ArticleBMC cancer2015
Difficulty of predicting the presence of lymph node metastases in patients with clinical early stage gastric cancer: a case control study.
Article in BMC cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Machine learning for lymph node metastasis prediction of in patients with gastric cancer: A systematic review and meta-analysis.Frontiers in oncology · 2022Pooled it
- Pooled it
- Genomic and evolutionary characteristics of metastatic gastric cancer by routes.British journal of cancer · 2023Article
- Risk of lymph node metastasis in early gastric cancer and indications for endoscopic resection: is it worth applying the east rules to the west?Surgical endoscopy · 2021Article
- Lymph Node Involvement in Advanced Gastric Cancer in the Era of Multimodal Treatment-Oncological and Surgical Perspective.Cancers · 2021Review
- Development and validation of a nomogram for preoperative prediction of lymph node metastasis in early gastric cancer.World journal of surgical oncology · 2020Article
- Establishment of Decision Rules and Risk Assessment Model for Preoperative Prediction of Lymph Node Metastasis in Gastric Cancer.Frontiers in oncology · 2020Article
- Clinical Implications of Microsatellite Instability in Early Gastric Cancer.Journal of gastric cancer · 2019Article
- Combined effect of volumetric breast density and body mass index on breast cancer risk.Breast cancer research and treatment · 2019Article
- Construction and external validation of a nomogram that predicts lymph node metastasis in early gastric cancer patients using preoperative parameters.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2018Article
- Risk factors for lymph node metastasis in early gastric cancer patients: Report from Eastern Europe country- Lithuania.BMC surgery · 2017Article
- The longest diameter of tumor as a parameter of endoscopic resection in early gastric cancer: In comparison with tumor area.PloS one · 2017Article
- Prediction of lymph node metastasis and sentinel node navigation surgery for patients with early-stage gastric cancer.World journal of gastroenterology · 2016Review
- A Lymph Node Staging System for Gastric Cancer: A Hybrid Type Based on Topographic and Numeric Systems.PloS one · 2016Article
- The era of laparoscopic surgery for gastric cancer: what is the present territory and what will be next?Translational gastroenterology and hepatology · 2016Article
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe relationship between pathological factors and lymph node metastasis of pathological stage early gastric cancer has been extensively investigated. By contrast, the relationship between preoperative factors and lymph node metastasis of clinical stage early gastric cancer has not been investigated. The present study was to investigate discrepancies between preoperative and postoperative values.
methodsFrom January 2011 to December 2013, 1042 patients with clinical stage early gastric cancer who underwent gastrectomy with lymphadenectomy were enrolled. Preoperative and postoperative values were collected for subsequent analysis. Receiver operating characteristics curves were computed using independent predictive factors.
resultsSeveral discrepancies were observed between preoperative and postoperative values, including existence of ulcer, gross type, and histology (all McNemar p-values were <0.001). Multivariate analyses identified the following independent predictive factors for lymph node metastasis: postoperative values including age (p = 0.002), tumor size (p < 0.001), and tumor depth (p < 0.001); preoperative values including age (p = 0.017), existence of ulcer (p = 0.037), tumor size (p = 0.009), and prediction of the presence of lymph node metastasis in computed tomography scans (p = 0.002). These postoperative and preoperative independent predictive factors produced areas under the receiver operating characteristics curves of 0.824 and 0.660, respectively.
conclusionsSurgeons need to be aware of limitations in preoperative predictions of the presence of lymph node metastasis for clinical stage early gastric cancer.
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