Evidence map›Paper›PMID 26626049›Full record

ArticleEuropean journal of clinical nutrition2016

The prevalence of anemia and iron deficiency is more common in breastfed infants than their mothers in Bhaktapur, Nepal.

R K Chandyo, S Henjum, M Ulak, A L Thorne-Lyman, R J Ulvik, P S Shrestha, L Locks, W Fawzi, T A Strand

Abstract read
In one paragraph

Article in European journal of clinical nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

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  14. A Retrospective Case-Control Study of the Determinants of Iron Deficiency Anemia in Infants in an Urban Community in Shanghai, China Between 2010-2015.Medical science monitor : international medical journal of experimental and clinical research · 2020
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

R K ChandyoCentre for International Health, University of Bergen, Bergen, Norway.
S HenjumOslo and Akershus University College of Applied Science, Oslo, Norway.
M UlakDepartment of Child Health, Institute of Medicine, Kathmandu, Nepal.
A L Thorne-LymanWorldFish, Malaysia, Bayan Lepas, Malaysia.
R J UlvikDepartment of Clinical Science, University of Bergen, Bergen, Norway.
P S ShresthaDepartment of Child Health, Institute of Medicine, Kathmandu, Nepal.
L LocksDepartment of Nutrition, Harvard School of Public Health, Boston, MA, USA.
W FawziDepartment of Nutrition, Harvard School of Public Health, Boston, MA, USA.
T A StrandCentre for International Health, University of Bergen, Bergen, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesIron deficiency anemia is a widespread public health problem, particularly in low- and middle-income countries. Maternal iron status around and during pregnancy may influence infant iron status. We examined multiple biomarkers to determine the prevalence of iron deficiency and anemia among breastfed infants and explored its relationship with maternal and infant characteristics in Bhaktapur, Nepal. SUBJECTS/

methodsIn a cross-sectional survey, we randomly selected 500 mother-infant pairs from Bhaktapur municipality. Blood was analyzed for hemoglobin, ferritin, total iron-binding capacity, transferrin receptors and C-reactive protein.

resultsThe altitude-adjusted prevalence of anemia was 49% among infants 2-6-month-old (hemaglobin (Hb) <10.8 g/dl) and 72% among infants 7-12-month-old (Hb <11.3 g/dl). Iron deficiency anemia, defined as anemia and serum ferritin <20 or <12 μg/l, affected 9 and 26% of infants of these same age groups. Twenty percent of mothers had anemia (Hb <12.3 g/dl), but only one-fifth was explained by depletion of iron stores. Significant predictors of infant iron status and anemia were infant age, sex and duration of exclusive breastfeeding and maternal ferritin concentrations.

conclusionsOur findings suggest that iron supplementation in pregnancy is likely to have resulted in a low prevalence of postpartum anemia. The higher prevalence of anemia and iron deficiency among breastfed infants compared with their mothers suggests calls for intervention targeting newborns and infants.

Indexed as

Breast FeedingIron DeficienciesAdultAnemia, Iron-DeficiencyBiomarkersC-Reactive ProteinCross-Sectional StudiesDietary SupplementsFerritinsFollow-Up StudiesHemoglobinsHumansInfantIronIron, DietaryLinear ModelsBiomarkersC-Reactive ProteinFerritinsHemoglobinsIronIron, DietaryReceptors, Transferrin

Identifiers

PMID26626049
PMCPMC4827010

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.