UNSWAustralia.
M E Abdel-LatifDepartment of Neonatology,Centenary Hospital,Australian National University.
L HilderNational Perinatal Epidemiology & Statistics Unit,Centre for Big Data Research in Health and School of Women's and Children's Health,UNSWAustralia.
B BajukNSW Pregnancy and Newborn Services Network,Sydney Children's Hospitals Network,Westmead,NSW,Australia.
K LuiDiscipline of Paediatrics,School of Women's and Children's Health,Faculty of Medicine,UNSWAustralia.
M FersonPublic Health Unit,South Eastern Sydney Local Health District,NSW,Australia.
A NurkicPublic Health Unit,South Eastern Sydney Local Health District,NSW,Australia.
G M ChambersNational Perinatal Epidemiology & Statistics Unit,Centre for Big Data Research in Health and School of Women's and Children's Health,UNSWAustralia.
W RawlinsonSerology and Virology Division,SEALS Microbiology,Prince of Wales Hospital,Randwick,NSW,Australia.
T SnellingPrincess Margaret Hospital,Perth,Western Australia.
A JaffeDiscipline of Paediatrics,School of Women's and Children's Health,Faculty of Medicine,UNSWAustralia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Linked administrative population data were used to estimate the burden of childhood respiratory syncytial virus (RSV) hospitalization in an Australian cohort aged <5 years. RSV-coded hospitalizations data were extracted for all children aged <5 years born in New South Wales (NSW), Australia between 2001 and 2010. Incidence was calculated as the total number of new episodes of RSV hospitalization divided by the child-years at risk. Mean cost per episode of RSV hospitalization was estimated using public hospital cost weights. The cohort comprised of 870 314 children. The population-based incidence/1000 child-years of RSV hospitalization for children aged <5 years was 4·9 with a rate of 25·6 in children aged <3 months. The incidence of RSV hospitalization (per 1000 child-years) was 11·0 for Indigenous children, 81·5 for children with bronchopulmonary dysplasia (BPD), 10·2 for preterm children with gestational age (GA) 32-36 weeks, 27·0 for children with GA 28-31 weeks, 39·0 for children with GA <28 weeks and 6·7 for term children with low birthweight. RSV hospitalization was associated with an average annual cost of more than AUD 9 million in NSW. RSV was associated with a substantial burden of childhood hospitalization specifically in children aged <3 months and in Indigenous children and children born preterm or with BPD.

Indexed as

Child, PreschoolFemaleHealth Care CostsHospitalizationHumansIncidenceInfantInfant, NewbornInformation Storage and RetrievalMaleNew South WalesRespiratory Syncytial VirusesRespiratory Syncytial Virus InfectionsRetrospective StudiesEpidemiologyestimating disease prevalenceglobal vaccine issuesinfectious disease epidemiologypaediatrics

Identifiers

PMID26626237
PMCPMC9150613

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.